Q95156976
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Kazuistika popisuje případ pacienta s hereditárním deficitem C1 inhibitoru, který se iniciálně prezentoval obrazem ileo- kolitidy. Diagnóza byla laboratorně potvrzena 0% funkční aktivitou C1 inhibitoru, byla zahájena terapie antagonistou B2 receptoru s dobrým efektem.
Our case study presents patient with C1 esterase inhibitor deficiency, whose first manifestation was due to abdominal colic. Our diagnosis was confirmed by assessing the C1INH levels and C1INH functional deficit. Therapy was started with B2 receptor antagonist Icatibant with promising result.
- MeSH
- angioedém diagnóza etiologie farmakoterapie MeSH
- antagonisté bradykininového receptoru B2 aplikace a dávkování terapeutické užití MeSH
- hereditární angioedémy * diagnóza farmakoterapie MeSH
- imunologické testy MeSH
- komplement C1 - inaktivátory MeSH
- lidé MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
BACKGROUND: COPD is a glo Bal concern. Currently, several sets of guidelines, statements and strategies to managing COPD exist around the world. METHODS: The Czech Pneumological and Phthisiological Society (CPPS) has commissioned an Expert group to draft recommended guidelines for the management of sta Ble COPD. Su Bsequent revisions were further discussed at the National Consensus Conference (NCC). Reviewers' comments contri Buted to the esta Blishment of the document's final version. DIAGNOSIS: The hallmark of the novel approach to COPD is the integrated evaluation of the patient's lung functions, symptoms, exacer Bations and identifications of clinical phenotype(s). The CPPS defines 6 clinically relevant phenotypes: frequent exacer Bator, COPD-asthma overlap, COPD- Bronchiectasis overlap, emphysematic phenotype, Bronchitic phenotype and pulmonary cachexia phenotype. TREATMENT: Treatment recommendations can Be divided into four steps. 1(st) step = Risk exposure elimination: reduction of smoking and environmental to Bacco smoke (ETS), decrease of home and occupational exposure risks. 2(nd) step = Standard treatment: inhaled Bronchodilators, regular physical activity, pulmonary reha Bilitation, education, inhalation training, comor Bidity treatment, vaccination. 3(rd) step = Phenotype-specific therapy: PDE4i, ICS+LA BA, LVRS, BVR, AAT augmentation, physiotherapy, mucolytic, A BT. 4(th) step = Care for respiratory insufficiency and terminal COPD: LTOT, lung transplantation, high intensity-NIV and palliative care. CONCLUSION: Optimal treatment of COPD patients requires an individualised, multidisciplinary approach to the patient's symptoms, clinical phenotypes, needs and wishes. The new Czech COPD guideline reflects and covers these requirements.
- MeSH
- chronická obstrukční plicní nemoc klasifikace diagnóza terapie MeSH
- konsensus MeSH
- lidé MeSH
- péče orientovaná na pacienta MeSH
- plánování péče o pacienty MeSH
- pneumologie MeSH
- společnosti lékařské MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- směrnice pro lékařskou praxi MeSH
- Geografické názvy
- Česká republika MeSH
- MeSH
- dospělí MeSH
- echokardiografie transezofageální metody využití MeSH
- hypertrofická kardiomyopatie diagnóza ultrasonografie MeSH
- hypertrofie levé komory srdeční diagnóza MeSH
- koronární angiografie metody využití MeSH
- troponin izolace a purifikace MeSH
- ženy MeSH
- Check Tag
- dospělí MeSH
- Publikační typ
- kazuistiky MeSH
Snake bites caused by viperid snakes of Atheris genus are extremely rare, envenoming of a bite of related viper Proatheris superciliaris was described only once in the literature. The present case study depicts the envenoming of a 57 years old Czech man, a private herpetologist, who was bitten to his finger. He developed painful local reaction, nausea, hematuria, hypertension, chest and lumbar pain. Coagulopathy and thrombocytopenia subsequently developed as well as acute renal failure, hepatic and lung lesion. Intensive care therapy was purely symptomatic and supportive as no antisera exists. Treatment included haemodialysis, substitution of fresh frozen plasma and platelets. Patient completely recovered during 1 month.
- MeSH
- akutní poškození ledvin etiologie patologie terapie MeSH
- dialýza ledvin MeSH
- jedy chřestýšů toxicita MeSH
- koagulopatie etiologie patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- prsty ruky patologie MeSH
- transfuze trombocytů MeSH
- trombocytopenie etiologie patologie MeSH
- uštknutí hadem komplikace patologie terapie MeSH
- Viperidae MeSH
- výsledek terapie MeSH
- zvířata MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- kazuistiky MeSH
