Antibacterial C-geranylflavonoids from Paulownia tomentosa Fruits
Language English Country United States Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18293924
DOI
10.1021/np070446u
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents chemistry isolation & purification pharmacology MeSH
- Bacteria drug effects MeSH
- Candida albicans drug effects MeSH
- Circular Dichroism MeSH
- Flavonoids chemistry isolation & purification pharmacology MeSH
- Plants, Medicinal chemistry MeSH
- Microbial Sensitivity Tests * MeSH
- Molecular Structure MeSH
- Nuclear Magnetic Resonance, Biomolecular MeSH
- Fruit chemistry MeSH
- Scrophulariaceae chemistry MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Flavonoids MeSH
Eight C-6-geranylflavonoids ( 1- 8) were isolated from an ethanol extract of Paulownia tomentosa fruits. Tomentodiplacone ( 1), 3'- O-methyl-5'-hydroxydiplacone ( 2), 3'- O-methyl-5'- O-methyldiplacone ( 3), and tomentodiplacone B ( 4) were obtained as new compounds, and 3'- O-methyldiplacol ( 5) was isolated for the first time from a natural source. The structures of these new compounds were determined by using mass spectrometry (including HRMS) and 1D and 2D NMR spectroscopy, and the absolute configurations of the compounds were determined by circular dichroism. The antibacterial activities of 1- 8 against seven bacteria and yeast were evaluated.
References provided by Crossref.org
Prenylated Flavonoids in Topical Infections and Wound Healing
Phytochemical profile of Paulownia tomentosa (Thunb). Steud
