23 s. : il.
- MeSH
- Risk Assessment MeSH
- Permethrin MeSH
- Toxic Actions MeSH
- Environmental Exposure MeSH
- Environmental Pollution MeSH
- Publication type
- Guideline MeSH
- NML Fields
- toxikologie
- hygiena
Health and Safety Guide, ISSN 0259-7268 No. 33
31 s. : tab., lit.
- Conspectus
- Chemie. Mineralogické vědy
- NML Fields
- chemie, klinická chemie
- toxikologie
- NML Publication type
- publikace WHO
Environmental health criteria ; 94
125 s. : obr., tab.
- Conspectus
- Veřejné zdraví a hygiena
- NML Fields
- toxikologie
- environmentální vědy
- fyziologie
- NML Publication type
- publikace WHO
A new on-line SPE-HPLC method using fused-core columns for on-line solid phase extraction and large volume sample injection for increasing the sensitivity of detection was developed for the determination of insecticides fenoxycarb and cis-, trans-permethrin in surface waters. The separation was carried out on fused-core column Phenyl-Hexyl (100×4.6 mm), particle size 2.7 µm with mobile phase acetonitrile:water in gradient mode at flow rate 1.0 mL min(-1), column temperature 45°C. Large volume sample injection (1500 µL) to the extraction dimension using short precolumn Ascentis Express RP C-18 (5×4.6 mm); fused-core particle size 2.7 µm allowed effective sample preconcentration and efficient ballast sample matrix removal. The washing mobile phase consisting of a mixture of acetonitrile:water; 30:70, (v/v) was pumped at flow rate of 0.5 mL min(-1) through the extraction precolumn to the waste. Time of the valve switch for transferring the preconcentrated sample zone from the extraction to the separation column was set at 3rd min. Elution of preconcentrated insecticides from the extraction precolumn and separation on the analytical column was performed in gradient mode. Linear gradient elution started from 40% of acetonitrile at time of valve switch from SPE column (3rd min) to 95% of acetonitrile at 7th min. Synthetic dye sudan I was chosen as an internal standard. UV detection at wavelength 225 nm was used and the method reached the limits of detection (LOD) at ng mL(-1) levels for both insecticides. The method showing on-line sample pretreatment and preconcentration with highly sensitive determination of insecticides was applied for monitoring of fenoxycarb and both permethrin isomers in different surface water samples in Czech Republic. The time of whole analysis including on-line extraction, interferences removal, chromatography separation and system equilibration was less than 8 min.
- MeSH
- Water Pollutants, Chemical analysis MeSH
- Solid Phase Extraction MeSH
- Phenylcarbamates analysis MeSH
- Insecticides analysis MeSH
- Lakes analysis MeSH
- Environmental Monitoring MeSH
- Online Systems MeSH
- Permethrin analysis MeSH
- Rivers chemistry MeSH
- Chromatography, High Pressure Liquid MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
Svrab je epidemická ektoparazitóza vyvolaná zákožkou svrabovou. Zdrojem nákazy je nemocný člověk. K přenosu infekce dochází buď přímo, nebo nepřímo. Inkubační doba je 2–3 týdny. Onemocnění charakterizuje intenzivní noční pruritus. V dětském věku se toto onemocnění vyskytuje velmi často. Diagnostika choroby je založená na pozitivní anamnéze nočního pruritu, klinickém obraze a průkazu zákožky v kůži nemocného. Metodou první volby v terapii choroby u dětí je permethrin a síra. Svrab podléhá povinnému epidemiologickému hlášení. V článku popisujeme etiologii, patogenezi, diagnostiku, diferenciální diagnostiku a terapii choroby včetně současné legislativy a protiepidemických opatření.
Scabies is epidemic ectoparasitosis caused by human parasite Sarcoptes scabiei, var. hominis. The reservoir of a contagion is the man. The transmission of the disease is caused by direct or indirect contact. The incubation period ranges from two to three weeks. The disease is characterised by an intensive night pruritus. In childhood age we can find this disease very frequently. Diagnostics is based on positive night pruritus, clinical picture and demonstration of Sarcoptes scabiei in skin of ill person. The method of the first alternative at children there is permethrin and sulphur. Scabies is subordinated to the obligatory epidemiologic announcement. In the article we describe aetiology, pathogenesis, diagnostics, differential diagnostics, treatment and present legislation with precaution.
- MeSH
- Antiparasitic Agents administration & dosage MeSH
- Benzoates therapeutic use MeSH
- Diagnosis, Differential MeSH
- Child MeSH
- Hexachlorocyclohexane administration & dosage MeSH
- Disease Notification standards statistics & numerical data MeSH
- Ivermectin administration & dosage MeSH
- Humans MeSH
- Permethrin administration & dosage MeSH
- Sulfur therapeutic use MeSH
- Scabies * diagnosis drug therapy prevention & control transmission MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Publication type
- Review MeSH
