Autoři předkládají kazuistiku mladého muže, u kterého byla diagnostikována cholera po návratu z měsíčního pobytu v Indii. Průběh onemocnění hodnotí jako středně těžký. Původcem onemocnění bylo prokázáno Vibrio cholerae 01, biotyp El Tor, sérovar Ogawa. Jde o první případ diagnostikované importované cholery na našem území od r. 1986.
The authors describe the case of a young man, in whom cholera was diagnosed after his return from a one-month stay in India. They consider that the course of the disease was of medium severity. The pathological agent was safely demonstated: Vibrio cholerae 01, biotype El Tor, serotype Ogawa. This is the first case of imported cholera diagnosed in this country since 1986.
- MeSH
- cholera diagnóza přenos terapie MeSH
- lidé MeSH
- přenos infekční nemoci statistika a číselné údaje MeSH
- Vibrio cholerae klasifikace MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
A new coccidian parasite of the genus Eimeria Schneider, 1875 is described from the subterranean African silvery mole-rat Heliophobius argenteocinereus Peters, 1846. Oocysts of Eimeria burdai sp. n. were subspherical to broadly ellipsoidal 17.8 (16-19) x 14.1 (12-15), with a shape index 1.2 (1.1-1.4). Oocyst wall was bilayered, smooth and colourless, approximately 1.0 thick. Outer layer was significantly thicker than inner one. A micropyle and oocyst residuum were absent. One or two ellipsoidal or spherical polar granules were present. Sporocysts were ellipsoidal, 10.8 (9-12) x 6.2 (5-8) with a shape index 1.7 (1.5-1.9). Sporocyst wall was single-layered, thin, smooth and colourless, with small Stieda body at the pointed end. In freshly sporulated oocysts, spherical sporocyst residuum was composed of small granules enclosed by a thin membrane. Sporozoites were elongate, lying length-wise in the long axis of the sporocyst, partially curled around each other, with single large refractile body located posteriorly. Faintly distinguishable nucleus was in the central part of the sporozoite. This eimerian represents the first coccidian species described from subterranean African silvery mole-rat (Rodentia: Bathyergidae).
- MeSH
- Eimeria klasifikace růst a vývoj izolace a purifikace MeSH
- kokcidióza parazitologie veterinární MeSH
- mikroftalmičtí podzemní hlodavci parazitologie MeSH
- nemoci hlodavců parazitologie MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Afrika MeSH
A macroscopic, microscopic and scanning electron microscope study was performed on the pathological bone changes of the mandibles of wild red deer (n = 61) exhibiting severe dental fluorosis. The animals originated from a highly fluoride polluted area in Central Europe (Ore mountains and their southern foreland, Czech-German border region) and constituted 11.2 % of the studied red deer sample (n = 545) from this area. Pathologically increased wear and fracture of fluorosed teeth caused a variety of mandibular bone alterations, including periodontal breakdown, periostitis, osteitis and chronic osteomyelitis. As a further consequence of severe dental attrition, opening of the pulp chamber and formation of periapical abscesses were occasionally observed. In case of severe periodontal breakdown, loss of teeth from the mandibles was found. In addition to the inflammatory bone changes, the occurrence of osteofluorotic alterations was also diagnosed in the specimens with the highest bone fluoride concentrations (> 4000 mg F-/kg dry wt). These changes comprised extended apposition of periosteal bone onto the mandibular cortex as well as deformation of the mandibular body, which was attributed to a fluoride-induced osteomalacia. The present study provided circumstantial evidence that, in addition to fluoride induced dental lesions, the occurrence of marked periodontal disease and tooth loss is an important factor responsible for a reduction of life expectancy in severely fluorotic wild red deer.
- MeSH
- dentální fluoróza patologie veterinární MeSH
- fluoridy * MeSH
- mandibula patologie ultrastruktura MeSH
- mikroskopie elektronová rastrovací MeSH
- vysoká zvěř anatomie a histologie MeSH
- znečištění životního prostředí * MeSH
- ztráta zubů chemicky indukované MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
- Německo MeSH
- MeSH
- antibakteriální látky škodlivé účinky terapeutické užití MeSH
- dospělí MeSH
- faryngitida farmakoterapie MeSH
- infekce dýchací soustavy farmakoterapie mikrobiologie MeSH
- lékové předpisy MeSH
- lidé MeSH
- rodinné lékařství MeSH
- tonzilitida farmakoterapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- srovnávací studie MeSH
A macroscopic, microradiographic and scanning electron microscope study was performed on the structure of fluorosed dental enamel in red deer from a fluoride polluted region (North Bohemia, Czech Republic). As was revealed by analysis of mandibular bone fluoride content, the rate of skeletal fluoride accumulation in the fluorotic deer was about 6 times that in controls taken from a region not exposed to excessive fluoride deposition. In all fluorosed mandibles, the 1st molar was consistently less fluorotic than the other permanent teeth. This was related to the fact that crown formation in the M1 takes place prenatally and during the lactation period. Fluorosed teeth exhibited opaque and posteruptively stained enamel, reduction or loss of enamel ridges, moderately to grossly increased wear and, in more severe cases, also enamel surface lesions of partly posteruptive, partly developmental origin. Microradiographically, fluorosed enamel was characterised by subsurface hypomineralisation, interpreted as a result of fluoride interference with the process of enamel maturation. In addition, an accentuation of the incremental pattern due to the occurrence of alternating bands with highly varying mineral content was observed in severely fluorosed teeth, denoting fluoride disturbance during the secretory stage of amelogenesis. A corresponding enhancement of the incremental pattern was also seen in the dentine. The enamel along the more pronounced hypoplasias consisted of stacked, thin layers of crystals arranged in parallel, indicating that the ameloblasts in these locations had lost the distal (prism-forming) portions of their Tomes processes. The findings of the present study indicate that red deer are highly sensitive bioindicators of environmental pollution by fluorides.
- MeSH
- hypoplazie zubní skloviny etiologie patologie veterinární MeSH
- mikroradiografie MeSH
- mikroskopie elektronová rastrovací MeSH
- moláry MeSH
- otrava fluoridy komplikace patologie veterinární MeSH
- vysoká zvěř * MeSH
- znečištění životního prostředí škodlivé účinky MeSH
- zubní sklovina chemie patologie ultrastruktura MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- MeSH
- Arvicolinae krev embryologie MeSH
- biologické markery MeSH
- ekologie MeSH
- hemoglobiny analýza MeSH
- látky znečišťující půdu škodlivé účinky MeSH
- monitorování životního prostředí * metody MeSH
- potrat u zvířat chemicky indukované MeSH
- průmyslový odpad škodlivé účinky MeSH
- těhotenství MeSH
- zvířata MeSH
- Check Tag
- těhotenství MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- Geografické názvy
- Československo MeSH
- MeSH
- infekce bakteriemi řádu Actinomycetales MeSH
- plicní mykózy MeSH
- senioři MeSH
- svaly patologie MeSH
- Check Tag
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
