Activated Protein C Resistance [rezistence k aktivovanému proteinu C]

topical
105
Terms

APC rezistence
faktor V - leidenská mutace
FVL - faktor V Leiden

 

APC Resistance

Persistent link   https://www.medvik.cz/link/D020016
Definition

A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.

DUI
D020016 MeSH Browser
CUI
M0029723
Previous indexing
Factor V/genetics (1994-1998); Protein C (1993-1998)
History note
1999
Public note
1999

Allowable subheadings

BL
blood 5
CF
cerebrospinal fluid 0
CI
chemically induced 0
CL
classification 0
CO
complications 30
CN
congenital 0
DI
diagnosis 33
DG
diagnostic imaging 0
DH
diet therapy 0
DT
drug therapy 4
EC
economics 0
EM
embryology 0
EN
enzymology 0
EP
epidemiology 11
EH
ethnology 0
ET
etiology 4
GE
genetics 39
HI
history 0
IM
immunology 1
ME
metabolism 1
MI
microbiology 0
MO
mortality 2
NU
nursing 0
PS
parasitology 0
PA
pathology 3
PP
physiopathology 3
PC
prevention & control 2
PX
psychology 0
RT
radiotherapy 0
RH
rehabilitation 0
SU
surgery 0
TH
therapy 6
UR
urine 0
VE
veterinary 0
VI
virology 0

C Diseases
C15 Hemic and Lymphatic Diseases 91
C15.378 Hematologic Diseases 973
C15.378.100 Blood Coagulation Disorders 599
C15.378.100.100 Blood Coagulation Disorders, Inherited 61
C15.378.100.100.037 Activated Protein C Resistance 105
C15.378.100.100.056 Afibrinogenemia 39
C15.378.100.100.075 Antithrombin III Deficiency 24
C15.378.100.100.080 Bernard-Soulier Syndrome 9
C15.378.100.100.300 Factor V Deficiency 7
C15.378.100.100.310 Factor VII Deficiency 6
C15.378.100.100.320 Factor X Deficiency 2
C15.378.100.100.325 Factor XI Deficiency 12
C15.378.100.100.330 Factor XII Deficiency 8
C15.378.100.100.335 Factor XIII Deficiency 4
C15.378.100.100.500 Hemophilia A 688
C15.378.100.100.510 Hemophilia B 214
C15.378.100.100.515 Hermanski-Pudlak Syndrome 7
C15.378.100.100.550 Hypoprothrombinemias 4
C15.378.100.100.690 Protein C Deficiency 31
C15.378.100.100.820 Thrombasthenia 7
C15.378.100.100.900 von Willebrand Diseases 103
C15.378.100.100.970 Wiskott-Aldrich Syndrome 20
C15.378.100.141 Coagulation Protein Disorders 52
C15.378.100.141.036 Activated Protein C Resistance 105
C15.378.100.141.072 Afibrinogenemia 39
C15.378.100.141.300 Factor V Deficiency 7
C15.378.100.141.310 Factor VII Deficiency 6
C15.378.100.141.320 Factor X Deficiency 2
C15.378.100.141.325 Factor XI Deficiency 12
C15.378.100.141.330 Factor XII Deficiency 8
C15.378.100.141.335 Factor XIII Deficiency 4
C15.378.100.141.500 Hemophilia A 688
C15.378.100.141.510 Hemophilia B 214
C15.378.100.141.550 Hypoprothrombinemias 4
C15.378.100.141.900 von Willebrand Diseases 103
C15.378.925 Thrombophilia 424
C15.378.925.050 Activated Protein C Resistance 105
C15.378.925.075 Antithrombin III Deficiency 24
C15.378.925.220 Disseminated Intravascular Coagulation 209
C15.378.925.795 Protein C Deficiency 31
C15.378.925.800 Protein S Deficiency 18
C15.378.925.850 Purpura, Thrombotic Thrombocytopenic 94
C16 Congenital, Hereditary, and Neonatal Diseases and Abnormalities 439
C16.320 Genetic Diseases, Inborn 1 213
C16.320.099 Blood Coagulation Disorders, Inherited 61
C16.320.099.037 Activated Protein C Resistance 105
C16.320.099.056 Afibrinogenemia 39
C16.320.099.075 Antithrombin III Deficiency 24
C16.320.099.080 Bernard-Soulier Syndrome 9
C16.320.099.300 Factor V Deficiency 7
C16.320.099.310 Factor VII Deficiency 6
C16.320.099.320 Factor X Deficiency 2
C16.320.099.325 Factor XI Deficiency 12
C16.320.099.330 Factor XII Deficiency 8
C16.320.099.335 Factor XIII Deficiency 4
C16.320.099.417 Gray Platelet Syndrome 1
C16.320.099.500 Hemophilia A 688
C16.320.099.510 Hemophilia B 214
C16.320.099.515 Hermanski-Pudlak Syndrome 7
C16.320.099.550 Hypoprothrombinemias 4
C16.320.099.690 Protein C Deficiency 31
C16.320.099.820 Thrombasthenia 7
C16.320.099.920 von Willebrand Diseases 103
C16.320.099.970 Wiskott-Aldrich Syndrome 20

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