Řada epidemiologických studií potvrdila souvislost mezi konzumací alkoholu a vznikem řady typů rakovin. Česká populace se řadí mezi populace s vyšší intenzitou úmrtnosti na rakovinu v Evropě a zároveň patří mezi populace s vysokou mírou konzumace alkoholu. Cílem příspěvku bylo odhadnout karcinogenní dopad konzumace alkoholu na zdraví české populace. Z celkového počtu 27 699 zemřelých na zhoubné novotvary v roce 2018 bylo 1 038 úmrtí přiřaditelných konzumaci alkoholu (774 u mužů a 264 u žen), což představovalo 3,7 % úmrtí na zhoubné novotvary v daném roce (5,1 % u mužů a 2,1 % u žen).
A causal relationship between alcohol consumption and several types of cancer has been shown by many studies. Large volumes of alcohol consumption and high cancer mortality among the Czech population has been observed, the main aim of this study was to estimate the share of cancer deaths attributable to alcohol consumption among the Czech population. In 2018, 3,7 % of total cancer deaths (27 699) were attributable to alcohol consumption (5,1 % in males and 2,1 % in females) which represented 1 038 deaths (774 in males and 264 in females).
This article investigates the health outcomes and determinants between two different European populations, Portuguese and Czech, on two hierarchical levels: country and metropolitan area. At first, the decomposition method of age and cause of death were compared on the country level, and then health was examined based on a factor analysis at the municipality level of Prague and Lisbon. The results clearly indicate problematic diabetes mortality among the Portuguese population, and especially in the Lisbon Metropolitan Area, and confirm the dominant role of circulatory mortality and cancer mortality among Czech, especially the Prague population. The social and economic deprivations were revealed as the major drivers for both metropolitan areas, although with differences between them, requiring interventions that go beyond the health sector.
- MeSH
- chudoba MeSH
- diabetes mellitus epidemiologie MeSH
- disparity zdravotního stavu * MeSH
- dítě MeSH
- dospělí MeSH
- kardiovaskulární nemoci epidemiologie MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- nádory epidemiologie MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- senioři MeSH
- socioekonomické faktory MeSH
- velkoměsta MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Česká republika MeSH
- Portugalsko MeSH
- velkoměsta MeSH
BACKGROUND: In the late 1980s, Czechia was among the countries which had the highest cardiovascular mortality in the world. In spite of enormous improvements since that time, there are still large opportunities in further improving cardiovascular health. METHODS: Based on the Czech Health, Alcohol and Psychosocial Factors in Eastern Europe sample (n=8449 at baseline, 12 years of follow-up, 494 cardiovascular disease (CVD) deaths up to 2015-events), the impact of selected covariates such as education, smoking habits, high blood pressure, blood cholesterol level, diabetes, obesity, physical activity and binge drinking and their multifactorial effects on cardiovascular mortality was evaluated by Cox regression. In addition, population attributable fractions (PAFs) were used to quantify the impact of these factors on CVD mortality in the population. RESULTS: Education was found as the strongest determinant of CVD mortality (primary vs university, HR 2.77, P<0.001; PAF=50.5%). CVD risk was two times higher for persons with diabetes compared with those without (HR 2.02, P<0.001, PAF=23.2%). Furthermore, significant factors found were smoking (smoker vs non-smoker, HR 1.91, P<0.001; PAF=26.5%), high blood pressure (HR 1.73, P<0.001; PAF=35.3%) and physical inactivity (none vs sufficient, HR 1.60, P<0.001; PAF=22.9%). Conversely, the effect of obesity was low (HR 1.29, P value =0.020), and binge drinking and high blood cholesterol level were not significant at all. CONCLUSIONS: Education had the largest impact on cardiovascular mortality among the Czech population. More than 50% of CVD death would be prevented if the whole population had the same risk values as the highest educated population. Reducing disparities in health related to education should benefit from attention to cardiovascular health literacy.
- MeSH
- cholesterol MeSH
- diabetes mellitus epidemiologie MeSH
- dospělí MeSH
- hypertenze epidemiologie MeSH
- kardiovaskulární nemoci epidemiologie mortalita MeSH
- komorbidita MeSH
- kouření MeSH
- lidé středního věku MeSH
- lidé MeSH
- nárazové pití alkoholu MeSH
- následné studie MeSH
- pití alkoholu epidemiologie MeSH
- senioři MeSH
- socioekonomické faktory MeSH
- stupeň vzdělání MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- MeSH
- chování mladistvých * MeSH
- kouření marihuany * epidemiologie MeSH
- kouření * epidemiologie MeSH
- lidé MeSH
- mladiství MeSH
- pití alkoholu * epidemiologie MeSH
- pití nezletilých MeSH
- průzkumy a dotazníky MeSH
- rizikové faktory MeSH
- výzkum MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- Geografické názvy
- Česká republika MeSH
- MeSH
- chování mladistvých * MeSH
- lidé MeSH
- mladiství MeSH
- rizikové faktory * MeSH
- školy MeSH
- sociální prostředí * MeSH
- výzkum MeSH
- životní prostředí * MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- Geografické názvy
- Česká republika MeSH
Determinants of cardiovascular diseases are well known; nowadays more than 300 of CVD risk factors are well-established. Important factors from population approach (public health approach) point of view are those which meet following criteria: high prevalence in population, are preventable and their control results in reducing of CVD risk. Survival analysis using the HAPIEE cohort data was applied to set down determinants of fatal cardiovascular events among Czech middle-aged population. High prevalence of several CVD risk factors was found. Favourable findings for all major risk factors, corresponding to low CVD risk, were uncovered just only in 0.5 % of population. The impact of education on CVD mortality was confirmed from socioeconomic determinants; from major risk factors the impact of smoking, high blood pressure and physical inactivity was establish. Conversely the influence of obesity, binge drinking habits and high total cholesterol was not significant. Joint influence of several risk factors increased the CVD risk and favourable findings for risk factors significantly decreased the CVD risk.
- MeSH
- dospělí MeSH
- kardiovaskulární nemoci * etiologie mortalita MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- rizikové faktory MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- statistika jako téma MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Česká republika MeSH
