OBJECTIVE: This study aims to evaluate the efficacy of the Uniform Data Set (UDS) 2 battery in distinguishing between individuals with mild cognitive impairment (MCI) attributable to Alzheimer's disease (MCI-AD) and those with MCI due to other causes (MCI-nonAD), based on contemporary AT(N) biomarker criteria. Despite the implementation of the novel UDS 3 battery, the UDS 2 battery is still used in several non-English-speaking countries. METHODS: We employed a cross-sectional design. A total of 113 Czech participants with MCI underwent a comprehensive diagnostic assessment, including cerebrospinal fluid biomarker evaluation, resulting in two groups: 45 individuals with prodromal AD (A+T+) and 68 participants with non-Alzheimer's pathological changes or normal AD biomarkers (A-). Multivariable logistic regression analyses were employed with neuropsychological test scores and demographic variables as predictors and AD status as an outcome. Model 1 included UDS 2 scores that differed between AD and non-AD groups (Logical Memory delayed recall), Model 2 employed also Letter Fluency and Rey's Auditory Verbal Learning Test (RAVLT). The two models were compared using area under the receiver operating characteristic curves. We also created separate logistic regression models for each of the UDS 2 scores. RESULTS: Worse performance in delayed recall of Logical Memory significantly predicted the presence of positive AD biomarkers. In addition, the inclusion of Letter Fluency RAVLT into the model significantly enhanced its discriminative capacity. CONCLUSION: Our findings demonstrate that using Letter Fluency and RAVLT alongside the UDS 2 battery can enhance its potential for differential diagnostics.
- MeSH
- Alzheimerova nemoc * diagnóza mozkomíšní mok MeSH
- amyloidní beta-protein mozkomíšní mok MeSH
- biologické markery * mozkomíšní mok MeSH
- diferenciální diagnóza MeSH
- kognitivní dysfunkce * diagnóza etiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- neuropsychologické testy * normy statistika a číselné údaje MeSH
- proteiny tau mozkomíšní mok MeSH
- průřezové studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: Although performance rating scales, spiral drawing, water pouring, and accelerometry are commonly used to assess tremor severity, the extent to which their results correlate with impairment in activities of daily living (ADL) remains unclear. OBJECTIVE: The aim was to identify the most effective predictors of ADL in essential tremor (ET). METHODS: Forty ET patients were examined using The Essential Tremor Rating Assessment Scale (TETRAS), spiral drawing, volume of water spilled, and accelerometric tremor power. Root-mean-square error, R2, and F-test were calculated for models predicting TETRAS ADL subscore. RESULTS: TETRAS Performance Subscale explained the variability in TETRAS ADL with an R2 value of 0.686. Models incorporating spiral rating and accelerometric tremor power (R2 = 0.731) and water spillage volume (R2 = 0.756) were not statistically superior. CONCLUSIONS: TETRAS performance subscore predicted nearly 70% ADL impairment in ET patients. Incorporating the spiral rating, accelerometric tremor power, and water pouring test did not enhance ADL estimation.
- MeSH
- akcelerometrie * metody MeSH
- činnosti denního života * MeSH
- esenciální tremor * patofyziologie diagnóza MeSH
- lidé středního věku MeSH
- lidé MeSH
- posuzování pracovní neschopnosti MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- stupeň závažnosti nemoci MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
Úvod: Tato studie hodnotí psychometrické vlastnosti české adaptace Škály suicidální ideace (Suicidal Ideation Attributes Scale, SIDAS) vyvinuté za účelem snadné online administrace a hodnotí její použití u LGBT+ osob. Metody: Pomocí konfirmační faktorové analýzy jsme zkoumali faktorovou strukturu a invarianci měření napříč jednotlivými LGBT+ skupinami ve výběrovém souboru 1 778 zúčastněných. Výsledky: Naše data podporují jednofaktorovou strukturu SIDAS a částečnou invarianci měření, což umožňuje porovnávání suicidální ideace mezi jednotlivými skupinami LGBT+ osob. SIDAS koreluje se škálami měřícími pocit osamělosti, dysregulaci emocí, vnímaný stres, ruminaci a životní spokojenost. Diskuse: SIDAS představuje cenný nástroj pro hodnocení sebevražedných myšlenek u LGBT+ osob, je vhodný pro online použití a má potenciál usnadňovat vývoj, plánování i vyhodnocování účinnosti cílených intervencí. Budoucí výzkum by měl prozkoumat stabilitu skóru v čase a vývoj dalších proměnných pro hodnocení závažnosti suicidality.
Introduction: This study assessed the psychometric properties of Czech adaptation of the Suicidal Ideation Assessment Scale (SIDAS) developed to enable online administration and evaluates its use among LGBT+ people. Methods: Using confirmatory factor analysis, we examined factor structure and measurement invariance across LGBT+ subgroups within a sample consisting of 1 778 participants. Results: We found a consistent one-factor structure and partial measurement invariance, enabling comparisons. SIDAS showed strong convergent validity with loneliness, emotion dysregulation, stress, rumination, and life satisfaction. Discussion: The adapted SIDAS proves valuable for assessing suicidal ideation within the LGBT+ community and is suitable for online administration; as such, it may help guide and assess the effects of targeted interventions. Future research should explore temporal dynamics and additional variables for severity assessment.
Objectives. The Lesbian, Gay, and Bisexual Identity Scale (LGBIS) is a well-known scale used to understand shared dimensions of sexual identity in otherwise diverse groups of non-heterosexuals. Yet only limited knowledge is available regarding the generalizability of the underlying psychological processes in regions such as Central and Eastern Europe. This study thus revisits the foundations of LGBIS and provides an in-depth examination of the psychometric properties of the new Czech adaptation. Method. The factor structure of LGBIS-CZ-6 was inspected via SEM. Convergent and content validity were examined via correlations with measures of related constructs (among others, psychological distress, suicidality, life satisfaction, social support, heterosexist harassment, rejection, and discrimination). Results. The results replicated the original structure of LGBIS on the Czech sample (N = 1 788) and proposed a better-fitting bifactor model. Generally, since LGBIS correlated with the majority of measures of related constructs in a predicted fashion, LGBIS-CZ-6 may be used as a well-functioning measure of the identity of non-heterosexuals. However, two subscales – internalized homonegativity and acceptance concerns showed problems with validity that might have arisen from Czech cultural specifics or by factors specific to broader post-socialist environments.
