Steroid 11-beta-Hydroxylase [steroid-11-beta-hydroxylasa]
- Terms
-
CYP 11B1
CYP11B1
cytochrom P-450 11B1
cytochrom P-450(11 beta)
cytochrom P450 11B1
steroid-11-beta-hydroxyláza
steroid-11-beta-monooxygenasa
-
11 beta-Hydroxylase
CYP 11B1
CYP11B1
Cytochrome P-450 CYP11B1
Cytochrome P-450(11 beta)
Cytochrome P450 11B1
Steroid 11 Hydroxylase
Steroid 11-beta-Monooxygenase
Steroid 11-Hydroxylase
Steroid-11-Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
- DUI
- D013252 MeSH Browser
- CUI
- M0020521
- CAS
- Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
- Previous indexing
- Steroid Hydroxylases (1973-1977)
- History note
- 2003 (1978)
- Public note
- 2003; see STEROID 11 BETA-MONOOXYGENASE 1997-2002, see STEROID 11-HYDROXYLASE 1991-1996, see STEROID HYDROXYLASES 1990, see STEROID-11-HYDROXYLASE 1978-1989
Combination
- deficiency
- Adrenal Hyperplasia, Congenital
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