In recent decades, the non-thermal plasma, i.e. partially or completely ionized gas produced by electric discharges at ambient temperature, has become of interest for its microbiocidal properties with potential of use in the food industry or medicine. Recently, this interest focuses not only on the planktonic forms of microorganisms but also on their biofilms. The works in this interdisciplinary field are summarized in this review. The wide range of biofilm-plasma interactions is divided into studies of general plasma action on bacteria, on biofilm and on its oral and dental application; a short overview of plasma instrumentation is also included. In addition, not only biofilm combating but also an important area of biofilm prevention is discussed. Various DC discharges of the point-to-plane type. Author's photograph, published in Khun et al. (Plasma Sources Sci Technol 27:065002, 2018).

Department of Biotechnology University of Chemistry and Technology Technická 5 166 28 Prague 6 Czech Republic

Department of Physics and Measurements University of Chemistry and Technology Technická 5 166 28 Prague 6 Czech Republic

Institute of Immunology and Microbiology 1st Faculty of Medicine Charles University and General University Hospital Studničkova 7 128 00 Prague 2 Czech Republic

Zobrazit více v PubMed

J Dtsch Dermatol Ges. 2010 Dec;8(12):968-76 PubMed

Folia Microbiol (Praha). 2011 Jan;56(1):77-9 PubMed

J Med Microbiol. 2010 Feb;59(Pt 2):206-12 PubMed

Trends Biotechnol. 2018 Jun;36(6):627-638 PubMed

Expert Rev Med Devices. 2013 May;10(3):367-77 PubMed

PLoS One. 2015 Jun 26;10(6):e0130373 PubMed

Anticancer Agents Med Chem. 2018;18(6):815-823 PubMed

IEEE Trans Plasma Sci IEEE Nucl Plasma Sci Soc. 2010 Dec 1;38(12):3398-3403 PubMed

J Cell Biol. 1997 Nov 3;139(3):729-34 PubMed

Biophys Rev. 2017 Dec;9(6):895-917 PubMed

J Appl Microbiol. 2017 Aug;123(2):308-324 PubMed

Front Cell Infect Microbiol. 2017 Feb 22;7:43 PubMed

Trends Biotechnol. 2018 Jun;36(6):583-585 PubMed

Biotechnol Adv. 2015 Nov 1;33(6 Pt 2):1108-19 PubMed

J Gen Physiol. 1957 Nov 20;41(2):359-81 PubMed

J Appl Microbiol. 2017 May;122(5):1134-1148 PubMed

Cell Death Differ. 2010 May;17(5):763-73 PubMed

Biomaterials. 2016 Mar;82:71-83 PubMed

Sci Total Environ. 2018 Aug 1;631-632:298-307 PubMed

Trends Biotechnol. 2018 Jun;36(6):586-593 PubMed

Int J Oral Sci. 2015 Mar 23;7(1):1-7 PubMed

Biomol Ther (Seoul). 2014 Nov;22(6):477-90 PubMed

J Med Microbiol. 2011 Jan;60(Pt 1):75-83 PubMed

Acta Odontol Scand. 2014 Jan;72(1):1-12 PubMed

New J Phys. 2011 Oct;13:null PubMed

PLoS One. 2015 Sep 21;10(9):e0138209 PubMed

J Hosp Infect. 2011 Jul;78(3):204-7 PubMed

GMS Hyg Infect Control. 2014 Sep 30;9(3):Doc17 PubMed

World J Microbiol Biotechnol. 2018 Sep 10;34(10):143 PubMed

Int Endod J. 2013 Oct;46(10):930-7 PubMed

PLoS One. 2012;7(7):e40629 PubMed

Surg Infect (Larchmt). 2014 Jun;15(3):233-43 PubMed

Tumour Biol. 2016 Jun;37(6):7021-31 PubMed

Biomed Res Int. 2017;2017:6085741 PubMed

Colloids Surf B Biointerfaces. 2017 Apr 1;152:354-366 PubMed

J Microbiol Methods. 2015 Dec;119:53-8 PubMed

J Endod. 2013 Jan;39(1):105-10 PubMed

GMS Hyg Infect Control. 2013 Apr 29;8(1):Doc01 PubMed

Skin Pharmacol Physiol. 2014;27(3):148-57 PubMed

Folia Microbiol (Praha). 2018 Jul;63(4):413-432 PubMed

PLoS One. 2012;7(8):e42539 PubMed

Phys Med. 2012 Jul;28(3):230-9 PubMed

Am J Dent. 2017 Feb;30(1):52-56 PubMed

FEMS Immunol Med Microbiol. 2012 Jul;65(2):381-4 PubMed

Front Microbiol. 2018 May 07;9:898 PubMed

Clin Plasma Med. 2014 Jul;2(1):4-10 PubMed

Biotechnol Adv. 2008 Nov-Dec;26(6):610-7 PubMed

Int J Pharm. 2001 Sep 11;226(1-2):1-21 PubMed

ACS Appl Mater Interfaces. 2017 Dec 20;9(50):43470-43477 PubMed

Int J Food Microbiol. 2015 Oct 1;210:53-61 PubMed

Nat Rev Microbiol. 2017 Dec;15(12):740-755 PubMed

Curr Opin Microbiol. 2004 Dec;7(6):655-60 PubMed

Water Res. 2013 Mar 1;47(3):1381-9 PubMed

Biointerphases. 2015 Jun 16;10(2):029402 PubMed

Apoptosis. 2010 Mar;15(3):257-68 PubMed

Sci Rep. 2016 May 31;6:26320 PubMed

Curr Genet. 2002 Jul;41(4):208-16 PubMed

PLoS One. 2014 Oct 10;9(10):e108512 PubMed

PLoS One. 2016 May 25;11(5):e0155427 PubMed

Sci Rep. 2016 Apr 01;6:23737 PubMed

Biointerphases. 2015 Dec 22;10(4):040801 PubMed

J Endod. 2015 Aug;41(8):1325-30 PubMed

Lett Appl Microbiol. 2007 Sep;45(3):318-23 PubMed

Am J Infect Control. 2005 Mar;33(2):78-82 PubMed

Non-thermal plasma causes Pseudomonas aeruginosa biofilm release to planktonic form and inhibits production of Las-B elastase, protease and pyocyanin

Decontamination of High-Efficiency Mask Filters From Respiratory Pathogens Including SARS-CoV-2 by Non-thermal Plasma

A Review of Microbial Decontamination of Cereals by Non-Thermal Plasma

Non-thermal Plasma Treatment of ESKAPE Pathogens: A Review

Inactivation of Acanthamoeba Cysts in Suspension and on Contaminated Contact Lenses Using Non-Thermal Plasma

Inactivation of Dermatophytes Causing Onychomycosis Using Non-Thermal Plasma as a Prerequisite for Therapy

Multi-Hollow Surface Dielectric Barrier Discharge for Bacterial Biofilm Decontamination

Inactivation of Schistosoma Using Low-Temperature Plasma

Inactivation of Dermatophytes Causing Onychomycosis and Its Therapy Using Non-Thermal Plasma

Combination of non-thermal plasma and subsequent antibiotic treatment for biofilm re-development prevention