Adenoidně cystický karcinom je vzácný, pomalu rostoucí, lokálně agresivní salivární maligní tumor, charakterizovaný infiltrativním růstem a vysokým procentem perineurálního šíření. Primární terapeutickou modalitou pro resekabilní salivární tumory je chirurgická léčba. Při peroperačně prokázané neurální invazi je indikována resekce postižené části větvení lícního nervu. Autoři prezentují modifikaci hypoglosso-faciální anastomózy s využitím ansa cervicalis nervi hypoglossi, jako efektivní techniku rekonstrukce periferního větvení lícního nervu s minimální morbiditou v donorské oblasti. Klíčová slova: salivární karcinom, parotidektomie, paréza lícního nervu, rekonstrukce lícního nervu, hypogloso-faciální anastomóza, ansa cevicalis nervi hypoglossi

• Klíčová slova
• parotidektomie, rekonstrukce lícního nervu, hypoglosofaciální anastomóza, ansa cervicalis nervi hypoglossi,
• MeSH
• faciální paralýza etiologie   MeSH
• lidé MeSH
• nádory slinných žláz * diagnóza   chirurgie   radioterapie   MeSH
• nervus facialis chirurgie   patofyziologie   MeSH
• otorinolaryngologické chirurgické výkony metody   MeSH
• senioři MeSH
• výsledek terapie MeSH
• zákroky plastické chirurgie MeSH
• Check Tag
• lidé MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH
• přehledy MeSH

The correct diagnosis of CPA tumours is a relatively common issue in both neurological and ENT practice, the omission of which can have serious consequences for the patient. Properly set clinical guidelines and diagnostic protocols are key aspects of good clinical practice. In the case of CPA tumours, two options are available: the first is diagnosis with the help of an ABR as the primary tool for determining the group of patients with a possible tumour; the second is an MRI scan of the posterior cranial fossa. With an appropriately set diagnostic protocol in place, and despite the 40% chance of failure of the ABR to detect tumours less than or equal to 1 cm, similar treatment results can be achieved with much higher cost efficacy in case of primary ABR testing.

• MeSH
• akustické impedanční testy metody   MeSH
• audiometrie metody   MeSH
• lidé MeSH
• magnetická rezonanční tomografie metody   MeSH
• mostomozečkový úhel * MeSH
• sluchové evokované potenciály fyziologie   MeSH
• vestibulární schwannom diagnóza   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH

• MeSH
• antioxidancia MeSH
• audiometrie MeSH
• biologická variabilita populace MeSH
• cisplatina * aplikace a dávkování   škodlivé účinky   terapeutické užití   MeSH
• Cortiho orgán patofyziologie   patologie   MeSH
• dospělí MeSH
• genotypizační techniky MeSH
• glutathiontransferasa genetika   MeSH
• jednonukleotidový polymorfismus MeSH
• katechol-O-methyltransferasa genetika   MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• nádory farmakoterapie   klasifikace   MeSH
• nemoci ucha chemicky indukované   MeSH
• oxidační stres MeSH
• poruchy sluchu * genetika   chemicky indukované   patologie   MeSH
• prospektivní studie MeSH
• protinádorové látky MeSH
• rizikové faktory MeSH
• testikulární nádory farmakoterapie   MeSH
• tinnitus MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• ženské pohlaví MeSH
• Publikační typ
• práce podpořená grantem MeSH

• MeSH
• diferenciální diagnóza MeSH
• dítě MeSH
• nádory hlavy a krku diagnóza   epidemiologie   patologie   MeSH
• Check Tag
• dítě MeSH

AIM: We designed this study to assess the effect of breastfeeding and its duration on acute otitis media (AOM) in children of our geographical region. Our main aim was to determine the period of breastfeeding, necessary to achieve optimal preventive results against AOM. METHODS: The children that, according to the questionnaire, had suffered AOM infections in the past were used as the study group with the rest of the children used as control. The duration of breastfeeding was divided into months and the odds ratios for the occurrence of AOM were calculated for the children breastfed for more than or equal to a certain period, compared to the children breastfed for less than that period. This was repeated for each month separately and the results plotted on a graph of the confidence interval (CI) for the odds ratio values, against months of breastfeeding. RESULTS: The results of our study show that breastfeeding for a period of up to 11 months can play a significant preventive role against AOM (odds ratio and lower 90% CI > 1). Breastfeeding for longer periods of time is also beneficial, with breastfeeding up to 18 months being associated with some preventive effect against the disease (odds ratio > 1), but the reduction in the incidence of AOM is not statistically significant after the 11th month. Furthermore, there are marked differences in the importance of breastfeeding during the first 11 months, with a vital protective effect during the first 4 months of life which, however, drops by the 5th month and then rises again from the beginning of the 6th to the end of the 8th month. The protective effect then drops once more, although it remains positive and statistically significant until the 11th month of life and positive, but not statistically significant, until the 18th. CONCLUSION: Our study has revealed that for an optimal preventive effect to be achieved, the child should be breastfed for at least the first 11 months of its life. Continuing after this for up to the 18th month shows some preventive effect, which however is not statistically significant. Our results support the hypothesis that the importance of breastfeeding varies with the development of the child, its changing environment and to the new immunological challenges this brings.

• MeSH
• akutní nemoc MeSH
• časové faktory MeSH
• kojenec MeSH
• kojení MeSH
• lidé MeSH
• novorozenec MeSH
• odds ratio MeSH
• otitis media etiologie   prevence a kontrola   MeSH
• studie případů a kontrol MeSH
• Check Tag
• kojenec MeSH
• lidé MeSH
• mužské pohlaví MeSH
• novorozenec MeSH
• ženské pohlaví MeSH
• Geografické názvy
• Česká republika MeSH

This study was designed to examine whether atopy is associated with acute otitis media (AOM). Material and methods: The study was performed with the help of a questionnaire handed out to the parents of 262 children, all residents of Brno, who attended our department for adenoidectomy. The questionnaire was designed to establish any history of atopy and / or AOM in each child, as well as any family history of atopy. The information was compared to the existing data in our database of medical records. The children with one or more AOM events were used as the study group and the children with no AOM infections as a control group. The incidence of atopy in each of these two groups was then statistically analysed. The history of atopy in the family was also compared in each of these two groups. Results: No significant difference was found in the incidence of atopy when children with AOM and children without AOM episodes were compared. Furthermore, no significant difference was found in the family history of atopy, when children with AOM and children without AOM episodes were compared. Conclusion: Our data have shown no connection between AOM episodes and atopy incidence in children or their families, thus atopy or family history of atopy do not seem to play any role in the incidence of AOM.

• MeSH
• adenoidy chirurgie   patologie   MeSH
• alergie etiologie   komplikace   MeSH
• dítě MeSH
• Eustachova trubice imunologie   patologie   MeSH
• imunoglobulin E izolace a purifikace   MeSH
• lidé MeSH
• nemoci imunitního systému diagnóza   etiologie   komplikace   MeSH
• otitis media diagnóza   etiologie   komplikace   MeSH
• průzkumy a dotazníky MeSH
• rizikové faktory MeSH
• statistika jako téma metody   MeSH
• Check Tag
• dítě MeSH
• lidé MeSH