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Male infertility affects nearly 14% of men in Europe, and approximately 44% of them are unaware of the cause of their infertility. Thanks to the plentitude of research, we can now clearly define the risk factors that negatively affect semen quality, including substance abuse. The research objective seeks to determine whether these risk factors are present in candidate sperm donors in the clinics of reproductive medicine in the Moravian region and how they influence their spermiogram (SPG) values. METHODS: The lifestyle of candidate sperm donors will be monitored by a self-assessment questionnaire asking about dietary habits, physical activity, abusive behaviour including smoking habits, and alcohol and drug use. The SPG values will be evaluated according to the WHO manual from 2010. Moreover, the contents of potentially toxic elements in the seminal fluid will be determined using atomic absorption spectrometry. RESULTS: Although the candidate sperm donors are young and healthy men aged 18–35, not everyone is classified as the normozoospermic, a prerequisite of acceptance into the donor program. CONCLUSIONS: The study will provide the specific profile of lifestyle habits, including abusive behaviour in candidate sperm donors. The results will be published in a peer- reviewed journal. We will be able to identify potential risk factors of lifestyle habits that negatively affect the quality of semen and thus increase the possibility of accepting young men into the donor programme.
OBJECTIVES: Overweight and obesity are risk factors for many diseases, nutrition leading to these phenomena is not only a question of disbalance between energy intake and expenditure, but also the presence of micronutrients. In our study, we focused on measuring residues of chromium, zinc and iron in the hair of men with different BMI. METHODS: Hair samples and anthropometric questionnaires were collected from 45 males. Numbers of subjects and age structure were comparable between the three BMI groups. The determination of metal levels was performed by inductively coupled plasma mass spectrometry after mineralization of the hair. RESULTS: The hair of obese men contained significantly higher chromium (0.096 μg/g vs. 0.045 μg/g, p = 0.0039) and iron (9.42 μg/g vs. 5.84 μg/g, p = 0.0009) concentrations than that of overweight men, but no significant difference between the normal-weight group and the obese group were found. The concentration of zinc was lower in obese subjects compared to overweight subjects (183.5 μg/g vs. 206.2 μg/g, p = 0.038). Also, statistically significant correlations between chromium and iron concentrations in hair and BMI were found (r = 0.307, p = 0.040, r = 0.360, p = 0.015, respectively). According to our results, age did not significantly affect chromium, iron and zinc concentrations in hair. CONCLUSION: Consistent with some published studies, we have found that obese men have higher chromium and iron concentrations and lower zinc concentrations in hair.
- MeSH
- chrom MeSH
- lidé MeSH
- nadváha * MeSH
- obezita epidemiologie MeSH
- vlasy, chlupy * MeSH
- zinek MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- fyziologie výživy MeSH
- kyselina oxalová MeSH
- lidé MeSH
- nutriční hodnota MeSH
- Rheum * MeSH
- vaření MeSH
- Check Tag
- lidé MeSH
- MeSH
- aminokyseliny MeSH
- analýza potravin MeSH
- Lactobacillus helveticus MeSH
- potravinářský průmysl metody MeSH
- potraviny MeSH
- sýr * MeSH
- Publikační typ
- přehledy MeSH