nemoc z nedostatku karbamoylfosfátsyntetázy [Carbamoyl-Phosphate Synthase I Deficiency Disease]

tematický
1
Termíny

deficit karbamoylfosfátsynthasy I
deficit karbamylfosfátsynthetasy I
hyperamonémie z nedostatku karbamoylfosfátsyntetázy I
hyperamonémie z nedostatku karbamoylfosfátsynthasy I
nedostatek karbamoylfosfátsynthasy I
nedostatek karbamylfosfátsynthetasy I
nemoc v důsledku nedostatku karbamoylfosfátsynthasy I

 

Carbamoyl Phosphate Synthase (Ammonia) Deficiency Disease
Carbamoyl Phosphate Synthase 1 Deficiency
Carbamoyl Phosphate Synthetase I Deficiency
Carbamoyl Phosphate Synthetase I Deficiency, Hyperammonemia Due To
Carbamoyl-Phosphate Synthase 1 Deficiency Disease
Carbamoyl-Phosphate Synthase 1 Deficiency Disease (Ornithine Carbamoyl Phosphate Deficiency)
Carbamoyl-Phosphate Synthase I Deficiency Disease (Ornithine Carbamoyl Phosphate Deficiency)
Carbamoyl-Phosphate Synthetase I Deficiency Disease
Carbamoylphosphate Synthetase 1 Deficiency Disease -
Carbamoylphosphate Synthetase I Deficiency Disease
Carbamyl Phosphate Synthetase (CPS) Deficiency
Carbamyl Phosphate Synthetase Deficiency Disease
Carbamyl-Phosphate Synthetase 1 Deficiency Disease
Carbamyl-Phosphate Synthetase I Deficiency Disease
CPS 1 Deficiency
CPS I Deficiency
Hyperammonemia Due to Carbamoyl Phosphate Synthetase 1 Deficiency

Perzistentní odkaz   https://www.medvik.cz/link/D020165
Definice

Vrozená porucha metabolismu močovinového cyklu s autozomálně recesivní dědičností (genový defekt 2p24.3-q31). V popředí je těžká hyperamonemie, zvýšen je také glutamin, hladina močoviny v krvi je snížená. Je nutná redukce bílkovin v potravě. (cit. Velký lékařský slovník online, 2015 http://lekarske.slovniky.cz/ )

A urea cycle disorder manifesting in infancy as lethargy, emesis, seizures, alterations of muscle tone, abnormal eye movements, and an elevation of serum ammonia. The disorder is caused by a reduction in the activity of hepatic mitochondrial CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA). (Menkes, Textbook of Child Neurology, 5th ed, pp50-1)

Anotace
consider also CARBAMOYL-PHOSPHATE SYNTHASE (AMMONIA)/defic
DUI
D020165 MeSH Prohlížeč
CUI
M0328185
Předchozí užití
Amino Acid Metabolism, Inborn Errors (1975-1999); Carbamoyl-Phosphate Synthase (Ammonia)/deficiency (1989-1999); Metabolism, Inborn Errors (1970-1974)
Historická pozn.
2000
Veřejná pozn.
2000

C Nemoci
C10.228.140 nemoci mozku 1 177
C10.228.140.163 metabolické nemoci mozku 84
C10.228.140.163.100.937 vrozené poruchy cyklu močoviny 7
C10.228.140.163.100.937.124 argininjantarová acidurie 2
C10.228.140.163.100.937.374 citrulinemie 2
C10.228.140.163.100.937.500 hyperargininemie 2
C16.320.565.100.940.124 argininjantarová acidurie 2
C16.320.565.100.940.374 citrulinemie 2
C16.320.565.100.940.500 hyperargininemie 2
C16.320.565.189.937.124 argininjantarová acidurie 2
C16.320.565.189.937.374 citrulinemie 2
C16.320.565.189.937.500 hyperargininemie 2
C18.452 metabolické nemoci 1 196
C18.452.132.100.937.124 argininjantarová acidurie 2
C18.452.132.100.937.374 citrulinemie 2
C18.452.132.100.937.437 hyperargininemie 2
C18.452.648.100.940.124 argininjantarová acidurie 2
C18.452.648.100.940.374 citrulinemie 2
C18.452.648.100.940.437 hyperargininemie 2
C18.452.648.189.937.124 argininjantarová acidurie 2
C18.452.648.189.937.374 citrulinemie 2
C18.452.648.189.937.437 hyperargininemie 2
C18.452.660.300 Friedreichova ataxie 54
C18.452.660.520 Leighova nemoc 26
C18.452.660.560 mitochondriální myopatie 40