- MeSH
- bradykardie diagnostické zobrazování MeSH
- echokardiografie MeSH
- elektrokardiografie metody MeSH
- kardiovaskulární nemoci diagnostické zobrazování etiologie patologie MeSH
- lidé MeSH
- mentální anorexie komplikace MeSH
- perikardiální tekutina diagnostické zobrazování MeSH
- rizikové faktory MeSH
- srdeční frekvence MeSH
- Check Tag
- lidé MeSH
- MeSH
- adherence pacienta MeSH
- diabetes mellitus 2. typu * epidemiologie metabolismus MeSH
- diabetické angiopatie epidemiologie metabolismus prevence a kontrola MeSH
- dieta aterogenní * MeSH
- dospělí MeSH
- kardiovaskulární nemoci * prevence a kontrola MeSH
- lidé MeSH
- průzkumy a dotazníky MeSH
- randomizované kontrolované studie jako téma MeSH
- rizikové faktory MeSH
- triglyceridy krev MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- komentáře MeSH
- souhrny MeSH
OBJECTIVE: To evaluate the association of heart rate variability (HRV) examined in supine and standing position with ambulatory blood pressure monitoring (ABPM) in patients with anorexia nervosa (AN). METHODS: HRV in supine and standing position and ABPM were examined in 30 AN patients and 30 control subjects. The correlations between HRV and ABPM were evaluated. RESULTS: The average age was 25±5 in AN patients and 25±4 years in controls (NS). LF (low frequency) power in AN patients and controls was comparable in supine position. LF power significantly increased during standing in controls, but no increment was detected in AN patients. The HF (high frequency) power was significantly increased in AN patients in supine position, but after standing was comparable with controls. The ratio LF/HF was lower both in supine and standing position in AN patients but the differences did not reach statistical significance. Blood pressure values in AN patients were comparable with controls in supine position but were significantly lower in standing position. Ambulatory blood pressure values were significantly lower in AN patients during active but not sleeping period. In standing position HF and LF powers positively and LF/HF negatively correlated with ABPM blood pressure values during active period in controls while in AN patients only LF power correlated with diastolic and mean blood pressures. CONCLUSION: The lower ABPM values in AN patients during active period in comparison with control subjects may be explained by HRV changes, mainly by its impaired relations with blood pressure in standing position.
- MeSH
- ambulantní monitorování krevního tlaku metody psychologie statistika a číselné údaje MeSH
- bdění fyziologie MeSH
- dospělí MeSH
- lidé MeSH
- mentální anorexie patofyziologie MeSH
- postura těla fyziologie MeSH
- spánek fyziologie MeSH
- srdeční frekvence fyziologie MeSH
- studie případů a kontrol MeSH
- supinační poloha fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- MeSH
- bradykardie diagnóza klasifikace MeSH
- bulimia etiologie mortalita patofyziologie MeSH
- dospělí MeSH
- elektrokardiografie klasifikace MeSH
- hypotenze diagnóza klasifikace MeSH
- index tělesné hmotnosti MeSH
- kardiovaskulární nemoci * etiologie patofyziologie MeSH
- lidé MeSH
- mentální anorexie etiologie mortalita patofyziologie MeSH
- mladý dospělý MeSH
- nemoci autonomního nervového systému farmakoterapie patofyziologie terapie MeSH
- poruchy příjmu potravy * patofyziologie MeSH
- prognóza MeSH
- zátěžová echokardiografie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladý dospělý MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
ECG body surface mapping (BSM) parameters in patients with diabetes mellitus Type 1 (DM1) are significantly different comparing to healthy non-diabetic subjects. Hypothesis that these changes are more pronounced in DM1 patients with autonomic neuropathy (AN) was tested. The parameters of BSM were registered by diagnostic system Cardiag 112.2 in 54 DM1 patients including 25 with AN and 30 control subjects. AN was diagnosed according to Ewing criteria when two or more Ewing tests were abnormal. In classic 12-lead ECG the heart rate was increased, QRS and QT shortened (p<0.01) and QTC prolonged in DM1 patients. The VCG measurement of QRS-STT angles and spatial QRS-STT angle showed non-significant differences. The absolute values of maximum and minimum in depolarization and repolarization isopotential, isointegral, isoarea maps were significantly different in DM1 patients in comparison with controls (p<0.01). The changes were more pronounced in DM1 patients with AN than in DM patients without AN (p<0.05). The QT duration measured in 82 leads of thorax was significantly shortened in 68 leads of both groups of DM 1 patients (p<0.01) when compared with controls. In 34 of them this shortening was more pronounced in DM1 patients with AN than in DM1 patients without AN (p<0.05). The results showed that the method of ECG BSM is capable to confirm the presence of autonomic neuropathy in diabetic patients.
- MeSH
- diabetes mellitus 1. typu patofyziologie MeSH
- diabetické neuropatie diagnóza patofyziologie MeSH
- dospělí MeSH
- elektrokardiografie metody MeSH
- financování organizované MeSH
- klinické zkoušky kontrolované jako téma MeSH
- lidé MeSH
- mapování potenciálů tělesného povrchu metody MeSH
- nemoci autonomního nervového systému dietoterapie patofyziologie MeSH
- srdeční frekvence fyziologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- srovnávací studie MeSH
This study compared the effects of soybean oil- versus olive oil-based lipid emulsions on hepatobiliary function and serum triacylglycerols in patients who required transient parenteral nutrition support for significant weight loss. Patients who received a parenteral ready-to-use industry admixture including either soybean oil- (n = 10) or olive oil-based lipid emulsion (n = 11) for 2 weeks were retrospectively analysed. Cholestatic and cytolytic enzymes, conjugated bilirubin and serum triacylglycerols were sampled before and 1 day after completing parenteral nutrition support. Significant deterioration of cholestatic enzymes occurred in five patients in the soybean oil group and in one in the olive oil group. Serum triacylglycerols significantly deteriorated in seven patients in the soybean oil group and in one patient in the olive oil group. No differences were recorded for cytolytic enzyme abnormalities. In conclusion, the olive oil-based emulsion induced abnormalities of cholestatic enzymes and serum triacylglycerols significantly less frequently than the soybean oil-based emulsion.
- MeSH
- hmotnostní úbytek účinky léků MeSH
- jaterní testy MeSH
- játra fyziologie účinky léků MeSH
- lidé středního věku MeSH
- lidé MeSH
- oleje rostlin aplikace a dávkování MeSH
- parenterální výživa MeSH
- sójový olej aplikace a dávkování MeSH
- stravovací zvyklosti účinky léků MeSH
- triglyceridy krev MeSH
- tukové emulze intravenózní aplikace a dávkování farmakologie MeSH
- žlučové ústrojí fyziologie účinky léků MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- srovnávací studie MeSH
We evaluated and measured by high performance liquid chromatography the plasma amino acid levels in 11 female patients with anorexia nervosa during a period of significant loss of body weight, compared with 11 healthy age-matched controls. Total amino acid and total branched-chain amino acid levels were similar in both groups, however significantly higher levels of glycine and ornithine were found in anorexia nervosa patients, as well as significantly lower levels of leucine, tyrosine and lysine compared with controls. The glycine/valine and phenylalanine/tyrosine ratios were significantly higher in anorexia nervosa patients than in control subjects. The levels and ratios of other amino acids were within the normal range, with no significant differences between the two groups. Changes in the plasma amino acid profile in anorexia nervosa patients can be explained by chronic severe malnutrition and prolonged stress.
