Older adults Dotaz Zobrazit nápovědu
The frailty syndrome is a common clinical marker of vulnerability in older adults conducive to an overall decline in inflammatory stress responsiveness; yet little is known about the genetic risk factors for frailty in elderly. Our aim was to investigate the association between the rs2476601 polymorphism in PTPN22 gene and susceptibility to frailty in Mexican older adults. Data included 630 subjects 70 and older from The Coyoacán cohort, classified as frail, pre-frail, and non-frail following Fried's criteria. Sociodemographic and clinical characteristics were compared between groups at baseline and after a multivariate analysis. The rs2476601 polymorphism was genotyped by TaqMan genotyping assay using real-time PCR and genotype frequencies were determined for each frailty phenotype in all participants and subsets by age range. Genetic association was examined using stratified and interaction analyses adjusting for age, sex and variables selected in the multivariate analysis. Disability for day-life activities, depression and cognitive impairment were associated with the risk of pre-frailty and frailty at baseline and after adjustment. Carrying the T allele increased significantly the risk of frailty in patients 76 and older (OR 5.64, 95% CI 4.112-7.165) and decreased the risk of pre-frailty under no clinical signs of depression (OR 0.53; 95% CI 0.17-1.71). The PTPN22 polymorphism, rs2476601, could be a genetic risk factor for frailty as subject to quality of life. This is the first study analyzing such relationship in Mexican older adults. Confirming these findings requires additional association studies on wider age ranges in populations of older adults with frailty syndrome.
- Klíčová slova
- Frailty syndrome, Lymphoid tyrosine phosphatase locus (LYP/PTPN22), Multivariate analysis, Older adults, PTPN22 gene polymorphism, SNP rs2476601,
- MeSH
- alely MeSH
- fenotyp MeSH
- genetická predispozice k nemoci * MeSH
- genetické asociační studie * MeSH
- genotyp MeSH
- jednonukleotidový polymorfismus genetika MeSH
- kohortové studie MeSH
- křehkost genetika patofyziologie MeSH
- křehký senior MeSH
- kvalita života MeSH
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- tyrosinfosfatasa nereceptorového typu 22 genetika MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Mexiko epidemiologie MeSH
- Názvy látek
- PTPN22 protein, human MeSH Prohlížeč
- tyrosinfosfatasa nereceptorového typu 22 MeSH
Despite efforts to expand global physical activity (PA) surveillance data to include both low- and high-income countries worldwide, our understanding of the relationship between PA and quality of life (QOL) in older adults from culturally diverse backgrounds is limited. We tested McAuley's social-cognitive model of the PA-QOL relationship in the cultural context of the Czech Republic, a post-communist central European country. A total of 546 older Czech adults (mean age 68 years) completed a battery of questionnaires assessing indicators of PA, self-efficacy, health status, and global QOL. A structural equation model was used to test the relationship between PA and QOL. The model hypothesized an indirect relationship between PA and QOL: PA predicted self-efficacy, which in turn predicted global QOL through mental and physical health status. The analyses indicated an acceptable fit of the proposed model, albeit with different emphases than those of studies from Western countries. Above all, we observed a stronger effect of PA on self-efficacy and a weaker mediating effect of health status on the PA-QOL relationship. Our findings supported the validity of McAuley's PA-QOL social-cognitive model for a non-Western cultural context. However, it seems that self-efficacy and health status may influence the PA-QOL relationship in this population in a manner different from that proposed in McAuley's model.
- Klíčová slova
- Health status, Older adults, Physical activity, Quality of life, Self-efficacy, Social cognitive, Structural equation modeling,
- Publikační typ
- časopisecké články MeSH
We tested a social cognitive model of physical activity (PA) in the cultural context of the Czech Republic, a postcommunist central European country. In total, 546 older Czech adults (mean age = 68 years, data collected in 2013) completed a battery of questionnaires assessing indicators of PA and related social cognitive constructs, including self-efficacy, social support, and self-regulation strategies. Subsequently, a structural equation model was used to test the relationship between the social cognitive constructs and PA. Our analyses indicated an acceptable fit of the proposed model (CFI = .911; SRMR = .046; RMSEA = .073). Self-regulation was predicted by self-efficacy (β = .67) and social support (β = .23), which predicted PA (β = .45). The model explained 60.4% of the variance in PA self-regulation and 20.5% of the variance in PA participation. The results provide further evidence for the role of self-efficacy and social support in enabling PA in older adults, and suggest that this relationship is partially mediated by self-regulation.
- Klíčová slova
- older adults, physical activity, self-efficacy, self-regulation, social cognitive, social support, structural equation modeling,
- MeSH
- cvičení psychologie MeSH
- geriatrické hodnocení MeSH
- kognice fyziologie MeSH
- lidé MeSH
- sebeuplatnění MeSH
- senioři MeSH
- sociální determinanty zdraví * MeSH
- sociální opora MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
BACKGROUND: Attention is focused on the health and physical fitness of older adults due to their increasing age. Maintaining physical abilities, including safe walking and movement, significantly contributes to the perception of health in old age. One of the early signs of declining fitness in older adults is limited mobility. Approximately one third of 70-year-olds and most 80-year-olds report restrictions on mobility in their apartments and immediate surroundings. Restriction or loss of mobility is a complex multifactorial process, which makes older adults prone to falls, injuries, and hospitalizations and worsens their quality of life while increasing overall mortality. OBJECTIVE: The objective of the study is to identify the factors that have had a significant impact on mobility in recent years and currently, and to identify gaps in our understanding of these factors. The study aims to highlight areas where further research is needed and where new and effective solutions are required. METHODS: The PRISMA methodology was used to conduct a scoping review in the Scopus and Web of Science databases. Papers published from 2007 to 2021 were searched in November 2021. Of these, 52 papers were selected from the initial 788 outputs for the final analysis. RESULTS: The final selected papers were analyzed, and the key determinants were found to be environmental, physical, cognitive, and psychosocial, which confirms the findings of previous studies. One new determinant is technological. New and effective solutions lie in understanding the interactions between different determinants of mobility, addressing environmental factors, and exploring opportunities in the context of emerging technologies, such as the integration of smart home technologies, design of accessible and age-friendly public spaces, development of policies and regulations, and exploration of innovative financing models to support the integration of assistive technologies into the lives of seniors. CONCLUSION: For an effective and comprehensive solution to support senior mobility, the determinants cannot be solved separately. Physical, cognitive, psychosocial, and technological determinants can often be perceived as the cause/motivation for mobility. Further research on these determinants can help to arrive at solutions for environmental determinants, which, in turn, will help improve mobility. Future studies should investigate financial aspects, especially since many technological solutions are expensive and not commonly available, which limits their use.
- Klíčová slova
- Determinants, Financial aspects, Mobility, Older adults, Technological solutions,
- MeSH
- chůze * MeSH
- cvičení MeSH
- databáze faktografické MeSH
- kvalita života * MeSH
- lidé MeSH
- senioři MeSH
- tělesná výkonnost MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
OBJECTIVES: This study examined the association between childhood adversity and late-life cognitive outcomes among older Puerto Rican adults. METHODS: Data were from the PREHCO study, a population-based cohort of 3,713 older Puerto Rican adults (mean age 72.5 years; 60% female). Adverse childhood experiences (ACEs) were categorised into four factors: economic hardship, parental illiteracy, childhood illness, and neighbourhood disadvantage. Cognition was assessed with the Mini-Mental Cabán (MMC). For our analyses, cognitive impairment was defined as scoring 1.5 SD below expected score, adjusted for age, sex, education, and reading ability. Ordinal logistic regression (baseline) and generalised linear mixed models (all three waves) analysed MMC scores; generalised estimating equations assessed incident cognitive impairment (waves 2 and 3). RESULTS: All four adversity factors were associated with poorer MMC scores at baseline. Parental illiteracy (β=-0.35, p<.001) and neighbourhood disadvantage (β=-0.27, p<.001) showed stronger associations than economic hardship (β=-0.10, p=.003) and childhood illness (β=-0.21, p<.001). No factors were significantly related to changes in cognitive scores over time. Depressive symptoms and self-rated health partially mediated cross-sectional relationships, with depressive symptoms showing a stronger effect. All adversity factors except economic hardship were linked to baseline cognitive impairment (OR=1.42 parent illiteracy, OR=1.24 childhood illness, OR=1.82 neighbourhood disadvantage, p<.05). Only neighbourhood disadvantage was associated with incident cognitive impairment (OR=1.19, p=.003). DISCUSSION: This study highlights the lasting impact of childhood adversity on late-life cognitive health among older Puerto Ricans, suggesting that addressing early adversity may promote cognitive health later in life.
- Klíčová slova
- Adverse childhood experiences (ACEs), cognitive decline, early adversity and aging, mental health in later life, older Hispanic adults,
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Patient safety strategies highlight patients' own active involvement in ensuring medication safety. A prerequisite for involving patients in their medication therapy is having tools that can assist them in ensuring safe medicine use. Older home-dwelling adults with multiple medications are at high risk for medication-related problems, yet only a few age-specific patient self-administered medication risk screening tools exist. This study aimed to develop, validate, and assess the feasibility of a self-administered medication risk checklist for home-dwelling older adults ≥65 years. MATERIALS AND METHODS: The draft checklist was formed based on a validated practical nurse-administered Drug Related Problem Risk Assessment Tool supplemented with findings from two systematic literature reviews. The content validity of the draft checklist was determined by a three-round Delphi survey with a panel of 19 experts in geriatric care and pharmacotherapy. An agreement of ≥80% was required. A feasibility assessment (i.e. understandability of the items, fill-out time of the checklist) of the content-validated checklist was conducted among older adults ≥65 years (n = 87) visiting community pharmacies (n = 4). Data were analysed using qualitative content analysis. RESULTS: The final validated and feasibility-tested Medication Risk Checklist (LOTTA) for home-dwelling older adults consists of eight items screening the highest priority systemic risks (three items), potentially drug-induced symptoms (one item), adherence, and self-management problems (four items). The checklist proved feasible for self-administration, the mean fill-out time being 6.1 min. CONCLUSIONS: A wide range of potential medication risks related to the medication use process can be identified by patient self-assessment. Screening tools such as LOTTA can enhance early detection of potential medication risks and risk communication between older adults and their healthcare providers. A wider and more integrated use of the checklist could be facilitated by making it electronically available as part of the patient information systems.
Patient safety strategies highlight patients’ own active involvement in ensuring medication safety, which in turn, requires easy-to-use tools to self-assess potential medication risks and communicate them with healthcare providers.This study produced a short, age-specific eight item Medication Risk Checklist (LOTTA) to be self-administered by home-dwelling older adults to identify major systemic risks, potential drug-induced symptoms, adherence, and self-management problems related to medication taking.To facilitate the use of the checklist in early detection of potential medication risks, future studies should focus on converting the LOTTA list into electronic form and pilot its use as an integrated part of the electronic patient information system.
- Klíčová slova
- Medication therapy, older adults, patient safety, primary care, risk screening, self-management,
- MeSH
- bezpečnost pacientů MeSH
- kontrolní seznam * MeSH
- lidé MeSH
- sebezhodnocení (psychologie) * MeSH
- senioři MeSH
- zdravotnický personál MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: Dignity is a multidimensional construct that includes perception, knowledge, and emotions related to competence or respect. Attitudes to aging are a comprehensive personal view of the experience of aging over the course of life, which can be influenced by various factors, such as the levels of health and self-sufficiency and social, psychological, or demographic factors. AIM: The purpose of this study was to explore the attitudes to aging of home-dwelling and inpatient older adults, and whether dignity and other selected factors belong among the predictors influencing attitudes to aging in these two different groups of older adults. RESEARCH DESIGN: Cross-sectional study using a set of questionnaires: Patient Dignity Inventory, Attitudes to Aging Questionnaire, and Barthel Index. Pearson and Spearman correlation analyses and multivariable linear regression were used for statistical processing. PARTICIPANTS AND RESEARCH CONTEXT: 233 inpatients and 237 home-dwelling older adults participated in the research in two regions of the Czech Republic. ETHICAL CONSIDERATIONS: Institutional Review Board approval was received from the authors' university. FINDINGS: The inpatients had more negative attitudes to aging (M = 74.9±10.9; P <0.0001). The predictors of their attitudes to aging were gender and dignity. Women (β = -2.969, P = 0.045) and inpatients with poor dignity ratings (β = -0.332, P <0.0001) had more negative attitudes to aging. The predictors for home-dwelling older adults were education, living arrangement, and dignity. More negative attitudes to aging were found in older adults with lower levels of education (β = 2.716, P = 0.007) who lived alone (β = 2.163, P = 0.046) and rated their dignity as low (β = -0.325, P <0.0001). DISCUSSION AND CONCLUSIONS: The results of this study add to the understanding that a sense of dignity is an important predictor of attitudes to aging for both home-dwelling older adults and inpatients.
- Klíčová slova
- areas of practice, attitude to aging, care of the older person, dignity in care, home-dwelling older adult, inpatient, topic areas,
- MeSH
- lidé MeSH
- postoj MeSH
- průřezové studie MeSH
- průzkumy a dotazníky MeSH
- senioři MeSH
- stárnutí * psychologie MeSH
- uznání * MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Cardiac rehabilitation is a beneficial multidisciplinary treatment of exercise promotion, patient education, risk factor management, and psychosocial counseling for people with coronary heart disease (CHD) that is underutilized due to substantial disparities in access, referral, and participation. Empirical studies suggest that cardiac telerehabilitation (CTR) have safety and efficacy comparable to traditional in-person cardiac rehabilitation, however, older adults are under-reported with effectiveness, feasibility, and usability remains unclear. METHODS: The study randomized 43 older adults (84 % males) to the 12-week CTR intervention or standard of care. Guided by Social Cognitive Theory, participants received individualized in-person assessment and e-coaching sessions, followed by CTR usage at home. Data were collected at baseline (T0), six-week (T1), and 12-week (T2). RESULTS: Participants in the CTR intervention group showed significant improvement in daily steps (T1: β = 4126.58, p = 0.001; T2: β = 5285, p = 0.01) and health-promoting lifestyle profile (T1: β = 23.26, p < 0.001; T2: β = 12.18, p = 0.008) across study endpoints. Twenty participants completed the intervention, with 40 % used the website for data-uploading or experiential learning, 90 % used the pedometer for tele-monitoring. Improving awareness of rehabilitation and an action focus were considered key facilitators while physical discomforts and difficulties in using the technology were described as the main barriers. CONCLUSIONS: The CTR is feasible, safe and effective in improving physical activity and healthy behaviors in older adults with CHD. Considering the variation in individual cardiovascular risk factors, full-scale RCT with a larger sample is needed to determine the effect of CTR on psychological symptoms, body weight and blood pressure, and quality of life.
- Klíčová slova
- Cardiac telerehabilitation, Coronary heart disease, Older adults, Pilot, Randomized controlled trial,
- Publikační typ
- časopisecké články MeSH
Physical activity (PA) is crucial for maintaining good health of older adults and owning a dog and walking it can enforce it. The purpose of this study was to evaluate the effect of dog ownership on PA in older adults as well as its positive impact on perceived degree of health, and sleep. There were 44 participants of mean age 68 ± 5.4 years (18 males, 26 females) enrolled in this study (dog owners-DO, n = 26; non-dog owners-NDO, n = 18). Xiaomi Mi Band 2 accelerometer, International Physical Activity Questionnaire- Short form (IPAQ-Short Form) and SF-36 questionnaires were used to measure the level of PA, sleep, and subjective health. A statistically significant difference was observed in favor of dog owners in most of the monitored parameters. All accelerometer PA parameters (step count, activity time, distance, calories) showed a significant difference at a p < 0.01. Sleep parameters were significant in total sleep length (p = 0.05) and light sleep length (p < 0.05). DO reported higher total PA time (min/week), MET/min/week spent in walking, and spent calories/week (p < 0.05). In SF-36 they reported higher score (p < 0.05) in general health, physical functioning, social functioning, pain, vitality, and emotional well-being. Body mass index (BMI) was significantly lower in the DO group (p < 0.01). The results suggest that dog ownership may affect the overall PA and health of older adults.
- Klíčová slova
- dog ownership, health, older adults, physical activity,
- MeSH
- akcelerometrie MeSH
- chůze statistika a číselné údaje MeSH
- cvičení * MeSH
- diagnostické sebehodnocení * MeSH
- domácí zvířata * MeSH
- duševní zdraví MeSH
- energetický příjem MeSH
- index tělesné hmotnosti MeSH
- lidé středního věku MeSH
- lidé MeSH
- prospektivní studie MeSH
- průzkumy a dotazníky MeSH
- psi * MeSH
- senioři MeSH
- spánek * MeSH
- vlastnictví MeSH
- zpráva o sobě MeSH
- zvířata MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- psi * MeSH
- senioři MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
The current study examined how neighborhood environments are related to older adults' perceived control over time. A longitudinal study design was employed using data sampled from the Health and Retirement Study (HRS) 2014 and 2018. In total, 3170 older adults, whose age ranged between 60 and 99 years at the baseline, were followed up with a 4-year lag. Measures included two domains of neighborhood characteristics: social cohesion and physical disorder (at baseline and follow-up) and perceived control (at follow-up). Path coefficients between the latent factors were examined using structural equation modeling. Results showed that there was a significant cross-sectional and longitudinal association between neighborhood social cohesion and older adults' perceived control, while neighborhood physical disorder was cross-sectionally associated with perceived control. Study findings provide evidence for promoting social integration and social capital in their neighborhood that might contribute to older adults' perceived competence and beliefs in control.
