Introduction: Obesity is increasingly reported to be a contributing factor to vascular diseases resulting in increased patient morbidity and mortality rates leading to increase healthcare expenses. More precisely, the lipid deposition in cardiac tissues is interesting, due to their direct contribution to the disease initiation, prognosis, and all subsequent patients' fate. We do focus on the determination of the link between changes in body mass index (BMI) and epicardial fat deposition concerning gastric operation.Objective: The objective of this work was to study the relationship between weight reduction and "epicardial thickness" after laparoscopic-sleeve gastrectomy.Methods: Critically-ill patients were recruited from private clinics and out-patients hospital clinics. Forty-two patients undergoing laparoscopic-sleeve gastrectomy due to morbid obesity were included in this research. Patients followed for four months after the operation.Results: The results of this work find there is significant weight reduction in these patients in parallel with a reduction of epicardial fat thickness.Conclusion: Patients who experience laparoscopic-sleeve gastrectomy showed a reduction in weight in a parallel reduction in epicardial fat thickness.

• MeSH
• bariatrická chirurgie metody   MeSH
• gastrektomie * metody   MeSH
• hmotnostní úbytek MeSH
• kardiovaskulární nemoci etiologie   MeSH
• laparoskopie metody   MeSH
• lidé MeSH
• morbidní obezita chirurgie   epidemiologie   komplikace   MeSH
• následné studie MeSH
• perikard * patologie   MeSH
• tuková tkáň * chirurgie   patologie   MeSH
• výsledek terapie MeSH
• Check Tag
• lidé MeSH

This article presents the author's technique and experience in the treatment of the flaccid "unhappy buttock" form with his surgical procedure of buttock lift by suture, without incision scars. The author first presented this new operation technique on a national level at the 2nd Annual Meeting of the National Bulgarian Society for Aesthetic Surgery and Aesthetic Medicine in Sofia on March 18, 1994 [1] and internationally at many scientific meetings over the world [2, 3, 4…]. The result is a visual change in the buttock position to a higher one, which elongates the lower limbs and changes the proportions between lower and upper half of the body. The aim of this study is to describe a miniinvasive procedure of beautification of the buttock form without scars by creating a lifting effect on the buttock's subcutaneous tissue, using a suture that takes the inferiorly positioned deep fibrose tissue and fixes it upwards to the sacrocutaneous fascia, discovered by the author. Aesthetic and technical considerations required properly sculpting the buttocks into a higher position, demonstrating nicely rounded form. Preoperative shape is discussed and patient evaluations, operative techniques, postoperative management and results after 4 years of experience are emphasized. 1032 female patients, and 26 male patients aged 1862 years, with ptosis and cellulite on the buttocks were treated since 1993 on an outpatient basis by the "Serdev suture technique without visible scars". Important instrumentarium is a long, curved, elastic needle and Polycon semielastic Bulgarian antimicrobial polycaproamide long term (in 2 years) absorbable surgical threads Polycon, produced in Bulgaria. This operation has been performed either alone or after ultrasonic assisted liposculpture (UAL) that reduces the amount of fat and heaviness. All patients reported a high degree of satisfaction. A stable improvement in the buttock position and form was observed for the period described. In the postoperative period the complication rate was minimal and resolved in the first 45 days post operative period. The skin puncture in the perianal zone makes antibiotic prophylaxis obligatory as well as a strict follow up for the first 7 days. Some pain in the sitting position was observed for at least 5 to 10 days, but all other social and professional duties and activities were possible. This outpatient procedure is effective in the correction of buttock laxity and ptosis and creates a new form, universally accepted as "happy buttocks".

• Klíčová slova
• technika Serdev,
• MeSH
• aplikace kožní MeSH
• hýždě * chirurgie   MeSH
• lidé MeSH
• lipektomie metody   MeSH
• miniinvazivní chirurgické výkony * metody   MeSH
• plastická chirurgie * MeSH
• postup MeSH
• představa o vlastním těle MeSH
• šicí techniky * MeSH
• sutura * využití   MeSH
• tuková tkáň chirurgie   MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH

Madelungova choroba (MCH) je vzácným onemocněním, které se v ORL oblasti projevuje symetrickou infiltrací povrchových i hlubokých krčních prostor lipomatózní tkání. Tuková tkáň svým postupným růstem nepůsobí obvykle obtíže, problémy dýchací a polykací se objevují až v případě, kdy utlačuje průdušnici, bronchy a horní jícen. Průběh onemocnění je benigního charakteru, případy maligní transformace u MCH jsou extrémně vzácné. Hlavním faktorem vzniku nemoci je defekt v adrenergní stimulaci lipolýzy. Jako kofaktor se uplatňuje dlouholetá nadměrná konzumace alkoholu. Základ léčby spočívá v exstirpaci tukové tkáně ze zevního přístupu, výběrově je možné užití liposukce.

Madelung's disease is a rare disorder, in otorhinolaryngology (ENT) it is manifested as a symmetrical infiltration of adipose tissue in superficial and deep cervical areas. Gradual growth of the adipose tissue usually does not cause problems; problems with breathing and swallowing come later, when it compresses trachea, bronchi and gullet. The course of the disease is usually benign, and cases of malignant transformation of MCH are extremely rare. The principal etiological factor is a defect of adrenergic stimulation of lipolysis. A long term excessive alcohol abuse is a cofactor. The treatment is based in extirpation of adipose tissue by the external approach, liposuction may be used selectively.

• MeSH
• beta-3-adrenergní receptory metabolismus   nedostatek   MeSH
• lidé středního věku MeSH
• lidé MeSH
• lipolýza fyziologie   MeSH
• mnohočetná symetrická lipomatóza diagnóza   komplikace   terapie   MeSH
• poruchy způsobené alkoholem MeSH
• tuková tkáň chirurgie   patologie   MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH

• MeSH
• lipektomie MeSH
• plastická chirurgie metody   MeSH
• tuková tkáň chirurgie   MeSH
• Publikační typ
• monografie MeSH

• Konspekt
• Patologie. Klinická medicína
• NLK Obory
• plastická chirurgie

Congenital abnormalities, various diseases and injuries may result in the degeneration of articular cartilage. Recently, stem cell therapy has offered new treatment possibilities for this condition. The aim of our study was to verify the chondrogenic differentiation potential of human bone marrow mesenchymal stem cells (BMSCs) and adipose tissue-derived mesenchymal stem cells (AMSCs) in vitro in the presence or absence of transforming growth factor beta (TGF-beta1). Human BMSCs and AMSCs from healthy donors were collected during orthopaedic surgeries and expanded in vitro to obtain a sufficient quantity of cells; their chondrogenic differentiation was studied in the pellet culture system. Spontaneous chondrogenesis occurred in both BMSC and AMSC pellet cultures and was similar in both TGF-beta1 treated and untreated pellet cultures. BMSC pellets contained more cells with a chondrogenic phenotype. The presence of TGF-beta1 led to a decrease in the levels of collagen type I mRNA and to increased levels of collagen type II mRNA only in the BMSC pellet culture. Our results demonstrate that although both mesenchymal cell types can be used in cartilage tissue engineering, the chondrogenic potential of human BMSCs is higher than that of AMSCs.

• MeSH
• finanční podpora výzkumu jako téma MeSH
• imunohistochemie metody   využití   MeSH
• kloubní chrupavka abnormality   patologie   růst a vývoj   MeSH
• kolagen typ II fyziologie   genetika   MeSH
• kostní dřeň fyziologie   chirurgie   MeSH
• kultivované buňky fyziologie   transplantace   MeSH
• lidé MeSH
• mezenchymální kmenové buňky fyziologie   MeSH
• polymerázová řetězová reakce s reverzní transkripcí metody   využití   MeSH
• transformující růstový faktor beta1 terapeutické užití   MeSH
• tuková tkáň fyziologie   chirurgie   MeSH
• Check Tag
• lidé MeSH

Suction lipectomy is a very effective and safe method, if performed by an experienced plastic surgeon. The authors demonstrate using a group of 284 patients operated on at the University Clinic of Plastic Surgery in Pra- gue between 1994-1998, indications, the method and complications.

• MeSH
• dospělí MeSH
• kvalita života MeSH
• lidé středního věku MeSH
• lidé MeSH
• lipektomie metody   normy   statistika a číselné údaje   MeSH
• obezita chirurgie   MeSH
• tuková tkáň chirurgie   MeSH
• výsledek terapie statistika a číselné údaje   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH

• MeSH
• dospělí MeSH
• lidé MeSH
• mnohočetná symetrická lipomatóza diagnóza   chirurgie   MeSH
• plastická chirurgie metody   MeSH
• tuková tkáň chirurgie   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH

• MeSH
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• lipektomie metody   MeSH
• mnohočetná symetrická lipomatóza etiologie   chirurgie   MeSH
• nádory hlavy a krku chirurgie   MeSH
• tuková tkáň chirurgie   metabolismus   MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH

• MeSH
• alkoholismus MeSH
• krk chirurgie   MeSH
• lipom chirurgie   MeSH
• tuková tkáň chirurgie   MeSH
• Publikační typ
• kazuistiky MeSH

• MeSH
• biomedicínský výzkum MeSH
• dermatochirurgické výkony MeSH
• kůže MeSH
• nemoci očních víček chirurgie   MeSH
• tuková tkáň chirurgie   MeSH