OBJECTIVES: The aim of this study was to compare short- and longer-term outcomes of David (DV) versus Florida sleeve (FS) procedure in patients requiring valve-sparing aortic root replacement. METHODS: Between January 1996 and December 2020 285 patients received a DV procedure (median age 60 years; 26% females) and 57 patients underwent an FS procedure (median age 64 years; 19% females) in our department. Propensity score matching using patient characteristics led to 58 (DV) versus 57 (FS) patients. End points were defined as primary: freedom from aortic valve and/or aortic root-related reoperation and freedom from aortic regurgitation ≥moderate and secondary: early and late survival. RESULTS: Thirty-day mortality was 2% (DV) and 0% (FS) (P = 0.319). There was 1 early stroke in each group (P = 0.990). Follow-up was complete in 99% with only 1 patient (FS) lost. The 5- and 10-year freedom from aortic valve and/or aortic root related reoperation was 98 ± 2% and 96 ± 3% in the DV group and 92 ± 5% and 84 ± 9% in the FS group, respectively (P = 0.095). The 5- and 10-year freedom from aortic regurgitation ≥moderate was 88 ± 5% and 80 ± 8% in the DV group and 92 ± 5% and 78 ± 1% in the FS group, respectively (P = 0.782). The 5- and 10-year survival rates were 93 ± 4% and 82 ± 6% (DV) vs 75 ± 7% and 67 ± 10% (FS), respectively (P = 0.058). No case of endocarditis (DV) and 3 cases of endocarditis (FS) (P = 0.055) were observed during follow-up. CONCLUSIONS: Both DV and FS resulted in similar early and longer-term outcomes with a trend to slightly better performance and survival in the DV group. Florida sleeve procedure might be an alternative approach for patients with higher-risk profiles requiring valve-sparing aortic root replacement.
- MeSH
- aortální chlopeň chirurgie MeSH
- aortální insuficience * chirurgie MeSH
- endokarditida * chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- reoperace MeSH
- retrospektivní studie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- mitrální chlopeň MeSH
- srdeční chlopně umělé * MeSH
- trikuspidální chlopeň MeSH
- Publikační typ
- dopisy MeSH
- komentáře MeSH
BACKGROUND: The aim of this study was to assess effectiveness, stability, position, and expansibility of an expansible aortic annuloplasty ring with computed tomography (CT). METHODS: Ten men (median age 51 years) scheduled for aortic root remodeling with implantation of external annuloplasty ring underwent contrast-enhanced CT of the aortic root preoperatively, postoperatively, and at a median of 21 months after operation. A reconstructed transverse double oblique view of the aortic base (AB) and of the new defined annuloplasty ring base (ARB; plane of the lower edge of the ring) in systole and diastole were obtained. The diameters, perimeter, and area were measured. In addition, the distances between AB and ARB in the nadir of each sinus were measured. RESULTS: We found 12% reduction of the postoperative AB and 19% of ARB perimeter in both systole (p = 0.004, p < 0.001, respectively) and diastole (p = 0.001, p < 0.001, respectively) compared with preoperative. There was 22% reduction of the postoperative AB area in systole and 24% in diastole (p = 0.002, p = 0.001, respectively) and 33% reduction of the ARB area in systole and 32% in diastole (p < 0.001 for both) compared with the preoperative period. Nearly all measured variables in the follow-up period showed a slight increase compared with the postoperative period; however, they did not reach statistical significance. The postoperative systolic-diastolic differences in the three measured variables at the level of AB and ARB were statistically significant and were maintained throughout the follow-up period. The base of the ring was implanted 2 ± 2 mm at the right, 0 ± 1 mm at the left above the AB, and 2 (-3 to 2) mm at the noncoronary nadir below the AB. CONCLUSIONS: This study demonstrates imaging evidence of the effectiveness, stability, and pulsatility of the annuloplasty ring in aortic root remodeling in follow-up and describes the exact position of the ring at the base of the aortic root.
- MeSH
- anuloplastika srdeční chlopně metody MeSH
- aorta thoracica diagnostické zobrazování patofyziologie MeSH
- aortální chlopeň diagnostické zobrazování chirurgie MeSH
- aortální insuficience diagnóza patofyziologie chirurgie MeSH
- časové faktory MeSH
- dospělí MeSH
- funkce levé komory srdeční fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- počítačová rentgenová tomografie metody MeSH
- protézy - design MeSH
- protézy a implantáty * MeSH
- retrospektivní studie MeSH
- senioři MeSH
- zobrazování trojrozměrné * MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: The aim of this study was to analyze short- and mid-term results after aortic valve (AV) repair with particular regard to the impact of valve cuspidity (bicuspid versus tricuspid aortic valve). METHODS: One hundred patients with aortic regurgitation (AR) undergoing aortic valve repair between November 2007 and October 2012 were included in the study. Sixty patients had bicuspid AV (BAV group; 11 females) and 40 patients had tricuspid AV (TAV group; 13 females). AR > grade 2 was present in 47 (78%) patients in the BAV and in 35 (88%) patients in the TAV group. Follow-up was complete in 100% and median was 25 months. RESULTS: Isolated aortic valve repair was performed in 27 (45%) of BAV patients and in six (15%) of TAV patients. Replacement of the ascending aorta and/or aortic root was performed in 33 (55%) of BAV patients and in 34 (86%) of TAV patients. There was no death within 30 days postoperatively, while two patients died (TAV group) during the follow-up period. There was no statistical difference between BAV and TAV groups with regard to the survival (100 ± 0% vs. 95 ± 4%, p = 0.102), the three-year freedom from AV-related reoperation (90 ± 5% vs. 89 ± 6%, p = 0.456), and the three-year freedom from AR grade > 2 (86 ± 6% vs. 82 ± 7%, p = 0.866), respectively. CONCLUSIONS: This study demonstrates no difference in mid-term results after regurgitant bicuspid and tricuspid aortic valve repair, suggesting that bicuspid valve may not be a risk factor for aortic valve repair.
- MeSH
- aortální chlopeň abnormality MeSH
- aortální insuficience chirurgie MeSH
- časové faktory MeSH
- dospělí MeSH
- kardiovaskulární chirurgické výkony MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- následné studie MeSH
- nemoci srdečních chlopní MeSH
- recidiva MeSH
- reoperace statistika a číselné údaje MeSH
- retrospektivní studie MeSH
- rizikové faktory MeSH
- senioři MeSH
- trikuspidální chlopeň MeSH
- věkové faktory MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
A hybrid approach to elephant trunk technique for treatment of thoracic aortic aneurysms combines a conventional surgical and endovascular therapy. Compared to surgery alone, there is a presumption that mortality and morbidity is reduced. We present a case report of a 42-year-old man with a giant aneurysm of the entire thoracic aorta, significant aortic and tricuspid regurgitation and ventricular septum defect. The patient underwent multiple consecutive operations and interventions having, among others, finally replaced the entire thoracic aorta with the use of the hybrid elephant trunk technique.
- MeSH
- aneurysma hrudní aorty komplikace diagnóza chirurgie MeSH
- cévy - implantace protéz metody MeSH
- dospělí MeSH
- endovaskulární výkony metody MeSH
- lidé MeSH
- stenty * MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- práce podpořená grantem MeSH
Úvod: Cílem práce je zhodnocení krátkodobých a střednědobých výsledků plastik aortální chlopně. Metodika: V období od listopadu 2007 do října 2012 bylo na Kardiochirurgické klinice FN Hradec Králové operováno celkem 100 pacientů s aortální regurgitací, u kterých byla provedena plastika aortální chlopně (24 žen; průměrný věk 50,3 roku; rozmezí 23–77 let). Šedesát pacientů mělo bikuspidální aortální chlopeň a 82 pacientů mělo aortální regurgitaci (AR) > 2. Vzestupná aorta/kořen aorty byly nahrazeny u 67 pacientů. Plastika cípů aortální chlopně byla provedena u 74 pacientů a u 48 nemocných bylo nutné stabilizovat aortální anulus. Délka sledování se pohybovala od 1 do 59 měsíců (kumulativní hodnota 220 paciento-roků; medián 25 měsíců). Sledování bylo kompletní ve 100 % případů. Výsledky: Třicetidenní mortalita byla 0% a během následného sledování zemřeli dva pacienti (přežívání je 98%). Z důvodu progrese AR bylo nutné u osmi pacientů provést reoperaci a u dalších šesti pacientů byla zjištěna AR > 2. Během sledování se nevyskytl žádný případ krvácivé nebo tromboembolické příhody. Rovněž všechny reoperace proběhly bez komplikací. Závěry: Analýza krátkodobých a střednědobých dat prokázala vynikající přežívání operovaných pacientů a uspokojivé výsledky plastik aortální chlopně, srovnatelné s výsledky ostatních publikovaných studií. Domníváme se proto, že tyto operace
Introduction: The aim of this study was to analyze short- and mid-term results of aortic valve repair. Material and methods: One hundred consecutive patients (24 females; mean age 50.3 years, range 23–77 years) with aortic regurgitation underwent aortic valve repair between November 2007 and October 2012. Sixty patients had bicuspid aortic valve, and 82 patients demonstrated aortic regurgitation greater than mild (> grade 2). The ascending aorta/aortic root was replaced in 67 patients. Aortic cusp repair was necessary in 74 patients and additional aortic annulus stabilization was required in 48 cases. Follow-up ranged from 1 to 59 months (cumulative of 220 patient-years, median 25 months) and was complete in 100%. Results: There was no 30-day mortality and 2 patients died in the follow-up. The overall 4-year survival was 98% and freedom from cardiac death was 99% at 4 years. During the follow-up 8 patients underwent aortic valve-related reoperation due to progression of aortic regurgitation and another 6 patients showed aortic regurgitation. In both aspects there was no statistically significant difference between patients without and with aortic root replacement (p = .402 and p = .650). There were no significant bleeding or thromboembolic events during the follow-up. Conclusions: Short- and mid-term data analysis revealed an excellent survival and acceptable results of aortic repair, comparable with other larger published studies. We think, therefore, aortic valve repair should be a part of contemporary cardio-surgical armamentarium, especially in younger patients with an appropriate indication.
- MeSH
- analýza přežití * MeSH
- aortální insuficience * diagnóza epidemiologie chirurgie klasifikace MeSH
- chirurgická náhrada chlopně * metody statistika a číselné údaje MeSH
- lidé středního věku MeSH
- lidé MeSH
- pooperační komplikace etiologie mortalita MeSH
- reoperace statistika a číselné údaje MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- práce podpořená grantem MeSH
BACKGROUND AND AIM: Isolated thoracic aortitis (ITA) is a newly-defined pathological entity with a still-unknown etiopathology and with some potential relationship to IgG4-related systemic disease. We investigated patients on whom the ascending aorta was operated to identify the clinical and histopathological features of ITA and its relationship to IgG4-related systemic disease. METHODS: Two hundred fifty-one patients underwent replacement of the ascending aorta. Retrospective review of all histological reports was done to identify noninfectious aortitis. Immunohistochemical analysis of resected specimens was performed in all cases. RESULTS: We found 11 (4.4%) patients with noninfectious aortitis aged 52 to 79 years; nine of the patients were female. All patients underwent ascending aorta replacement. The 30-day mortality was 0. During the follow-up period (median 12 months) four patients died (two of them because of progression of aortic disease). None of the seven living patients developed any IgG4-related diseases, and all had normal serum levels of IgG and IgG4. CONCLUSIONS: Surgical treatment of ITA has acceptable short- and mid-term results. Because follow-up serum levels of IgG and IgG4 were normal in survivors, postoperative corticosteroid therapy may not be indicated in patients in the absence of active vasculitis.
- MeSH
- aneurysma hrudní aorty etiologie chirurgie MeSH
- aorta thoracica chirurgie MeSH
- aortitida komplikace diagnóza epidemiologie imunologie MeSH
- biologické markery krev MeSH
- cévy - implantace protéz MeSH
- disekce aorty etiologie chirurgie MeSH
- imunoglobulin G krev MeSH
- incidence MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- retrospektivní studie MeSH
- senioři MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- hodnotící studie MeSH
- práce podpořená grantem MeSH