Biosensors using cholinesterases as the biorecognition component have been used to assay organophosphates and carbamates for a long time. In this review, some strategies convenient for biosensor construction are presented. Solutions for cholinesterase immobilization and output signal monitoring are presented as the basic presumptions for successful biosensor construction.

Center of Advanced Studies Faculty of Military Medicine University of Defense Hradec Kralove Czech Republic

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Cholinesterase based amperometric biosensors for assay of anticholinergic compounds

Evaluation of cholinesterase activities during in vivo intoxication using an electrochemical sensor strip - correlation with intoxication symptoms

Amperometric Biosensors for Real Time Assays of Organophosphates

Diagnosis of Intoxication by the Organophosphate VX: Comparison Between an Electrochemical Sensor and Ellman´s Photometric Method