The effect of ethylene oxide sterilization on electrospun vascular grafts made from biodegradable polyesters
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články
PubMed
30184736
DOI
10.1016/j.msec.2018.06.041
PII: S0928-4931(17)33882-1
Knihovny.cz E-zdroje
- Klíčová slova
- Ethylene oxide sterilization, Nanofibers, Polyesters, Vascular grafts,
- MeSH
- biokompatibilní materiály chemie metabolismus farmakologie MeSH
- buněčné linie MeSH
- cévní protézy MeSH
- ethylenoxid chemie farmakologie MeSH
- mikroskopie elektronová rastrovací MeSH
- modul pružnosti MeSH
- myši MeSH
- nanovlákna chemie MeSH
- pevnost v tahu MeSH
- polyestery chemie metabolismus MeSH
- sterilizace MeSH
- viabilita buněk účinky léků MeSH
- zvířata MeSH
- Check Tag
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- biokompatibilní materiály MeSH
- ethylenoxid MeSH
- poly(lactide) MeSH Prohlížeč
- polycaprolactone MeSH Prohlížeč
- polyestery MeSH
The study describes the detailed examination of the effect of ethylene oxide sterilization on electrospun scaffolds constructed from biodegradable polyesters. Different fibrous layers fabricated from polycaprolactone (PCL) and a copolymer consisting of polylactide and polycaprolactone (PLCL) were investigated for the determination of their mechanical properties, degradation rates and interaction with fibroblasts. It was discovered that the sterilization procedure influenced the mechanical properties of the electrospun PLCL copolymer scaffold to the greatest extent. No effect of ethylene oxide sterilization on degradation behavior was observed. However, a delayed fibroblast proliferation rate was noticed with concern to the ethylene oxide sterilized samples compared to the ethanol sterilization of the materials.
Citace poskytuje Crossref.org
Impact of Various Sterilization and Disinfection Techniques on Electrospun Poly-ε-caprolactone
