Metallic biomaterial alloys composed of nickel and titanium have unique thermal shape memory, superelastic, and high damping properties, which are widely used in the medicine. The major parameter evaluated in the studies regarding the behaviour of the material in the contact with organism or cells is biocompatibility. The aim of the studies is to clarify the differences in the proliferation, growth, and morphology especially in the cell cultures. The cytotoxicity is affected among other by release of the metal ions in the presence of the metal alloy, which is further dependent on the possible treatments of the material and the corrosive properties. To evaluate the cytotoxicity, wide range of tests including the Sulforhodamine B assay and MTT tests, expression profiles, cell survival tests such as apoptotic test are used. The review compares the cell behaviour in contact with the material alloys composed of nickel and titanium with respect to different materials composition and different surface treatment that affects the ion release. Even though the results published so far are controversial, almost all data suggest sufficient biocompatibility in medical use.
- MeSH
- apoptóza účinky léků MeSH
- biokompatibilní materiály chemie farmakologie MeSH
- endoteliální buňky pupečníkové žíly (lidské) cytologie účinky léků fyziologie MeSH
- kmenové buňky cytologie účinky léků fyziologie MeSH
- krysa rodu rattus MeSH
- kultivované buňky MeSH
- lidé MeSH
- myocyty hladké svaloviny cytologie účinky léků fyziologie MeSH
- nádorové buněčné linie MeSH
- nikl chemie farmakologie MeSH
- proliferace buněk účinky léků MeSH
- rhodaminy chemie MeSH
- titan chemie farmakologie MeSH
- tuková tkáň cytologie účinky léků fyziologie MeSH
- viabilita buněk účinky léků MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
Alzheimer's disease is an incurable state that causes gradual loss of all mental functions. It affects all population groups. The disease brings suffering not only to the patients but also to their relatives. It also presents a great financial burden to the health care system.
Each of us can help visually impaired people to have their life easier. It is necessary that visually handicapped people know about and can use the professional services and special equipment that could increase their life quality. Independence will lead to higher self - consciousness and visually handicapped and it will allow them live more fully with the handicap.
- MeSH
- lidé MeSH
- pomůcky pro sebeobsluhu ekonomika MeSH
- postižení rehabilitace MeSH
- věnování darů MeSH
- Check Tag
- lidé MeSH
