Foraging rats learned to avoid footshock that was present in a part of a circular arena that was either stable or rotating slowly in a lighted room. The rotation dissociated spatial information in the separate reference frames of the room and arena. After learning to avoid the shocked region in either condition, in the absence of shock, memory for this place was expressed by simultaneous avoidance of an area defined in the reference frame of the room as well as of an area defined in the reference frame of the rotating arena. Spatial memories in these distinct reference frames were acquired, retrieved, and extinguished autonomously.

Institute of Physiology Academy of Sciences of the Czech Republic Videnska 1083 142 20 Prague 4 Czech Republic

See more in PubMed

Tolman E C. Psychol Rev. 1948;55:189–208. PubMed

O’Keefe J, Nadel L. The Hippocampus as a Cognitive Map. Oxford: Clarendon; 1978.

Bures J, Fenton A A, Kaminsky Yu, Rossier J, Sacchetti B, Zinyuk L. Philos Trans R Soc London B. 1997;352:1515–1524. PubMed PMC

Gallistel C R. The Organization of Learning. Cambridge, MA: MIT Press; 1990.

Mittelstaedt M-L, Glasauer S. Zool J Physiol. 1991;95:427–435.

Mittelstaedt M-L. In: Information Processing in the Visual Systems of Arthropods. Wehner R, editor. Berlin: Springer; 1972. pp. 275–279.

Mittelstaedt H, Mittelstaedt M-L. Fortschr Zool. 1973;21:46–58.

Sacchetti B, Wesierska M, Fenton A A, Bures J. Soc Neurosci Abstr. 1997;23:1592.

Bures J, Fenton A A, Kaminsky Yu, Wesierska M, Zahalka A. Neuropharmacology. 1998;37:689–699. PubMed

Bures J, Fenton A A, Kaminsky Yu, Zinyuk L. Proc Natl Acad Sci USA. 1997;94:243–250. PubMed PMC

Gothard K M, Skaggs W E, Moore K M, McNaughton B L. J Neurosci. 1996;16:823–835. PubMed PMC

McNaughton B L, Barnes C A, Gerrard J L, Gothard K M, Jung M W, Knierim J J, Kudrimoti H, Qin Y, Skaggs W E, Suster M, Weaver K L. J Exp Biol. 1996;199:173–185. PubMed

Whishaw I Q, McKenna J E, Maaswinkel H. Curr Opin Neurobiol. 1997;7:228–234. PubMed

Alyan S H, Paul B M, Ellsworth E, White R D, McNaughton B L. Soc Neurosci Abstr. 1997;23:504.

Wiener S I. J Neurosci. 1993;13:3802–3817. PubMed PMC

Chen L L, Lin L-H, Barnes C A, McNaughton B L. Exp Brain Res. 1994;101:24–34. PubMed

Leonhard C L, Stackman R W, Taube J S. Soc Neurosci Abstr. 1996;22:1873.

Knierim J J, Kudrimoti H S, McNaughton B L. J Neurosci. 1995;15:1648–1659. PubMed PMC

Stuchlik, A., Kaminsky, Yu, Zahalka, A. & Bures, J. (1998) Eur. J. Neurosci. 10, Suppl., 259 (abstr.).

Taube J S, Burton H L. J Neurophysiol. 1995;74:1953–1971. PubMed

Markus E J, Qin Y, Leonard B, Skaggs W E, McNaughton B L, Barnes C A. J Neurosci. 1995;15:7079–7094. PubMed PMC

Gothard K M, Skaggs W E, McNaughton B L. J Neurosci. 1996;16:8027–8040. PubMed PMC

Jeffery K J. Neuropharmacology. 1998;37:677–687. PubMed

Tanila H, Shapiro M L, Eichenbaum H. Hippocampus. 1997;7:613–623. PubMed

Shapiro M L, Tanila H, Eichenbaum H. Hippocampus. 1997;7:624–642. PubMed

Zinyuk, L. E., Kubik, S., Kaminsky, Yu. & Bures, J. (1998) Eur. J. Neurosci. 10 Suppl., 440 (abstr.).

Transient Inactivation of the Medial Prefrontal Cortex and Ventral Hippocampus Impairs Active Place Avoidance Retrieval on a Rotating Arena

Behavioral Alterations and Decreased Number of Parvalbumin-Positive Interneurons in Wistar Rats after Maternal Immune Activation by Lipopolysaccharide: Sex Matters

The McGill Transgenic Rat Model of Alzheimer's Disease Displays Cognitive and Motor Impairments, Changes in Anxiety and Social Behavior, and Altered Circadian Activity

Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits

Phencyclidine Discoordinates Hippocampal Network Activity But Not Place Fields

Drugs Interfering with Muscarinic Acetylcholine Receptors and Their Effects on Place Navigation

A Rat Model of Alzheimer's Disease Based on Abeta42 and Pro-oxidative Substances Exhibits Cognitive Deficit and Alterations in Glutamatergic and Cholinergic Neurotransmitter Systems

Temporal and spatial strategies in an active place avoidance task on Carousel: a study of effects of stability of arena rotation speed in rats

Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

The effect of psilocin on memory acquisition, retrieval, and consolidation in the rat

MK-801 Impairs Cognitive Coordination on a Rotating Arena (Carousel) and Contextual Specificity of Hippocampal Immediate-Early Gene Expression in a Rat Model of Psychosis

Cognitive disorganization in hippocampus: a physiological model of the disorganization in psychosis

Behavioral evidence that segregation and representation are dissociable hippocampal functions

Operant behavior can be triggered by the position of the rat relative to objects rotating on an inaccessible platform

Substratal idiothetic navigation of rats is impaired by removal or devaluation of extramaze and intramaze cues

Understanding hippocampal activity by using purposeful behavior: place navigation induces place cell discharge in both task-relevant and task-irrelevant spatial reference frames