The objective of this prospective, multicentre, non-controlled, open-label study was to evaluate the effects of an iodine-restricted food on circulating total thyroxine (TT4) concentrations and clinical parameters in client-owned cats with hyperthyroidism. Two hundred and twenty-five cats were enrolled in the study and adapted to the iodine-restricted food. Data from physical examinations, questionnaires completed by veterinarians and owners, and circulating concentrations of TT4, urea and creatinine were recorded at weeks 0, 4 and 8. The study group included 136 female and 89 male cats (median age 15 years, range 4-21 years). Group 1 (n = 113) had been on previous anti-thyroid medication, while group 2 (n = 112) consisted of newly diagnosed cats. No differences were found between the two groups at any time point. Circulating TT4 concentrations had decreased (P <0.0001) at week 4 and did not change significantly from week 4 to week 8. Circulating TT4 concentration was within the reference range in 56/88 cats at week 4 and in 51/68 cats at week 8. Clinical parameters (vomiting, polyuria, polydipsia, hyperactivity, polyphagia, weight loss, hair coat quality, and quality of life) had improved (P <0.0001) by week 4. Circulating creatinine concentration decreased (P = 0.001) from week 0 to week 4. Side effects associated with feeding the iodine-restricted food were not observed. In conclusion, in client-owned cats with hyperthyroidism an iodine-restricted food is a valuable management option to normalise circulating TT4 concentrations, and improve clinical signs of hyperthyroidism within 4 weeks. This applies to newly diagnosed cats, as well as to previously diagnosed cats receiving anti-thyroid drugs.

• MeSH
• Animal Nutritional Physiological Phenomena MeSH
• Hyperthyroidism diet therapy   etiology   veterinary   MeSH
• Iodine adverse effects   MeSH
• Cats MeSH
• Animal Feed statistics & numerical data   MeSH
• Cat Diseases diet therapy   etiology   MeSH
• Prospective Studies MeSH
• Animals MeSH
• Check Tag
• Cats MeSH
• Male MeSH
• Female MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Multicenter Study MeSH
• Research Support, Non-U.S. Gov't MeSH

• MeSH
• Aerosols analysis   MeSH
• Nuclear Reactors MeSH
• Beryllium analysis   chemistry   isolation & purification   MeSH
• Wood analysis   MeSH
• Data Interpretation, Statistical MeSH
• Animal Feed analysis   statistics & numerical data   MeSH
• Radiation Monitoring methods   standards   statistics & numerical data   MeSH
• Sewage analysis   statistics & numerical data   MeSH
• Plutonium analysis   chemistry   isolation & purification   MeSH
• Background Radiation adverse effects   MeSH
• Food Contamination, Radioactive analysis   statistics & numerical data   MeSH
• Soil Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Water Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Air Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Radioactive Waste analysis   statistics & numerical data   MeSH
• Radioactive Fallout analysis   statistics & numerical data   MeSH
• Air Pollution, Radioactive analysis   statistics & numerical data   MeSH
• Water Pollution, Radioactive analysis   statistics & numerical data   MeSH
• Cesium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Potassium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Krypton Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Lead Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Strontium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Carbon Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Tritium analysis   chemistry   isolation & purification   MeSH
• Publication type
• Annual Report MeSH
• Geographicals
• Czech Republic MeSH

• MeSH
• Aerosols analysis   MeSH
• Nuclear Reactors MeSH
• Beryllium analysis   chemistry   isolation & purification   MeSH
• Wood analysis   MeSH
• Data Interpretation, Statistical MeSH
• Animal Feed analysis   statistics & numerical data   MeSH
• Radiation Monitoring methods   standards   statistics & numerical data   MeSH
• Hazardous Waste analysis   statistics & numerical data   MeSH
• Sewage analysis   statistics & numerical data   MeSH
• Plutonium analysis   chemistry   isolation & purification   MeSH
• Background Radiation adverse effects   MeSH
• Radioactivity MeSH
• Food Contamination, Radioactive analysis   statistics & numerical data   MeSH
• Soil Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Water Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Air Pollutants, Radioactive chemistry   isolation & purification   MeSH
• Radioactive Fallout analysis   statistics & numerical data   MeSH
• Air Pollution, Radioactive analysis   statistics & numerical data   MeSH
• Water Pollution, Radioactive analysis   statistics & numerical data   MeSH
• Cesium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Potassium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Krypton Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Lead Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Strontium Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Carbon Radioisotopes analysis   chemistry   isolation & purification   MeSH
• Tritium analysis   chemistry   isolation & purification   MeSH
• Publication type
• Annual Report MeSH
• Geographicals
• Czech Republic MeSH