BACKGROUND: Verbal memory is an essential cognitive ability with scope for adequate treatment of information and for orientation in everyday life. Our study is centered on memory performance in the wake of treatment for ruptured intracranial aneurysm. METHODS: Three psychological tests were performed: (1) within a month of the neurosurgical intervention, (2) 1 year and (3) 5-7 years after the ruptured aneurysm treatment. Under comparison are the overall results of tests for verbal memory capacity in a cohort of patients (N = 59) and in the control group. RESULTS: Three post-treatment measurements revealed a persistent deficit of verbal memory. The cohort's average performance improved from -1.3 SD (standard deviation) below the average of the norm to -0.5 SD below the norm at the second test 1 year after treatment, while at the third test the deficit had worsened to -0.68 SD. Similarly, testing for long-term recovery at 5-7 years postoperatively showed the patients' performances to be 2/3 SD below the average of the general population. CONCLUSIONS: The results of the study imply the need for long-term rehabilitation of memory in this particular group of patients.
- MeSH
- dospělí MeSH
- intrakraniální aneurysma epidemiologie rehabilitace chirurgie MeSH
- jazykové poruchy diagnóza epidemiologie rehabilitace MeSH
- kohortové studie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- následné studie MeSH
- poruchy paměti diagnóza epidemiologie rehabilitace MeSH
- prasklé aneurysma epidemiologie rehabilitace chirurgie MeSH
- retrospektivní studie MeSH
- senioři MeSH
- subarachnoidální krvácení epidemiologie rehabilitace chirurgie MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
The aim of this study was to categorize speech problems in autistic children in a manner allowing recognition of associated risk factors. We were specifically interested in the role of epilepsy and epileptiform activity in EEG in autistic patients since these dynamic processes can influence each other. We combined subtypes of autism with degrees of their functionality and we selected three speech endpoints: i) delayed development of speech, ii) complete mutism and iii) regression of speech. We retrospectively examined 205 autistic children (boys 145/70.7%, mean age 10 years). Median IQ was 55 (15;104) and median Childhood Autism Rating Scale (CARS) ranged within 38 (32;48). Univariate and multivariate logistic regression helped to define clinical and diagnostic factors that were significantly associated with speech endpoints. Epileptic seizures, epileptiform EEG abnormalities, non-right-handedness, hypotonia and severe decreased IQ score were found to be the most important mutually independent factors contributing to the increased risk of speech-related problems in patients with ASD.
- MeSH
- autistická porucha epidemiologie patofyziologie MeSH
- dítě MeSH
- elektroencefalografie MeSH
- epilepsie epidemiologie patofyziologie MeSH
- funkční lateralita MeSH
- jazykové poruchy diagnóza epidemiologie MeSH
- jazykové testy MeSH
- kognitivní poruchy diagnóza epidemiologie MeSH
- lidé MeSH
- neuropsychologické testy MeSH
- retrospektivní studie MeSH
- stupeň závažnosti nemoci MeSH
- svalová hypotonie epidemiologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- MeSH
- epidemiologické studie * MeSH
- jazykové poruchy diagnóza epidemiologie MeSH
- klinická logopedie metody MeSH
- koktavost diagnóza epidemiologie MeSH
- lidé MeSH
- plošný screening * MeSH
- poruchy řeči * diagnóza epidemiologie MeSH
- předškolní dítě MeSH
- školky MeSH
- školy MeSH
- statistika jako téma MeSH
- Check Tag
- lidé MeSH
- předškolní dítě MeSH
- Geografické názvy
- Jugoslávie MeSH