Wolman Disease [Wolmanova nemoc]

topical
15
Terms

deficience lyzosomální kyselé lipázy
deficit kyselé lipázy
deficit lyzosomální kyselé lipázy
familiární xantomatóza
Wolmanova choroba
Wolmanova xantomatóza

 

Acid Cholesteryl Ester Hydrolase Deficiency, Type 2
Acid Cholesteryl Ester Hydrolase Deficiency, Wolman Type
Acid Lipase Deficiency
Acid Lipase Disease
Cholesterol ester hydrolase deficiency
Familial Xanthomatosis
LAL Deficiency
LIPA Deficiency
Liposomal Acid Lipase Deficiency, Wolman Type
Lysosomal Acid Lipase Deficiency
Wolman Disease with Hypolipoproteinemia and Acanthocytosis
Wolman's Disease
Xanthomatosis, Familial
Xanthomatosis, Wolman's

Persistent link   https://www.medvik.cz/link/D015223
Definition

The severe infantile form of inherited lysosomal lipid storage diseases due to deficiency of acid lipase (STEROL ESTERASE). It is characterized by the accumulation of neutral lipids, particularly CHOLESTEROL ESTERS in leukocytes, fibroblasts, and hepatocytes. It is also known as Wolman's xanthomatosis and is an allelic variant of CHOLESTEROL ESTER STORAGE DISEASE.

DUI
D015223 MeSH Browser
CUI
M0023386
Previous indexing
Cholesterol Esters (1978-1988); Lipase (1966-1988); Lipid Metabolism, Inborn Errors (1966-1988); Lipoidosis (1966-1988); Xanthomatosis (1966-1988)
History note
1989
Public note
1989

C Diseases
C16.320.565.398.641 Lipidoses 35
C16.320.565.398.641.201 Cholesterol Ester Storage Disease 13
C16.320.565.398.641.201.500 Wolman Disease 15
C16.320.565.595 Lysosomal Storage Diseases 72
C16.320.565.595.201.500 Wolman Disease 15
C16.614.053 Anemia, Neonatal 22
C16.614.092 Asphyxia Neonatorum 172
C16.614.131 Birth Injuries 158
C16.614.166 Colic 125
C16.614.213 Cystic Fibrosis 1 328
C16.614.378 Hernia, Umbilical 45
C16.614.438 Hydrophthalmos 9
C16.614.492 Ichthyosis 62
C16.614.595 Mobius Syndrome 10
C16.614.627 Neonatal Sepsis 35
C16.614.660 OEIS Complex
C16.614.810 Sclerema Neonatorum 2
C16.614.868 Syphilis, Congenital 87
C16.614.947 Wolman Disease 15
C18.452 Metabolic Diseases 1 196
C18.452.584.563.641 Lipidoses 35
C18.452.584.563.641.201 Cholesterol Ester Storage Disease 13
C18.452.584.563.641.201.500 Wolman Disease 15
C18.452.648.398.641 Lipidoses 35
C18.452.648.398.641.201 Cholesterol Ester Storage Disease 13
C18.452.648.398.641.201.500 Wolman Disease 15
C18.452.648.595 Lysosomal Storage Diseases 72
C18.452.648.595.201.500 Wolman Disease 15