Background: We present our current approaches to improving personal data protection in (i) large (regional/ national/international) scale health information exchanges (HIEs) and (ii) UK NHS IG toolkit and ISO 27001-compliant trustworthy research environments (TREs) for discovery science communities. In particular we examine impacts of the General Data Protection Regulation (GDPR) on these technology designs and developments and the responses we have made to control complexity. Methods: The paper discusses multiple requirements to implement the key GDPR principles of “data protection by design” and “data protection by default”, each requiring new capabilities to embed multiple security tests and data protection tools in common deployable infrastructures. Methods are presented for consistent implementation of diverse data processing use cases. Results: We describe how modular compositions of GDPRcompliant data processing software have been used to implement use case(s) and deliver information governance (IG) requirements transparently. Security surveillance analysis is embedded throughout the application lifecycle, namely at design, implementation and operation (runtime) phases. A solution is described to the challenge of integrating coherent research (analytic) environments for authorized researchers to access data and analytic tools without compromising security or privacy. Conclusion: We recognise the need for wider implementation of rigorous interoperability standards concerning privacy and security management. Standards can be disseminated within low-cost commodity infrastructures that are shared across consortium partners. Comprehensive model-based approaches to information management will be fundamental to guaranteeing security and privacy in challenging areas such as ethical use of artificial intelligence in medicine. The target architecture is still in evolution but needs a number of communitycollaborative API developments to couple advanced specifications fulfilling all IG requirements.
- MeSH
- 2D gelová elektroforéza metody přístrojové vybavení využití MeSH
- automatizované zpracování dat metody normy MeSH
- Bacteria MeSH
- bakteriologické techniky metody využití MeSH
- Borrelia burgdorferi komplex genetika imunologie MeSH
- Borrelia genetika imunologie MeSH
- klíště MeSH
- lymeská nemoc diagnóza etiologie mikrobiologie MeSH
- proteiny izolace a purifikace MeSH
- proteomika metody MeSH
- spektrometrie hmotnostní - ionizace laserem za účasti matrice metody přístrojové vybavení využití MeSH
- MeSH
- automatizované zpracování dat normy MeSH
- falešně negativní reakce MeSH
- lidé MeSH
- triglyceridy krev MeSH
- Check Tag
- lidé MeSH
- MeSH
- agregace trombocytů genetika imunologie MeSH
- automatizované zpracování dat normy MeSH
- citráty MeSH
- dospělí MeSH
- EDTA MeSH
- lidé středního věku MeSH
- lidé MeSH
- odběr vzorku krve normy MeSH
- senioři MeSH
- trombocytopenie diagnóza MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
258 s. : il. ; 21 cm
