PURPOSE: To compare 3 capsulotomy centration methods. SETTING: Private clinic, Zlin, Czech Republic. DESIGN: Prospective, consecutive case series. METHODS: 180 eyes undergoing cataract surgery had anterior capsule staining with microfiltered 0.4% trypan blue solution before selective laser capsulotomy. The first 60 eyes (Group 1) had mydriatic dilated pupil centered capsulotomies. The next 60 eyes (Group 2) were centered on the trypan blue central landmark (TCL). The final 60 capsulotomies (Group 3) were centered on the patient fixated coaxial Purkinje reflex (CPR). Measurements between key anatomical landmarks and the TCL, CPR capsulotomies, and implanted intraocular lens (IOL) center were made. RESULTS: The TCL, observed in >94% of eyes in the study, coincided with the CPR with a displacement of <0.1 ± 0.1 mm. Group 1 capsulotomies were noticeably decentered on the IOLs by 0.3 ± 0.2 mm. The Group 2 symmetrical IOL relationship was maintained with a decentration of 0.15 ± 0.1 mm. Group 3 had a similar decentration with the IOLs with 0.15 ± 0.1 mm. Verification with IOLMaster 700 data and CALLISTO Eye System showed that the CPR and the TCL were coincident with the measured visual axis. CONCLUSIONS: The clearly visible TCL served as an alternate landmark to the patient fixated CPR, and being on the anterior capsule was not sensitive to tilt. Further patient compliance was not required. Both were superior to dilated pupil centration, to achieve symmetric IOL coverage. This has application for both capsulotomies and capsulorhexes.

• MeSH
• Anatomic Landmarks MeSH
• Coloring Agents * administration & dosage   MeSH
• Capsulorhexis * methods   MeSH
• Phacoemulsification * MeSH
• Lens Implantation, Intraocular MeSH
• Middle Aged MeSH
• Humans MeSH
• Lens Capsule, Crystalline surgery   MeSH
• Anterior Capsule of the Lens surgery   MeSH
• Prospective Studies MeSH
• Aged, 80 and over MeSH
• Aged MeSH
• Trypan Blue * MeSH
• Check Tag
• Middle Aged MeSH
• Humans MeSH
• Male MeSH
• Aged, 80 and over MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Research Support, Non-U.S. Gov't MeSH
• Comparative Study MeSH

AIMS: The aim of this study was to evaluate the changes in IOL position (axial shift, tilt and decentration) in the capsular bag after Nd:YAG laser capsulotomy and to create a user-friendly software that is optimized for the output of available imaging technology, then verify the relationship between the biometric parameters of the eye and the extent of changes in the IOL position. PATIENTS AND METHODS: The study included 35 artephakic eyes that underwent laser capsulotomy. Before and at least one hour after capsulotomy, all patients underwent the following assessments: optical biometry (Lenstar LS900), OCT with anterior segment module (Optovue Avanti) and IOL photography in infrared mode using reference unit (Verion). The original software solution was designed for the graphical evaluation of the differences between centering, axial displacement and tilt of IOL. Changes in IOL position were evaluated as simple differences before and after the laser procedure and as differences in absolute values (abs). RESULTS: The following results show the average differences in IOL position: ACD=0.02±0.23 mm (abs=0.11±0.20 mm), IOL decentration in x-axis = -0.001±0.091 mm (abs=0.065±0.063 mm), IOL decentration in y-axis =0.012±0.119 mm (abs=0.048±0.53 mm), tilt in horizontal plane TILT-H=0.11±0.83° (abs=0.51±0.66°) and tilt in vertical plane TILT-V = -0.14±0.49° (abs=0.26±0.44°). All changes were insignificant (P>>0.05). In total, 74.29% of IOLs showed a hypermetropic shift. A moderate positive correlation was found between the absolute differences in horizontal tilt and keratometry (r=0.45). Relationship with other changes and parameters were weak. CONCLUSION: In conclusion, the use of the original software solution developed by the authors showed that changes in IOL centering, axial displacement and tilt occur after Nd:YAG capsulotomy, but average differences were insignificant. In almost 3/4 cases, there was a hypermetropic axial displacement of the IOL.

• MeSH
• Phacoemulsification * MeSH
• Lens Implantation, Intraocular methods   MeSH
• Laser Therapy * MeSH
• Humans MeSH
• Lenses, Intraocular * MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH

Electronic Health Record (EHR) systems currently in use are not designed for widely interoperable longitudinal health data. Therefore, EHR data cannot be properly shared, managed and analyzed. In this article, we propose two approaches to making EHR data more comprehensive and FAIR (Findable, Accessible, Interoperable, and Reusable) and thus more useful for diagnosis and clinical research. Firstly, the data modeling based on the LinkML framework makes the data interoperability more realistic in diverse environments with various experts involved. We show the first results of how diverse health data can be integrated based on an easy-to-understand data model and without loss of available clinical knowledge. Secondly, decentralizing EHRs contributes to the higher availability of comprehensive and consistent EHR data. We propose a technology stack for decentralized EHRs and the reasons behind this proposal. Moreover, the two proposed approaches empower patients because their EHR data can become more available, understandable, and usable for them, and they can share their data according to their needs and preferences. Finally, we explore how the users of the proposed solution could be involved in the process of its validation and adoption.

• MeSH
• Data Management MeSH
• Electronic Health Records * MeSH
• Humans MeSH
• Semantic Web * MeSH
• Software MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH

• MeSH
• Bioethics MeSH
• Abortion, Induced * ethics   MeSH
• Humans MeSH
• Religion MeSH
• Politics MeSH
• Check Tag
• Humans MeSH

• MeSH
• Bioethics MeSH
• Abortion, Induced * ethics   MeSH
• Humans MeSH
• Religion MeSH
• Politics MeSH
• Check Tag
• Humans MeSH

• MeSH
• National Health Programs MeSH
• Health Policy MeSH
• Health Planning MeSH

• Conspectus
• Veřejné zdraví a hygiena
• NML Fields
• veřejné zdravotnictví
• NML Publication type
• publikace WHO

• MeSH
• Delivery of Health Care MeSH
• Health Services Administration MeSH
• Family Planning Services MeSH
• Reproductive Health Services organization & administration   MeSH

• Conspectus
• Veřejné zdraví a hygiena
• NML Fields
• reprodukční lékařství
• veřejné zdravotnictví
• NML Publication type
• publikace WHO

• MeSH
• Cataract MeSH
• Clinical Medicine MeSH
• Lens Diseases MeSH
• Ophthalmology MeSH
• Science MeSH

• Conspectus
• Učební osnovy. Vyučovací předměty. Učebnice
• Ortopedie. Chirurgie. Oftalmologie
• NML Fields
• oftalmologie
• věda a výzkum
• NML Publication type
• učebnice vysokých škol

• MeSH
• Mathematics MeSH
• Game Theory MeSH
• Publication type
• Monograph MeSH

• Conspectus
• Matematika
• NML Fields
• přírodní vědy

• MeSH
• Delivery of Health Care MeSH
• Primary Health Care MeSH
• Community Health Services organization & administration   MeSH

• Conspectus
• Veřejné zdraví a hygiena
• NML Fields
• veřejné zdravotnictví
• management, organizace a řízení zdravotnictví
• NML Publication type
• publikace WHO