The class Kinetoplastea encompasses both free-living and parasitic species from a wide range of hosts. Several representatives of this group are responsible for severe human diseases and for economic losses in agriculture and livestock. While this group encompasses over 30 genera, most of the available information has been derived from the vertebrate pathogenic genera Leishmaniaand Trypanosoma. Recent studies of the previously neglected groups of Kinetoplastea indicated that the actual diversity is much higher than previously thought. This article discusses the known segment of kinetoplastid diversity and how gene-directed Sanger sequencing and next-generation sequencing methods can help to deepen our knowledge of these interesting protists.

Biology Centre Institute of Parasitology Czech Academy of Sciences České Budejovice Czech Republic

Centre National de la Recherche Scientifique Muséum National d'Histoire Naturelle Sorbonne Universités Paris France

Laboratório de Estudos Integrados em Protozoologia Instituto Oswaldo Cruz Fundação Oswaldo Cruz Rio de Janeiro RJ Brasil

Life Science Research Centre University of Ostrava Ostrava Czech Republic

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Shining the spotlight on the neglected: new high-quality genome assemblies as a gateway to understanding the evolution of Trypanosomatidae

Distribution of Merlin in eukaryotes and first report of DNA transposons in kinetoplastid protists

Euglenozoa: taxonomy, diversity and ecology, symbioses and viruses

The Remarkable Metabolism of Vickermania ingenoplastis: Genomic Predictions

Vickermania gen. nov., trypanosomatids that use two joined flagella to resist midgut peristaltic flow within the fly host

First Draft Genome of the Trypanosomatid Herpetomonas muscarum ingenoplastis through MinION Oxford Nanopore Technology and Illumina Sequencing

If host is refractory, insistent parasite goes berserk: Trypanosomatid Blastocrithidia raabei in the dock bug Coreus marginatus

Trypanosomatid parasites in Austrian mosquitoes

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania

Molecular mechanisms of thermal resistance of the insect trypanosomatid Crithidia thermophila