Divergent mitochondrial respiratory chains in phototrophic relatives of apicomplexan parasites
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
Grantová podpora
Canadian Institutes of Health Research - Canada
PubMed
25660376
DOI
10.1093/molbev/msv021
PII: msv021
Knihovny.cz E-zdroje
- Klíčová slova
- Apicomplexa, Chromera, Vitrella, anaerobic metabolism, evolution, respiratory chain,
- MeSH
- Alveolata genetika metabolismus MeSH
- Apicomplexa genetika MeSH
- cytochromy c metabolismus MeSH
- fotosyntéza genetika MeSH
- fylogeneze * MeSH
- genetická variace * MeSH
- genom mitochondriální MeSH
- kyselina mléčná metabolismus MeSH
- mitochondriální protonové ATPasy genetika metabolismus MeSH
- mitochondrie genetika metabolismus MeSH
- molekulární evoluce * MeSH
- paraziti genetika metabolismus MeSH
- respirační komplex I genetika metabolismus MeSH
- transport elektronů MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- cytochromy c MeSH
- kyselina mléčná MeSH
- mitochondriální protonové ATPasy MeSH
- respirační komplex I MeSH
Four respiratory complexes and ATP-synthase represent central functional units in mitochondria. In some mitochondria and derived anaerobic organelles, a few or all of these respiratory complexes have been lost during evolution. We show that the respiratory chain of Chromera velia, a phototrophic relative of parasitic apicomplexans, lacks complexes I and III, making it a uniquely reduced aerobic mitochondrion. In Chromera, putative lactate:cytochrome c oxidoreductases are predicted to transfer electrons from lactate to cytochrome c, rendering complex III unnecessary. The mitochondrial genome of Chromera has the smallest known protein-coding capacity of all mitochondria, encoding just cox1 and cox3 on heterogeneous linear molecules. In contrast, another photosynthetic relative of apicomplexans, Vitrella brassicaformis, retains the same set of genes as apicomplexans and dinoflagellates (cox1, cox3, and cob).
Citace poskytuje Crossref.org
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BioProject
PRJEB667, PRJEB6670
SRA
ERR558149, ERR558150, ERR558151, ERR558152, ERR558194, ERR558195, ERR558196, ERR558197, ERR558198, ERR558199, ERR558200, ERR558201, ERR558202, ERR571482, ERR571483, ERR571484, ERR571485
