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Critical illness polyneuromyopathy - a well-known but still controversial entity
Bednařík J., Vondráček P.
Jazyk angličtina Země Česko
Typ dokumentu přehledy
NLK
Masaryk University Scholarly Journals
od 2000 do 2010
- MeSH
- biopsie metody využití MeSH
- diagnostické techniky neurologické využití MeSH
- diferenciální diagnóza MeSH
- elektrofyziologie metody MeSH
- elektronová mikroskopie metody využití MeSH
- Guillainův-Barrého syndrom diagnóza etiologie MeSH
- jednotky intenzivní péče využití MeSH
- kritický stav MeSH
- lidé MeSH
- myasthenia gravis diagnóza etiologie MeSH
- nemoci svalů diagnóza etiologie klasifikace MeSH
- neuromuskulární nemoci diagnóza etiologie klasifikace MeSH
- polyneuropatie diagnóza epidemiologie etiologie MeSH
- svalová slabost diagnóza etiologie patofyziologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
Two main clinical, pathological and electrophysiological types of acquired neuromuscular involvement in critically ill patients have been described in the past two decades: critical illness polyneuropathy and critical illness myopathy. However, there, still exist many controversies and unresolved questions regarding definition, terminology, diagnosis, and differentiation of what appears to be a spectrum of more or less overlapping neuromuscular disorders rather than distinct entities, and recently a new term – critical illness polyneuromyopathy (CIPM) has been coined. CIPM may present with muscle weakness and failure to wean from mechanical ventilation, but is discovered more often and earlier by electrophysiological examination. In this review, the incidence, clinical, electrophysiological and histopathological features, and risk factors of CIPM will be described. Among the most important risk factors for CIPM are sepsis or systemic inflammatory response syndrome and the severity of multi-organ failure. Acquired neuromuscular weakness in critically ill patients should be regarded as a part rather than a complication of critical illness – dysfunction or failure of a further (neuromuscular) system.
Lit.: 63
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- $a Two main clinical, pathological and electrophysiological types of acquired neuromuscular involvement in critically ill patients have been described in the past two decades: critical illness polyneuropathy and critical illness myopathy. However, there, still exist many controversies and unresolved questions regarding definition, terminology, diagnosis, and differentiation of what appears to be a spectrum of more or less overlapping neuromuscular disorders rather than distinct entities, and recently a new term – critical illness polyneuromyopathy (CIPM) has been coined. CIPM may present with muscle weakness and failure to wean from mechanical ventilation, but is discovered more often and earlier by electrophysiological examination. In this review, the incidence, clinical, electrophysiological and histopathological features, and risk factors of CIPM will be described. Among the most important risk factors for CIPM are sepsis or systemic inflammatory response syndrome and the severity of multi-organ failure. Acquired neuromuscular weakness in critically ill patients should be regarded as a part rather than a complication of critical illness – dysfunction or failure of a further (neuromuscular) system.
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