Úvod: Akútna makulárna neuroretinopatia (AMN) je raritné ochorenie, neistej etiológie, ktoré najčastejšie postihuje mladé ženy. Cieľ: Cieľom práce je popísať kazuistiku pacientky s bilaterálnou AMN pri aktívnej akútnej infekcii COVID-19. Metodika: 32ročná pacientka s 2 dňovou anamnézou zhoršeného videnia bilaterálne prichádza na pohotovosť očnej kliniky Ústrednej vojenskej nemocnice SNP v Ružomberku, Slovensko. Symptomatika infekcie COVID-19 v trvaní 3 dni pred nástupom vizuálnych ťažkostí. Výsledky: Pri primárnom vyšetrení vstupná centrálna zraková ostrosť bilaterálne 20/40 nekoriguje, prítomné paracentrálne skotómy viac vpravo. Pri vyšetrení očného pozadia zneostrené okraje terča zrakového nervu viac vľavo, okolo fovey prítomné hnedočervené petaloidné lézie, periféria bez patologického nálezu. Realizované OCT a OCTA so záverom bilaterálnej AMN pri infekcii COVID-19 s nasadením nízkomolekulárneho heparínu (LMWH) v preventívnej dávke. Záver: V súčasnej dobe pribúda počet zdokumentovaných očných komplikácií infekcie COVID-19 vrátane mikrovaskulárnych príhod.
Aim: The aim of the present paper is to describe the case study of a female patient with bilateral AMN, suffering from active acute infection with COVID-19. Methods: A 32-year-old female patient with impaired vision bilaterally persisting for 2 days reported to the emergency Department of Ophthalmology at the Central Military Hospital in Ružomberok, Slovakia. The patient manifested symptoms of COVID-19 infection persisting for 3 days before the onset of visual complaints. Results: At the primary examination, initial best corrected central visual acuity was 20/40 bilaterally, paracentral scotomas were present more in the right eye. Upon examination of the ocular fundus, the edges of the optic nerve disc were out of focus more in the left eye; brownish red petaloid lesions were present around the fovea, the periphery was without pathological findings. OCT and OCTA were performed, with a conclusion of bilateral AMN upon a background of COVID-19 infection. Low molecular weight heparin (LMWH) was administered in a preventive dose. Conclusion: The number of documented ocular complications of COVID-19 infection, including microvascular events, is currently increasing.
- MeSH
- COVID-19 * diagnóza komplikace MeSH
- dospělí MeSH
- heparin nízkomolekulární farmakologie terapeutické užití MeSH
- lidé MeSH
- syndromy bílých teček * diagnóza etiologie MeSH
- výsledek terapie MeSH
- zrakové testy metody MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- Klíčová slova
- Fracastoro, Girolamo, Jenner, Edward, Semmelweis, Ignaz, Koch, Robert,
- MeSH
- infekce * dějiny MeSH
- lidé MeSH
- nemoci, jimž lze předcházet očkováním dějiny MeSH
- přenos infekční nemoci MeSH
- významné osobnosti MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- historické články MeSH
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
- Publikační typ
- abstrakt z konference MeSH
OBJECTIVES: The aim of this study is to analyse levels of selected heavy metals: chromium (Cr), cadmium (Cd), copper (Cu), manganese (Mn), and lead (Pb), and to recognize factors related to wells' stewardship. METHODS: The pilot study was realized in May 2018 in three villages in northwest of Slovakia. We analysed 69 water samples from private wells. The data on wells and well owners were obtained by self-administered questionnaire. The samples were analysed by atomic absorption spectroscopy with graphite furnace GF AAS (AAS GBC XplorAA 5000 with GBC GF 5000) equipped with hollow cathode lamps. Levels of heavy metals were compared with parametric values for drinking water stated in the Resolution of the Ministry of Health of the Slovak Republic No. 247/2017 Coll. RESULTS: The results indicated spatial variability in some heavy metal levels. Cadmium was not quantified in any sample. Copper and chromium levels were below the parametric value. Parametric values for manganese and lead were exceeded in 19 (27.5%) and 2 (2.9%) samples, respectively. Only 18 owners tested water quality. Busyness and financial cost most frequently discouraged users to carry out the water quality analysis. CONCLUSIONS: The presence of heavy metals in well water can pose a serious public health problem, especially in rural areas without public water supply. Education on heavy metals' risks targeted at well owners could increase the awareness of the issue and minimize possible public health consequences.
- MeSH
- hodnocení rizik MeSH
- kvalita vody MeSH
- lidé MeSH
- monitorování životního prostředí MeSH
- pilotní projekty MeSH
- těžké kovy * analýza MeSH
- zásobování vodou MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Slovenská republika MeSH
INTRODUCTION: Analysis of the occurrence of cadmium and chromium in selected samples of fruit spirits intended for own consumption. MATERIAL AND METHODS: In our pilot study, we analysed 89 samples of fruit spirits intended for own consumption. The samples were mineralized with use of microwave decomposition system MULTIWAVE 60 50 Hz and analysed by atomic absorption spectrometry with a graphite furnace (AAS GBC XPLORAA 5000 with GF 5000). RESULTS: Most of the analysed samples originated from plums (39), apples (38) and pears (5). The average ethanol concentration was 53.7%. Cadmium and chromium were detected in all samples. The highest concentration of chromium and cadmium was found in the apple spirit (31.9 ± 6.6 μg/l and 40.1 ± 8.3 μg/l). CONCLUSIONS: The ethanol concentration in the samples was higher than in distribution spirits. Concentrations of chromium in all samples did not exceed the limit given by the Slovak legislation or the limit of the AMPHORA. The permissible cadmium concentration (10 μg/l according to the AMPHORA) was exceeded in 9 samples. This indicates the potential importance of cadmium compared to chromium. Due to the lack of information in this field, the study presents an important starting point for further research.
OBJECTIVES: The purpose of this study was to identify personal variables and nonoccupational risk factors for carpal tunnel syndrome and to analyse the strength of association of these factors. METHODS: We performed a case-control study with 162 cases and 300 controls. We studied consecutive patients with an electrophysiologically confirmed diagnosis of symptomatic carpal tunnel syndrome. Univariate analysis was performed in the case group and control comparing them for presence of various risk factors. Multivariate analysis was carried out through logistic regression. RESULTS: The mean BMI and age were greater in the case group than in the control. Multivariate analysis showed that BMI (OR = 1.05, 95% CI = 1.01-1.11) and arterial hypertension (OR = 4.63, 95% CI = 2.88-7.44) were the only factors significantly associated with carpal tunnel syndrome. The age, cigarette smoking and alcohol drinking were at the edge of significance. CONCLUSIONS: Carpal tunnel syndrome is the most common peripheral neuropathy and has been related to occupational activities in some but not all studies. Clarifying this relationship has important implications for workers' compensation systems. Based on our findings, BMI and arterial hypertension are considered to be the most significant risk factors of carpal tunnel syndrome in our study.
- MeSH
- lidé MeSH
- logistické modely MeSH
- rizikové faktory MeSH
- studie případů a kontrol MeSH
- syndrom karpálního tunelu * epidemiologie etiologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
