Novelty and Convergence in Adaptation to Whole Genome Duplication
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
Grantová podpora
BB/P013511/1
Biotechnology and Biological Sciences Research Council - United Kingdom
PubMed
33783509
PubMed Central
PMC8382928
DOI
10.1093/molbev/msab096
PII: 6203814
Knihovny.cz E-zdroje
- Klíčová slova
- adaptation, convergence, genome duplication, polyploidy,
- MeSH
- Arabidopsis * genetika MeSH
- duplikace genu * MeSH
- genom rostlinný MeSH
- meióza genetika MeSH
- polyploidie MeSH
- segregace chromozomů MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Whole genome duplication (WGD) can promote adaptation but is disruptive to conserved processes, especially meiosis. Studies in Arabidopsis arenosa revealed a coordinated evolutionary response to WGD involving interacting proteins controlling meiotic crossovers, which are minimized in an autotetraploid (within-species polyploid) to avoid missegregation. Here, we test whether this surprising flexibility of a conserved essential process, meiosis, is recapitulated in an independent WGD system, Cardamine amara, 17 My diverged from A. arenosa. We assess meiotic stability and perform population-based scans for positive selection, contrasting the genomic response to WGD in C. amara with that of A. arenosa. We found in C. amara the strongest selection signals at genes with predicted functions thought important to adaptation to WGD: meiosis, chromosome remodeling, cell cycle, and ion transport. However, genomic responses to WGD in the two species differ: minimal ortholog-level convergence emerged, with none of the meiosis genes found in A. arenosa exhibiting strong signal in C. amara. This is consistent with our observations of lower meiotic stability and occasional clonal spreading in diploid C. amara, suggesting that nascent C. amara autotetraploid lineages were preadapted by their diploid lifestyle to survive while enduring reduced meiotic fidelity. However, in contrast to a lack of ortholog convergence, we see process-level and network convergence in DNA management, chromosome organization, stress signaling, and ion homeostasis processes. This gives the first insight into the salient adaptations required to meet the challenges of a WGD state and shows that autopolyploids can utilize multiple evolutionary trajectories to adapt to WGD.
Department of Botany Faculty of Science Charles University Prague Czech Republic
Future Food Beacon of Excellence University of Nottingham Nottingham United Kingdom
Institute of Botany The Czech Academy of Sciences Průhonice Czech Republic
Natural History Museum University of Oslo Oslo Norway
School of Biosciences University of Nottingham Nottingham United Kingdom
School of Life Sciences University of Nottingham Nottingham United Kingdom
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