steroid-11-beta-hydroxylasa [Steroid 11-beta-Hydroxylase]

tematický
3
Termíny

CYP 11B1
CYP11B1
cytochrom P-450 11B1
cytochrom P-450(11 beta)
cytochrom P450 11B1
steroid-11-beta-hydroxyláza
steroid-11-beta-monooxygenasa

 

11 beta-Hydroxylase
CYP 11B1
CYP11B1
Cytochrome P-450 CYP11B1
Cytochrome P-450(11 beta)
Cytochrome P450 11B1
Steroid 11 Hydroxylase
Steroid 11-beta-Monooxygenase
Steroid 11-Hydroxylase
Steroid-11-Hydroxylase

Perzistentní odkaz   https://www.medvik.cz/link/D013252
Definice

Mitochondriální enzym cytochromu P450, který katalyzuje 11-beta-hydroxylaci steroidů za přítomnosti molekulárního kyslíku a NADPH-cytochrom c-reduktázy. Tento enzym, kódovaný genem CYP11B1, je důležitý při syntéze kortikosteronu a hydrokortisonu. Defekty CYP11B1 způsobují kongenitální adrenální hyperplazii.

A mitochondrial cytochrome P450 enzyme that catalyzes the 11-beta-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP11B1 gene, is important in the synthesis of CORTICOSTERONE and HYDROCORTISONE. Defects in CYP11B1 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).

DUI
D013252 MeSH Prohlížeč
CUI
M0020521
CAS
Steroid, reduced-adrenal-ferredoxin:oxygen oxidoreductase (11 beta-hydroxylating)
Předchozí užití
Steroid Hydroxylases (1973-1977)
Historická pozn.
2003 (1978)
Veřejná pozn.
2003; see STEROID 11 BETA-MONOOXYGENASE 1997-2002, see STEROID 11-HYDROXYLASE 1991-1996, see STEROID HYDROXYLASES 1990, see STEROID-11-HYDROXYLASE 1978-1989

Kombinace

nedostatek
kongenitální adrenální hyperplazie

Povolená podhesla

AN
analýza
AI
antagonisté a inhibitory 1
AD
aplikace a dávkování 1
BI
biosyntéza
CS
chemická syntéza
CH
chemie
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie
PH
fyziologie
GE
genetika 1
IM
imunologie
IP
izolace a purifikace
CL
klasifikace
BL
krev
ME
metabolismus
UR
moč
CF
mozkomíšní mok
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití 1
TO
toxicita
DE
účinky léků
RE
účinky záření
UL
ultrastruktura
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.244 cytochromy 121
D08.244.453 systém (enzymů) cytochromů P-450 692
D08.244.453.484 rodina 11 cytochromu P450
D08.244.453.484.250 enzym štěpící postranní řetězce cholesterolu 6
D08.244.453.484.500 cytochrom P450 CYP11B2 11
D08.244.453.484.750 steroid-11-beta-hydroxylasa 3
D08.244.453.915 steroidhydroxylasy 16
D08.244.453.915.025 cholesterol-24-hydroxylasa
D08.244.453.915.050 cytochrom P450 CYP11B2 11
D08.244.453.915.099 aromatasa 72
D08.244.453.915.149 cytochrom P450 CYP271 4
D08.244.453.915.200 cholesterol-7-alfa-hydroxylasa 19
D08.244.453.915.212 enzym štěpící postranní řetězce cholesterolu 6
D08.244.453.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 4
D08.244.453.915.730 steroid-12-alfa-hydroxylasa 1
D08.244.453.915.737 steroid-16-alfa-hydroxylasa 5
D08.244.453.915.748 steroid-17-alfa-hydroxylasa 21
D08.244.453.915.750 steroid-11-beta-hydroxylasa 3
D08.244.453.915.760 steroid-21-hydroxylasa 64
D08.244.453.915.880 sterol-14-demethylasa 2
D08.811 enzymy 1 551
D08.811.682 oxidoreduktasy 446
D08.811.682.690 oxygenasy 76
D08.811.682.690.708 oxygenasy se smíšenou funkcí 68
D08.811.682.690.708.170 systém (enzymů) cytochromů P-450 692
D08.811.682.690.708.170.425 rodina 11 cytochromu P450
D08.811.682.690.708.170.425.250 enzym štěpící postranní řetězce cholesterolu 6
D08.811.682.690.708.170.425.500 cytochrom P450 CYP11B2 11
D08.811.682.690.708.170.425.750 steroid-11-beta-hydroxylasa 3
D08.811.682.690.708.170.915 steroidhydroxylasy 16
D08.811.682.690.708.170.915.025 cholesterol-24-hydroxylasa
D08.811.682.690.708.170.915.050 cytochrom P450 CYP11B2 11
D08.811.682.690.708.170.915.099 aromatasa 72
D08.811.682.690.708.170.915.150 cytochrom P450 CYP271 4
D08.811.682.690.708.170.915.200 cholesterol-7-alfa-hydroxylasa 19
D08.811.682.690.708.170.915.212 enzym štěpící postranní řetězce cholesterolu 6
D08.811.682.690.708.170.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 4
D08.811.682.690.708.170.915.730 steroid-12-alfa-hydroxylasa 1
D08.811.682.690.708.170.915.737 steroid-16-alfa-hydroxylasa 5
D08.811.682.690.708.170.915.748 steroid-17-alfa-hydroxylasa 21
D08.811.682.690.708.170.915.750 steroid-11-beta-hydroxylasa 3
D08.811.682.690.708.170.915.760 steroid-21-hydroxylasa 64
D08.811.682.690.708.170.915.880 sterol-14-demethylasa 2
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 581
D12.776.422 hemoproteiny 16
D12.776.422.220 cytochromy 121
D12.776.422.220.453 systém (enzymů) cytochromů P-450 692
D12.776.422.220.453.484 rodina 11 cytochromu P450
D12.776.422.220.453.484.250 enzym štěpící postranní řetězce cholesterolu 6
D12.776.422.220.453.484.500 cytochrom P450 CYP11B2 11
D12.776.422.220.453.484.750 steroid-11-beta-hydroxylasa 3
D12.776.422.220.453.915 steroidhydroxylasy 16
D12.776.422.220.453.915.025 cholesterol-24-hydroxylasa
D12.776.422.220.453.915.050 cytochrom P450 CYP11B2 11
D12.776.422.220.453.915.099 aromatasa 72
D12.776.422.220.453.915.150 cytochrom P450 CYP271 4
D12.776.422.220.453.915.200 cholesterol-7-alfa-hydroxylasa 19
D12.776.422.220.453.915.212 enzym štěpící postranní řetězce cholesterolu 6
D12.776.422.220.453.915.400 1-alfa-hydroxylasa 25-hydroxyvitaminu D3 4
D12.776.422.220.453.915.730 steroid-12-alfa-hydroxylasa 1
D12.776.422.220.453.915.737 steroid-16-alfa-hydroxylasa 5
D12.776.422.220.453.915.748 steroid-17-alfa-hydroxylasa 21
D12.776.422.220.453.915.750 steroid-11-beta-hydroxylasa 3
D12.776.422.220.453.915.760 steroid-21-hydroxylasa 64
D12.776.422.220.453.915.880 sterol-14-demethylasa 2

Cyp11c1 protein, zebrafish Chemical MeSH Prohlížeč

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