The protective potency of probiotic bacteria and their microbial products against enteric infections-review
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
- MeSH
- antibióza * MeSH
- Bacteria * růst a vývoj patogenita MeSH
- bakteriální infekce mikrobiologie prevence a kontrola MeSH
- Caco-2 buňky MeSH
- epitelové buňky imunologie metabolismus mikrobiologie MeSH
- gastrointestinální nemoci mikrobiologie prevence a kontrola MeSH
- lidé MeSH
- probiotika * MeSH
- proteiny tepelného šoku metabolismus MeSH
- střeva cytologie imunologie mikrobiologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- proteiny tepelného šoku MeSH
The intestinal environment accommodates a wide range of contents ranging from harmless beneficial dietary and microbial flora to harmful pathogenic bacteria. This has resulted in the development of highly adapted epithelial cells lining the intestine. This adaptation involves the potential of crypt cells to proliferate and to constantly replace villous cells that are lost due to maturity or death. As a result, the normal intestinal epithelial integrity and functions are maintained. This phenomenon is eminent in intestinal defense whereby the intestinal epithelial cells serve as a physical barrier against luminal agents. The protection against agents in the gut lumen can only be effective if the epithelium is intact. Restitution of the damaged epithelium is therefore crucial in this type of defense.
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