Targeting a global health problem: Vaccine design and challenges for the control of tick-borne diseases
Language English Country Netherlands Media print-electronic
Document type Journal Article, Review, Research Support, Non-U.S. Gov't
PubMed
28780117
DOI
10.1016/j.vaccine.2017.07.097
PII: S0264-410X(17)31023-X
Knihovny.cz E-resources
- Keywords
- Immunology, Omics, Risk, Tick, Tick-borne diseases, Vaccine,
- MeSH
- Global Health MeSH
- Ticks MeSH
- Humans MeSH
- Tick-Borne Diseases immunology prevention & control MeSH
- Vaccines immunology therapeutic use MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Vaccines MeSH
It has been over twenty years since the first vaccines for the control of tick infestations became commercially available. These vaccines proved their efficacy and the potential of this approach for the control of tick-borne diseases (TBDs), which represent a growing burden for human and animal health worldwide. In all these years, research in this area has produced new tick-derived and pathogen-derived candidate protective antigens. However, the potential of vaccines for the control of TBDs has been underestimated due to major challenges to reduce tick infestations, pathogen infection, multiplication and transmission, tick attachment and feeding time and/or host pathogen infection. Nevertheless, vaccines constitute the most safe and effective intervention for the control of TBDs in humans, domestic and wild animals.
Faculty of Veterinary Medicine University of Zaragoza Spain
SaBio Instituto de Investigación en Recursos Cinegéticos IREC 13005 Ciudad Real Spain
References provided by Crossref.org
Management Options for Ixodes ricinus-Associated Pathogens: A Review of Prevention Strategies
