-
Autor
Ahmed, N 1 Ahmed, Niaz 1 Bigliardi, G 1 Bigliardi, Guido 1 Brozman, M 1 Brozman, Miroslav 1 Cavallo, R 1 Cavallo, Roberto 1 Dorado, L 1 Dorado, Laura 1 Dávalos, A 1 Dávalos, Antoni 1 Egido, J A 1 Egido, Jose A 1 Escudero-Martinez, I 1 Escudero-Martínez, Irene 1 Herzig, R 1 Herzig, Roman 1 Holmin, S 1 Holmin, Staffan 1
-
Pracoviště
Department of Human Neurosciences La ... 2 Department of Neurology Hospital Clín... 2 Department of Neurology Ospedale San ... 2 Department of Neurology Tampere Unive... 2 International Clinical Research Cente... 2 Stroke Unit Azienda Ospedaliera Unive... 2 Stroke Unit Hospital de São José Cent... 2 2nd Department of Neurology National ... 1 2nd Department of Neurology National ... 1 Constantine the Philosopher Universit... 1 Department of Biomedical Metabolical ... 1 Department of Biomedical Metabolical ... 1 Department of Clinical Neuroscience K... 1 Department of Clinical Neuroscience K... 1 Department of Neurology Cliniques Uni... 1 Department of Neurology Cliniques Uni... 1 Department of Neurology Comprehensive... 1 Department of Neurology Comprehensive... 1 Department of Neurology Helsinki Univ... 1 Department of Neurology Helsinki Univ... 1
- Formát
- Publikační typ
- Check Tag
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Dostupnost
- Vlastník
-
Autor
Ahmed, N 1 Ahmed, Niaz 1 Bigliardi, G 1 Bigliardi, Guido 1 Brozman, M 1 Brozman, Miroslav 1 Cavallo, R 1 Cavallo, Roberto 1 Dorado, L 1 Dorado, Laura 1 Dávalos, A 1 Dávalos, Antoni 1 Egido, J A 1 Egido, Jose A 1 Escudero-Martinez, I 1 Escudero-Martínez, Irene 1 Herzig, R 1 Herzig, Roman 1 Holmin, S 1 Holmin, Staffan 1
-
Pracoviště
Department of Human Neurosciences La ... 2 Department of Neurology Hospital Clín... 2 Department of Neurology Ospedale San ... 2 Department of Neurology Tampere Unive... 2 International Clinical Research Cente... 2 Stroke Unit Azienda Ospedaliera Unive... 2 Stroke Unit Hospital de São José Cent... 2 2nd Department of Neurology National ... 1 2nd Department of Neurology National ... 1 Constantine the Philosopher Universit... 1 Department of Biomedical Metabolical ... 1 Department of Biomedical Metabolical ... 1 Department of Clinical Neuroscience K... 1 Department of Clinical Neuroscience K... 1 Department of Neurology Cliniques Uni... 1 Department of Neurology Cliniques Uni... 1 Department of Neurology Comprehensive... 1 Department of Neurology Comprehensive... 1 Department of Neurology Helsinki Univ... 1 Department of Neurology Helsinki Univ... 1
- Formát
- Publikační typ
- Check Tag
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Dostupnost
- Vlastník
-
Ahmed, Niaz
Autor Ahmed, Niaz From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden. niaz.ahmed@ki.se
-
Mazya, Michael
Autor Mazya, Michael From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Nunes, Ana Paiva
Autor Nunes, Ana Paiva From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Moreira, Tiago
Autor Moreira, Tiago From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Ollikainen, Jyrki P
Autor Ollikainen, Jyrki P From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Escudero-Martínez, Irene
Autor Escudero-Martínez, Irene From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Bigliardi, Guido
Autor Bigliardi, Guido From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Dorado, Laura
Autor Dorado, Laura From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Dávalos, Antoni
Autor Dávalos, Antoni From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
-
Egido, Jose A
Autor Egido, Jose A From the Department of Neurology (N.A., M.M., T.M.), Karolinska University Hospital Department of Clinical Neuroscience (N.A., M.M., T.M., S.H.), Karolinska Institutet, Solna, Sweden Stroke Unit (A.P.N.), Hospital de São José, Centro Hospitalar Universitário de Lisboa Central, Lisboa, Portugal Department of Neurology (J.P.O.), Tampere University Hospital, Tampere, Finland Department of Neurology (I.E.-M.), University Hospital Virgen del Rocío, Sevilla and Biomedicine Institute of Sevilla, Spain Department of Neurology (G.B.), Ospedale Civile "S.Agostino-Estense"-Azienda Ospedaliera Universitaria di Modena, Italy Department of Neurology (L.D., A.D.), Hospital Universitari Germans Trias i Pujol, Badalona Department of Neurology (J.A.E.), Hospital Clínico San Carlos, Madrid, Spain Stroke Unit Azienda Ospedaliera Universitaria Senese (R.T.), Siena, Italy Department of Neurology (D.S.), Helsinki University Central Hospital, Finland IRCCS Istituto delle Scienze Neurologiche di Bologna (A.Z.), Department of Neurology and Stroke Center, Maggiore Hospital Department of Biomedical (P.N.), Metabolical and Neurosciences, Università degli studi di Modena e Reggio Emilia, Italy Department of Neurology (R.H.), Comprehensive Stroke Centre, Charles University, Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, Czech Republic Neurocentre (L.J.), Regional Hospital Liberec, Czech Republic Department of Neurology University Hospital Ostrava (E.H.), Czech Republic Second Department of Neurology (G.T., A.P.), National and Kapodistrian University of Athens, Greece Department of Neurology (G.T., A.P.), Cliniques Universitaires St-Luc, Brussels Department of Neurology (M.N.), Nemocnice Ceske Budejovice, Czech Republic Constantine the Philosopher University Nitra (M.B.), Faculty of Social Sciences and Health, Slovakia Department of Neurology (R.C.), Ospedale San Giovanni Bosco, Turin, Italy School of Medicine (K.R.L.), Dentistry and Nursing, University of Glasgow, UK International Clinical Research Center and Department of Neurology (R.M.), St. Anne's University Hospital and Masaryk University, Brno, Czech Republic Department of Human Neurosciences (D.T.), La Sapienza, Rome, Italy and Department of Neuroradiology (S.H.), Karolinska University Hospital, Solna, Sweden
OBJECTIVE: To test the hypothesis that IV thrombolysis (IVT) treatment before endovascular thrombectomy (EVT) is associated with better outcomes in patients with anterior circulation large artery occlusion (LAO) stroke, we examined a large real-world database, the Safe Implementation of Treatment in Stroke-International Stroke Thrombectomy Register (SITS-ISTR). METHODS: We identified centers recording ≥10 consecutive patients in the SITS-ISTR, with at least 70% available modified Rankin Scale (mRS) scores at 3 months during 2014 to 2019. We defined LAO as intracranial internal carotid artery, first and second segment of middle cerebral artery, and first segment of anterior cerebral artery. Main outcomes were functional independence (mRS score 0-2) and death at 3 months and symptomatic intracranial hemorrhage (SICH) per modified SITS-Monitoring Study. We performed propensity score-matched (PSM) and multivariable logistic regression analyses. RESULTS: Of 6,350 patients from 42 centers, 3,944 (62.1%) received IVT. IVT + EVT-treated patients had less frequent atrial fibrillation, ongoing anticoagulation, previous stroke, heart failure, and prestroke disability. PSM analysis showed that IVT + EVT-treated patients had a higher rate of functional independence than patients treated with EVT alone (46.4% vs 40.3%, p < 0.001) and a lower rate of death at 3 months (20.3% vs 23.3%, p = 0.035). SICH rates (3.5% vs 3.0%, p = 0.42) were similar in both groups. Multivariate adjustment yielded results consistent with PSM. CONCLUSION: Pretreatment with IVT was associated with favorable outcomes in EVT-treated LAO stroke in the SITS-ISTR. These findings, while indicative of international routine clinical practice, are limited by observational design, unmeasured confounding, and possible residual confounding by indication. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that IVT before EVT increases the probability of functional independence at 3 months compared to EVT alone.
- MeSH
- arteriae cerebrales diagnostické zobrazování patologie MeSH
- arteriální okluzní nemoci komplikace diagnostické zobrazování MeSH
- funkční status * MeSH
- hodnocení výsledků zdravotní péče * MeSH
- ischemická cévní mozková příhoda farmakoterapie etiologie terapie MeSH
- kombinovaná terapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- registrace statistika a číselné údaje MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- trombektomie statistika a číselné údaje MeSH
- trombolytická terapie statistika a číselné údaje MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
PubMed
33999451
DOI
10.1111/joim.13302
Knihovny.cz E-zdroje
BACKGROUND AND OBJECTIVE: We aimed to evaluate the safety and outcomes of thrombectomy in anterior circulation acute ischaemic stroke recorded in the SITS-International Stroke Thrombectomy Register (SITS-ISTR) and compare them with pooled randomized controlled trials (RCTs) and two national registry studies. METHODS: We identified centres recording ≥10 consecutive patients in the SITS-ISTR with at least 70% of available modified Rankin Scale (mRS) at 3 months during 2014-2019. We defined large artery occlusion as intracranial internal carotid artery, first and second segment of middle cerebral artery and first segment of anterior cerebral artery. Outcome measures were functional independence (mRS score 0-2) and death at 3 months and symptomatic intracranial haemorrhage (SICH) per modified SITS-MOST. RESULTS: Results are presented in the following order: SITS-ISTR, RCTs, MR CLEAN Registry and German Stroke Registry (GSR). Median age was 73, 68, 71 and 75 years; baseline NIHSS score was 16, 17, 16 and 15; prior intravenous thrombolysis was 62%, 83%, 78% and 56%; onset to reperfusion time was 289, 285, 267 and 249 min; successful recanalization (mTICI score 2b or 3) was 86%, 71%, 59% and 83%; functional independence at 3 months was 45.5% (95% CI: 44-47), 46.0% (42-50), 38% (35-41) and 37% (35-41), respectively; death was 19.2% (19-21), 15.3% (12.7-18.4), 29.2% (27-32) and 28.6% (27-31); and SICH was 3.6% (3-4), 4.4% (3.0-6.4), 5.8% (4.7-7.1) and not available. CONCLUSION: Thrombectomy in routine clinical use registered in the SITS-ISTR showed safety and outcomes comparable to RCTs, and better functional outcomes and lower mortality than previous national registry studies.
- MeSH
- arterie MeSH
- cévní mozková příhoda * MeSH
- endovaskulární výkony MeSH
- intrakraniální krvácení MeSH
- ischemie mozku * chirurgie MeSH
- lidé MeSH
- randomizované kontrolované studie jako téma MeSH
- retrospektivní studie MeSH
- trombektomie * MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- pozorovací studie MeSH
- práce podpořená grantem MeSH
Sdílet
Název dokumentu
Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.