• MeSH
• karcinom chirurgie   MeSH
• laserová terapie MeSH
• lasery MeSH
• nádory ženských pohlavních orgánů chirurgie   MeSH
• nemoci vulvy chirurgie   MeSH
• oxid uhličitý MeSH
• vaginální onemocnění chirurgie   MeSH

BACKGROUND: Incidence of cervical cancer has been reduced by organized screening while for vaginal and vulvar cancers no systematic screening has been implemented. All these cancers are associated with human papilloma virus (HPV) infection. We wanted to analyze incidence trends and relative survival in these cancers with specific questions about the possible covariation of incidence, survival changes coinciding with incidence changes and the role of treatment in survival. We used nationwide cancer registry data for Denmark (DK), Finland (FI), Norway (NO) and Sweden (SE) to address these questions. METHODS: We use the NORDCAN database for the analyses: incidence data were available from 1943 in DK, 1953 in FI and NO and 1960 in SE, through 2016. Survival data were available from 1967 through 2016. World standard population was used in age standardization. RESULTS: In each country the incidence of cervical cancer declined subsequent to rolling out of screening activities. The attained plateau incidence was lowest at 4/100,000 in FI and highest at 10/100,000 in DK and NO. The incidence of vaginal and vulvar cancer remained relatively constant at about 2/100,000. Relative 1-year survival in cervical cancer improved in all countries from low 80%s to high 80%s in the 50-year period, and 5-year survival improved also but at 20% units lower level. Survival gains were found only in patients diagnosed before age 60 years. Survival in vaginal and vulvar cancer followed the same patterns but at a few % units lower level. CONCLUSION: Cervical cancer screening appeared to have reached its limits in the Nordic countries by year 2000. Novel treatments, such as immunotherapy, would be needed to improve survival until HPV vaccination will reach population coverage and boost the global fight against these cancers.

• MeSH
• časná detekce nádoru MeSH
• incidence MeSH
• infekce papilomavirem * MeSH
• lidé středního věku MeSH
• lidé MeSH
• nádory děložního čípku * prevence a kontrola   terapie   MeSH
• nádory vulvy * epidemiologie   terapie   MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Dánsko MeSH
• Finsko MeSH
• Norsko MeSH
• Švédsko MeSH

• MeSH
• nádory děložního čípku MeSH
• nádory vaginy MeSH
• nádory vulvy MeSH
• nádory ženských pohlavních orgánů farmakoterapie   chirurgie   radioterapie   MeSH
• Publikační typ
• atlasy MeSH

• Konspekt
• Lékařské vědy. Lékařství
• NLK Obory
• gynekologie a porodnictví
• onkologie

• MeSH
• lidé MeSH
• nádory vulvy MeSH
• Papillomaviridae izolace a purifikace   MeSH
• polymerázová řetězová reakce MeSH
• vaginální stěr mikrobiologie   MeSH
• vaginální výtok mikrobiologie   MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH

• MeSH
• nádory vaginy klasifikace   patologie   MeSH
• nádory vulvy klasifikace   patologie   MeSH
• nádory ženských pohlavních orgánů klasifikace   patologie   MeSH
• Publikační typ
• monografie MeSH

• Konspekt
• Gynekologie. Porodnictví
• NLK Obory
• gynekologie a porodnictví
• onkologie

• MeSH
• nádory děložního čípku patologie   MeSH
• nádory vaginy patologie   MeSH
• nádory vulvy patologie   MeSH
• Publikační typ
• atlasy MeSH

• Konspekt
• Patologie. Klinická medicína
• NLK Obory
• onkologie
• gynekologie a porodnictví
• patologie

• MeSH
• gestační trofoblastická nemoc genetika   klasifikace   patologie   MeSH
• ligamentum latum uteri patologie   MeSH
• nádory dělohy genetika   klasifikace   patologie   MeSH
• nádory vaginy genetika   klasifikace   patologie   MeSH
• nádory vaječníků genetika   klasifikace   patologie   MeSH
• nádory vejcovodů genetika   klasifikace   patologie   MeSH
• nádory vulvy genetika   klasifikace   patologie   MeSH
• nádory ženských pohlavních orgánů genetika   klasifikace   patologie   MeSH
• peritoneální nádory genetika   klasifikace   patologie   MeSH
• Publikační typ
• směrnice pro lékařskou praxi MeSH

• Konspekt
• Gynekologie. Porodnictví
• NLK Obory
• gynekologie a porodnictví
• onkologie
• NLK Publikační typ
• publikace WHO

• MeSH
• incidence MeSH
• lidé MeSH
• nádory vaginy epidemiologie   terapie   MeSH
• nádory vulvy epidemiologie   terapie   MeSH
• staging nádorů MeSH
• Check Tag
• lidé MeSH
• ženské pohlaví MeSH

• MeSH
• lékařská onkologie metody   trendy   MeSH
• management bolesti MeSH
• management nemoci MeSH
• nádory diagnóza   epidemiologie   etiologie   terapie   MeSH

• Konspekt
• Patologie. Klinická medicína
• NLK Obory
• onkologie
• NLK Publikační typ
• kolektivní monografie

Vaginal dryness (VD) affects both pre- and postmenopausal women at any age. Since the hormonal regulation changes during the climacteric period are considered as being the main course of the VD, affected women prefer not to talk about the problem. However, the problem does exist, and unfortunately if any, relatively minor group in the population possesses the health literacy at sufficient level to understand that VD is a suboptimal health condition which carries a multi-factorial character. Thereby, some of the contributing factors are clearly preventable and, therefore, if treated properly, have a potential to milden the VD. Current chapter demonstrates specific signs and symptoms of Flammer syndrome in women suffering from vaginal dryness, although individualised patient profiles clearly discriminate between pre- and postmenopausal women regarding the subgroup-specific symptoms. Noteworthy, about 20% of the VD patients involved in the study notify a delayed or even impaired wound healing observed for themselves over a couple of years. Optimising modifiable risk factors accompanying FS phenotype at the level of primary prevention is strongly recommended. Individualised patient profiles provide important information for VD mitigating measures tailored to the person. Further, future projects should essentially deal with the complexity of vulvar-vaginal dryness as part of the Sicca syndrome in individuals with FS phenotype, in order to prevent genital female cancers which may occur at any age. In contrast to the human papilloma virus as possible trigger of the disease, the role of the vulvar-vaginal dryness as an important risk factor is strongly underestimated in currently applied diagnostic and treatment approaches.

• Publikační typ
• časopisecké články MeSH