BACKGROUND: The Roma population is a genetically isolated population with a shared origin, totaling between 10 to 14 million individuals worldwide, stemming from a limited number of “genetic founders”. Roma individuals exhibit specific hereditary diseases, often stemming from recessive genetic variants due to a higher degree of consanguinity, with recent molecular-genetic investigations shedding light on several conditions prevalent within the Czech Roma population. However, an overview of stomatological issues in diagnosing such diseases proves challenging, leading to frequent underdiagnosis or misdiagnosis. METHODS: The contribution monitors the clinical description, typical symptoms and treatment options including dental abnormalities in rare genetic diseases in the Roma population which are treated in ERN CRANIO centre at Motol University Hospital in Prague. RESULTS: Our research provides examples of autosomal recessive diseases, which can be molecularly confirmed, and prevalent within the Roma community. These include congenital cataract syndrome, facial dysmorphism and demyelinating neuropathy, non-syndromic prelingual e.g. deafness with GJB2 gene impairment, and myasthenic syndrome. CONCLUSION: Our report aimed to provide a systematic review of dental phenotypes which can relate to Czech Roma’s rare genetic disorders therapy including dental treatment. Understanding is important for preventing unterdiagnosis or treatment for the patients affected review of observed (Fig. 6, Ref. 27).
- MeSH
- abnormality zubů * genetika diagnóza etnologie MeSH
- lidé MeSH
- Romové * genetika MeSH
- syndrom MeSH
- vzácné nemoci genetika MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- systematický přehled MeSH
- Geografické názvy
- Česká republika MeSH
BACKGROUND: The Roma population is a genetically isolated population with a shared origin, totaling between 10 to 14 million individuals worldwide, stemming from a limited number of "genetic founders". Roma individuals exhibit specific hereditary diseases, often stemming from recessive genetic variants due to a higher degree of consanguinity, with recent molecular-genetic investigations shedding light on several conditions prevalent within the Czech Roma population. However, an overview of stomatological issues in diagnosing such diseases proves challenging, leading to frequent underdiagnosis or misdiagnosis. METHODS: The contribution monitors the clinical description, typical symptoms and treatment options including dental abnormalities in rare genetic diseases in the Roma population which are treated in ERN CRANIO centre at Motol University Hospital in Prague. RESULTS: Our research provides examples of autosomal recessive diseases, which can be molecularly confirmed, and prevalent within the Roma community. These include congenital cataract syndrome, facial dysmorphism and demyelinating neuropathy, non-syndromic prelingual e.g. deafness with GJB2 gene impairment, and myasthenic syndrome. CONCLUSION: Our report aimed to provide a systematic review of dental phenotypes which can relate to Czech Roma's rare genetic disorders therapy including dental treatment. Understanding is important for preventing unterdiagnosis or treatment for the patients affected review of observed (Fig. 6, Ref. 27).
- MeSH
- abnormality zubů * genetika diagnóza etnologie MeSH
- lidé MeSH
- Romové * genetika MeSH
- syndrom MeSH
- vzácné nemoci genetika MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- systematický přehled MeSH
- Geografické názvy
- Česká republika MeSH
The goal of study was to explore the role of 3D CBCT (cone beam computer tomography) in detecting impacted canines and their movement to evaluate the influence of orthodontic therapy parameters on treatment options, and to monitor quality of healing process based on shape and size of sinus maxillae volume. It is known that the volume of maxillary sinus plays an important role in patients with impacted teeth. The prospective study consisted of 26 individuals. For each individual, pre-treatment and post-treatment CBCT data were acquired. Changes of size, and position of impacted canine in 3D CBCT image before and after therapy were prepared using 3D reconstruction. Volumetric measurements of the maxillary sinuses were performed before and after orthodontic therapy of impacted canines, using InVivo6 software. The main effects MANOVA performed on linear measurements showed metric differences between pre-op and post-op images. A paired t-test showed no statistically significant differences between pre-op and post-op values of the sinus volume. Changes of size and position of impacted canine in 3D image before and after therapy were precise and reproducible, using 3D reconstruction in three planes - horizontal, midsagittal, and coronal. The linear measurements showed metric differences between pre-op and post-op images.
- MeSH
- lidé MeSH
- počítačová tomografie s kuželovým svazkem metody MeSH
- prospektivní studie MeSH
- sinus maxillaris diagnostické zobrazování MeSH
- špičák diagnostické zobrazování MeSH
- zaklíněný zub * diagnostické zobrazování terapie MeSH
- zobrazování trojrozměrné metody MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Generally, the Roma population has problems with treatment options and often experiences discrimination due to structural barriers when accessing health services and for that reason may mistrust those services. The aim of our study is to evaluate the most efficient systems for the engagement of the Roma community aimed at enhancing trust in health services, mainly in the field of dentistry. Since the overall state of dentition significantly affects the quality of life, it is not possible to neglect dental care in excluded localities. A combined social and healthcare approach that represents the basic pillars of prevention (comprising dental hygiene, diet, application of fluoride preparations, and possibly remineralization of the enamel) should create specialized teams including dentists, general practitioners for children and adults, including parents of patients. As we show in specific examples, clear and simple education could markedly improve this situation. The main outputs of our study are recommendations for practice which form the basis for future dental therapy approaches in excluded localities in Czechia.
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- MeSH
- adherence pacienta MeSH
- lidé MeSH
- orální hygiena MeSH
- Romové MeSH
- sociální péče MeSH
- stomatologická péče o děti MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
Objective: Photobiomodulation therapy (PBMT) applies therapeutic lasers or light-emitting diodes radiation to the surface of the body. From the medical point of view, PBMT systems have been employed for reducing pain, inflammation, and edema, promoting healing of wounds, deeper tissues and nerves, preventing tissue damage, etc. Background data: PBMT or biostimulation has a wide range of applications in maxillofacial surgery. It is known that the therapy effect using three-dimensional (3D) image was not really clear during the healing process. Materials and methods: The treatment group comprised 38 patients, 18 of them were treated with laser radiation (diode laser 808 nm) and 20 patients presented the control group. The surgery plan was monitored using cone beam computed tomography, in particular the number, shape, and size of mesiodens were registered. The effectivity of laser therapy was assessed based on immunological tests-secretory immunoglobulin A (sIgA) and lysozyme levels measured in nonstimulated saliva before and after treatment. Results: For sIgA (both in millimeters and milligrams per liter), the measurements displayed differences between pre- and postsurgery values, the postsurgery values being significantly lower than the presurgery values. In addition, interaction with the laser treatment plan was found, meaning that the laser treatment affected the sIgA levels. The decrease in sIgA levels in the control group was statistically significant. However, there was no significant change in sIgA levels in the laser group. The lysozyme trends appeared to be identical to the sIgA levels, that is, rising in the laser group and decreasing in the control group. The initial values for each group, however, go in the opposite direction. Conclusions: The study has shown that the 3D techniques and technologies in combination with therapeutic laser systems could support not only a treatment plan, but they also directly influence the process of healing and reduce inflammation. The study was carried out under clinical project No. 00064203 (FN MOTOL).
Aim: The presented study aim was to find out whether a cephalogram and a scan generated from 3D CBCT of one and the same patient are different or identical. Material and method: The retrospective study included 41 patients with complete orthodontic documentation with a cephalogram and a CBCT taken prior to treatment. The CBCT can be synthesized into cephalogram in orthogonal and perspective projections with Dolphin Imaging 11.95 Premium (Dolphin Imaging and Management Solutions, Chatsworth, CA, USA). Both scans were taken within one month. The same software was used for cephalometric analysis of cephalograms and CBCT generated scans. 7 angular and 3 linear parameters (including dental and skeletal parameters in sagittal and vertical planes) were selected for the study. Results: Statistically significant differences between scans made with three different techniques were found in the following parameters: angular dimension of SNB, and linear parameters WITS, U1-APo, L1-APo. Conclusion: The individual techniques differ to some extent. However, majority of differences in mean values was < 0.6° and < 0.7 mm which suggests that their significance is not important from clinical viewpoint. The techniques are comparable.
Forensic dental identification has employed traditionally 2D digital radiological imaging techniques. More recently, 3D cone beam computer tomography (CBCT) data, widely applied in clinical dentistry, have been gradually used. The purpose of this study was to compare the precision and quality of 2D digital orthopantomogram (OPG) and 2D OPG images generated from cone beam computed tomography (CBCT). The study sample consisted of 50 patients with archived conventional 2D OPG and 3D CBCT images. Patients signed an informed consent form to take part in our study. Measurements of the mandible, teeth and dental restorations were taken by two observers on calibrated 2D OPG and 3D CBCT-to-OPG images using measurement functionalities of DOPLHIN software. Acquired dimensions were compared side by side and images of fillings were superimposed. For better visual comparison and more efficient image registration, the methods of spline interpolation were used. The pairs of absolute measurements obtained from conventional OPG and CBCT-to-OPG-converted images were highly correlated (p < 0.05). However, larger, and horizontally measured distances were revealed to be more affected than shorter vertically taken measurements. In relative terms, CBCT-generated width/length indices of the canines and the first molars ranged from 84% to 99.8% of those acquired from traditional OPGs. In addition, corresponding points on the teeth and fillings were compared side by side and in superimposition. The average coincidence of images was 6.1%. The results revealed that for selected metric variables 2D OPGs and 3D CBCT-generated OPGs were complementary and could be used for forensic comparisons.
- MeSH
- digitální zubní radiografie metody MeSH
- lidé MeSH
- mandibula MeSH
- počítačová tomografie s kuželovým svazkem metody MeSH
- rentgendiagnostika panoramatická metody MeSH
- senzitivita a specificita MeSH
- soudní stomatologie * metody MeSH
- trvalá zubní náhrada MeSH
- zuby MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- MeSH
- lidé MeSH
- mezioborová komunikace MeSH
- oběti zločinu MeSH
- soudní antropologie * MeSH
- soudní stomatologie MeSH
- tělesné pozůstatky MeSH
- zuby * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- rozhovory MeSH
