The protective role of hyperimmune serum in the prevention of Haemophilus parasuis infections in post-weaned piglets was assessed by experimental challenge. The hyperimmune serum was obtained from a pig vaccinated with a commercial vaccine against Glässer's disease. Thirty-eight weaned piglets were divided into four groups: three groups were immunised intramuscularly with 10 ml of hyperimmune serum and one group consisted of unimmunised control animals. All piglets were subsequently infected intraperitoneally with H. parasuis serotype 5 at different times after immunisation. The use of hyperimmune serum provided the piglets with partial protection against experimental infection. The levels of protection indirectly depend on time between serum inoculation and challenge infection. The best protection of piglets against experimental infection was obtained in the group immunised 1 week before inoculation; the same group in which the highest levels of antibodies were detected at the time of challenge.
- MeSH
- ELISA veterinární MeSH
- Haemophilus parasuis imunologie izolace a purifikace MeSH
- hemofilové infekce imunologie prevence a kontrola veterinární MeSH
- hemofilové vakcíny imunologie MeSH
- lidé MeSH
- nemoci prasat imunologie prevence a kontrola MeSH
- odstavení MeSH
- pasivní imunizace metody MeSH
- polymerázová řetězová reakce veterinární MeSH
- prasata MeSH
- protilátky bakteriální krev MeSH
- Sus scrofa MeSH
- tkáňová distribuce MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- hodnotící studie MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- MeSH
- endometrium fyziologie MeSH
- ovarium fyziologie MeSH
- skot MeSH
- Check Tag
- skot MeSH
