• MeSH
• biologická adaptace MeSH
• cvičení * fyziologie   MeSH
• energetický metabolismus fyziologie   MeSH
• kosterní svalová vlákna fyziologie   metabolismus   MeSH
• lidé MeSH
• metabolismus lipidů MeSH
• metabolismus sacharidů MeSH
• oxidativní fosforylace MeSH
• tělesná námaha fyziologie   MeSH
• tělesná výkonnost fyziologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• přehledy MeSH

Molecular hydrogen (H2) is potentially a novel therapeutic gas for acute post-coronavirus disease 2019 (COVID-19) patients because it has antioxidative, anti-inflammatory, anti-apoptosis, and antifatigue properties. The aim of this study was to determine the effect of 14 days of H2 inhalation on the respiratory and physical fitness status of acute post-COVID-19 patients. This randomized, single-blind, placebo-controlled study included 26 males (44 ± 17 years) and 24 females (38 ± 12 years), who performed a 6-min walking test (6 MWT) and pulmonary function test, specifically forced vital capacity (FVC) and expiratory volume in the first second (FEV1). Symptomatic participants were recruited between 21 and 33 days after a positive polymerase chain reaction test. The experiment consisted of H2/placebo inhalation, 2 × 60 min/day for 14 days. Results showed that H2 therapy, compared with placebo, significantly increased 6 MWT distance by 64 ± 39 m, FVC by 0.19 ± 0.24 L, and, in FEV1, by 0.11 ± 0.28 L (all p ≤ 0.025). In conclusion, H2 inhalation had beneficial health effects in terms of improved physical and respiratory function in acute post-COVID-19 patients. Therefore, H2 inhalation may represent a safe, effective approach for accelerating early function restoration in post-COVID-19 patients.

• MeSH
• COVID-19 * MeSH
• jednoduchá slepá metoda MeSH
• lidé MeSH
• respirační funkční testy MeSH
• SARS-CoV-2 MeSH
• usilovný výdechový objem MeSH
• vodík terapeutické užití   MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• randomizované kontrolované studie MeSH

ABSTRACT: Botek, M, Krejčí, J, McKune, A, Valenta, M, and Sládečková, B. Hydrogen rich water consumption positively affects muscle performance, lactate response, and alleviates delayed onset of muscle soreness after resistance training. J Strength Cond Res 36(10): 2792-2799, 2022-Positive outcomes of hydrogen rich water (HRW) supplementation on endurance performance have been shown, but the effects of HRW in resistance training are unclear. The aim of this study was to assess the effects of 1,260 ml of HRW intake on physiological, perceptual, and performance responses to a resistance training and after 24 hours of recovery. This randomized, double-blinded placebo-controlled cross-over study included 12 men aged 23.8 ± 1.9 years. Subjects performed a half squat, knee flexion, and extension exercises with the load set at 70% of 1 repetition maximum for 3 sets (10 reps/set). Lunges were performed with a load of 30% of body mass for 3 sets (20 reps/set). Time of each set, lactate, and ratings of perceived exertion were assessed mid-way through exercise and immediately after the exercise. Creatine kinase, muscle soreness visual analog scale ratings, countermovement jump, and heart rate variability were evaluated before the training and at 30 minutes, 6, and 24 hours of recovery. Lunges were performed faster with HRW compared with placebo ( p < 0.001). Hydrogen rich water reduced lactate at mid-way and immediately after the exercise (HRW: 5.3 ± 2.1 and 5.1 ± 2.2, placebo: 6.5 ± 1.8 and 6.3 ± 2.2 mmol·L -1 , p ≤ 0.008). Visual analog scale ratings were significantly lower with HRW (26 ± 11 vs. 41 ± 20 mm, p = 0.002) after 24 hours of recovery. In conclusion, an acute intermittent HRW hydration improved muscle function, reduced the lactate response, and alleviated delayed onset of muscle soreness.

• MeSH
• klinické křížové studie MeSH
• kosterní svaly fyziologie   MeSH
• kreatinkinasa, forma MM MeSH
• kyselina mléčná MeSH
• lidé MeSH
• myalgie prevence a kontrola   MeSH
• odporový trénink * MeSH
• pití MeSH
• svalová síla fyziologie   MeSH
• svaly MeSH
• voda MeSH
• vodík MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• randomizované kontrolované studie MeSH

Hydrogen-rich water (HRW) supplementation has been shown to have an antifatigue effect across different modes of exercise. However, its effect on repeated sprint performance is unknown. The aim of this study was to assess the effect of pre-exercise HRW consumption on repeated sprint performance, lactate, and perceptual responses using a repeated sprint protocol. This randomized, double blinded, placebo controlled, crossover study included 16 professional, male soccer players aged 18.8 ± 1.2 years. Athletes performed two indoor tests, particularly 15 × 30 m track sprints interspersed by 20 s of recovery, separated by a 1-week washout period. Sprint time was measured at 15 m and 30 m. Ratings of perceived exertion were assessed immediately after each sprint, and post-exercise blood lactate concentration was measured after the last sprint. There were significantly faster sprint times after HRW consumption compared with placebo at 15 m for the 14th and 15th sprints, representing improvements in time of 3.4% and 2.7%, respectively. Sprint time at 30 m also significantly improved by 1.9% in the HRW group in the last sprint. However, neither lactate concentrations nor ratings of perceived exertion were significantly different between HRW and placebo. Pre-exercise HRW supplementation is associated with an increased ability to reduce fatigue, especially during the later stages of repeated sprint exercise.

• MeSH
• běh * fyziologie   MeSH
• dospělí MeSH
• fotbal * fyziologie   MeSH
• klinické křížové studie MeSH
• kyselina mléčná MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• sportovní výkon * fyziologie   MeSH
• vodík MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• randomizované kontrolované studie MeSH

Background: Hydrogen-rich water (HRW) has been shown to have a stimulating effect on the human body. Objective: The aim of the study was to assess the influence of acute HRW intake on autonomic cardiac regulation during 50 min of rest sitting. Methods: Fourteen healthy females (age 21.7 ± 1.2 years, body mass 67.8 ± 8.7 kg, height 167 ± 5.5 cm) took part in this double-blind, randomized, placebo-controlled trial with crossover design. Heart rate variability (HRV) was monitored in the sitting position after administration of 1260 ml of HRW or placebo. Time domain indexes of HRV as the square root of the mean of the squares of differences between adjacent RR intervals (RMSSD), the standard deviation of all RR intervals (SDNN) and the ratio of SDNN/RMSSD as an index of sympatho-vagal balance were used to assess autonomic cardiac response. The values were transformed using natural logarithm (Ln). Results: After administration of HRW, we found significantly increased ratio Ln SDNN/RMSSD when comparing it to placebo in 25 min (HRW: 0.40 ± 0.30, placebo: 0.26 ± 0.25, p = .049) and 35 min (HRW: 0.44 ± 0.30, placebo: 0.28 ± 0.28, p = .029) of rest sitting. Ln SDNN was significantly increased after HRW administration when compared to placebo in 45 min (HRW: 4.41 ± 0.42 ms, placebo: 4.28 ± 0.31 ms, p = .049) of rest sitting. Conclusions: Acute HRW ingestion induced a relative increase in sympathetic activity between 25 and 35 min post-ingestion, whereas vagal activity was not affected.

• Klíčová slova
• vodíková voda,
• MeSH
• autonomní nervový systém * MeSH
• klinická studie jako téma MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• sympatický nervový systém MeSH
• voda MeSH
• vodík * MeSH
• Check Tag
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• ženské pohlaví MeSH

• Publikační typ
• abstrakt z konference MeSH

The potential anti-fatigue and performance benefits of hydrogen rich water (HRW) have resulted in increased research interest over the past 5 years. The aim of this study was to assess physiological and perceptual responses to an incremental exercise protocol after administration of 600 ml HRW within 30 min before exercise. This randomized, double blinded placebo-controlled cross over study included twelve healthy males aged 27.1±4.9 years. The exercise protocol consisted of a 10 min warm-up at 1.0 W.kg-1, followed by 8 min at 2.0, 3.0, and 4.0 W.kg-1, respectively. Cardio-respiratory variables, lactate and ratings of perceived exertion (RPE) were assessed in the last minute of each step. A significantly lower blood lactate was found with HRW (4.0±1.6 and 8.9±2.2 mmol.l-1) compared to Placebo (5.1±1.9 and 10.6±3.0 mmol.l-1) at 3.0, and 4.0 W.kg-1, respectively. Ventilatory equivalent for oxygen and RPE exhibited significantly lower values with HRW (32.3±7.2, and 17.8±1.2 points, respectively) compared to Placebo (35.0±8.4, and 18.5±0.8 points, respectively) at 4 W.kg-1. To conclude, acute pre-exercise supplementation with HRW reduced blood lactate at higher exercise intensities, improved exercise-induced perception of effort, and ventilatory efficiency.

• MeSH
• cvičení fyziologie   psychologie   MeSH
• dospělí MeSH
• dvojitá slepá metoda MeSH
• dýchání * MeSH
• kyselina mléčná krev   MeSH
• lidé MeSH
• mladý dospělý MeSH
• percepce fyziologie   MeSH
• pití * MeSH
• spotřeba kyslíku fyziologie   MeSH
• srdeční frekvence fyziologie   MeSH
• svalová únava fyziologie   MeSH
• tělesná námaha fyziologie   MeSH
• voda chemie   MeSH
• vodík * MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• randomizované kontrolované studie MeSH

Introduction: The main aims of this study were to investigate autonomic nervous system (ANS) and arterial oxygen saturation (SpO2) responses to simulated altitude in males and females, and to determine the association between maximal oxygen uptake (VO2max) and these responses. Materials and Methods: Heart rate variability (HRV) and SpO2 were monitored in a resting supine position during Preliminary (6 min normoxia), Hypoxia (10 min, fraction of inspired oxygen (FiO2) of 9.6%, simulated altitude ~6,200 m) and Recovery (6 min normoxia) phases in 28 males (age 23.7 ± 1.7 years, normoxic VO2max 59.0 ± 7.8 ml.kg-1.min-1, body mass index (BMI) 24.2 ± 2.1 kg.m-2) and 30 females (age 23.8 ± 1.8 years, VO2max 45.1 ± 8.7 ml.kg-1.min-1, BMI 21.8 ± 3.0 kg.m-2). Spectral analysis of HRV quantified the ANS activity by means of low frequency (LF, 0.05-0.15 Hz) and high frequency (HF, 0.15-0.50 Hz) power, transformed by natural logarithm (Ln). Time domain analysis incorporated the square root of the mean of the squares of the successive differences (rMSSD). Results: There were no significant differences in SpO2 level during hypoxia between the males (71.9 ± 7.5%) and females (70.8 ± 7.1%). Vagally-related HRV variables (Ln HF and Ln rMSSD) exhibited no significant differences between sexes across each phase. However, while the sexes demonstrated similar Ln LF/HF values during the Preliminary phase, the males (0.5 ± 1.3) had a relatively higher (p = 0.001) sympathetic activity compared to females (-0.6 ± 1.4) during the Hypoxia phase. Oxygen desaturation during resting hypoxia was significantly correlated with VO2max in males (r = -0.45, p = 0.017) but not in females (r = 0.01, p = 0.952) and difference between regression lines were significant (p = 0.024). Conclusions: Despite similar oxygen desaturation levels, males exhibited a relatively higher sympathetic responses to hypoxia exposure compared with females. In addition, the SpO2 response to resting hypoxia exposure was related to maximal aerobic capacity in males but not females.

• Publikační typ
• časopisecké články MeSH

Cílem publikace je nabídnout základní a rozšiřující výukový materiál, který bude nápomocen při přípravě na zkoušky z předmětů s náplní fyziologie člověka v bakalářské a magisterské etapě studia.

• MeSH
• energetický metabolismus MeSH
• fyziologie MeSH
• neurofyziologie MeSH

• Konspekt
• Fyziologie člověka a srovnávací fyziologie
• Učební osnovy. Vyučovací předměty. Učebnice
• NLK Obory
• fyziologie
• NLK Publikační typ
• učebnice vysokých škol

V současnosti existuje mnoho metod, jak posoudit prostřednictvím variability srdeční frekvence (VSF) funkční změny autonomního nervového systému (ANS), který se v organismu podílí na kontrole a regulaci homeostázy. VSF reprezentuje moderní diagnostický přístup, jak objektivně zmonitorovat odezvu organismu na tréninkové i mimotréninkové stresové podněty (např. na psychosociální stres nebo environmentální vlivy). Longitudinální sledování VSF během tréninkového procesu umožňuje sportovci nebo trenérovi operativně měnit velikost zatížení s ohledem na aktuální stav tréninkové kapacity jeho organismu – adaptability, a tím maximalizovat tréninkový efekt. Navíc se díky této pravidelné kontrole snižuje riziko kumulované únavy nebo vzniku přetrénování. Analýza VSF se tak stává přirozenou součástí tréninkového procesu, která nabízí i v kolektivních sportech maximální možnou míru individualizace. Nakladatelská anotace; V současnosti existuje mnoho metod, jak posoudit prostřednictvím variability srdeční frekvence (VSF) funkční změny autonomního nervového systému, který se v organismu podílí na kontrole a regulaci homeostázy. VSF reprezentuje moderní diagnostický přístup, jak objektivně zmonitorovat odezvu organismu na tréninkové i mimotréninkové stresové podněty. Longitudinální sledování VSF během tréninkového procesu umožňuje sportovci nebo trenérovi operativně měnit zatížení s ohledem na aktuální stav tréninkové kapacity jeho organismu a tím maximalizovat tréninkový efekt. Navíc se díky této pravidelné kontrole snižuje riziko kumulované únavy nebo přetrénování. Analýza VSF se tak stává přirozenou součástí tréninkového procesu, která nabízí i v kolektivních sportech maximální možnou míru individualizace.

• MeSH
• autonomní nervový systém MeSH
• elektrodiagnostika MeSH
• neurofyziologie MeSH
• sporty MeSH
• srdeční frekvence MeSH
• tělovýchovné lékařství * MeSH

• Konspekt
• Fyziologie člověka a srovnávací fyziologie
• NLK Obory
• tělovýchovné lékařství
• NLK Publikační typ
• kolektivní monografie