Alveolárna echinokokóza (AE) je agresívna a potenciálne fatálna parazitárna zoonóza. Jejpôvodcom je Echinococcus multilocularis.U človeka býva primárne postihnutá pečeň. Ocho-renie je typické svojím infiltratívnym rastom a metastatickým šírením, čím napodobňuje ma-lignitu. Multiorgánová invázia je pozorovaná v približne 13 % prípadov. Lokálne môže infil-trovať vaskulárne štruktúry, biliárny systém a hilus pečene. Imunosupresívna liečba podporujeprogresiu tohto infekčného ochorenia. V prípade postihnutia vaskulárnych štruktúr dokážeimitovať a podporovať trombotický proces. V kazuistike prezentujeme prípad pacientky sosclerosis multiplex na biologickej liečbe alemtuzumabom spojenej s opakovanou pulznoulieč bou kortikoidmi, u ktorej došlo ku závažnej lokálnej progresii echinokokózy s prerastanímdo dolnej dutej žily.
Alveolar echinococcosis (AE) is an aggressive and potentially fatal parasite zoonosis. It iscaused by Echinococcus multilocularis. It primarily affects liver in humans. The disease is typi -cally manifested by an infiltrative growth and a metastatic spread that imitates malignancy.The multiorgan invasion is observed in about 13 % of cases. It may locally infiltrate vascularstructures, biliary system and hepatic hilus. The immunosuppressive treatment acceleratesthe progression of this infective disease. When vascular system is affected the disease mayimitate and accelerate the thrombotic process. We present a case report of a patient with mul-tiple sclerosis treated with a biologic treatment alemtuzumab and repeated pulses of corti-costeroid therapy who experienced a severe local progression of echinococcosis with a spreadto the inferior vena cava.
- MeSH
- Alemtuzumab pharmacology immunology therapeutic use MeSH
- Adult MeSH
- Echinococcus granulosus isolation & purification MeSH
- Echinococcosis, Hepatic * diagnostic imaging epidemiology complications MeSH
- Humans MeSH
- Multiple Sclerosis drug therapy MeSH
- Iliac Vein diagnostic imaging microbiology pathology MeSH
- Venous Thrombosis surgery diagnostic imaging etiology MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Abdomen, Acute MeSH
- Humans MeSH
- Kidney Neoplasms complications MeSH
- Nephrectomy MeSH
- Kidney Diseases MeSH
- Rupture, Spontaneous MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- MeSH
- Adult MeSH
- Phlebography methods MeSH
- Heparin administration & dosage MeSH
- Humans MeSH
- Postoperative Complications diagnosis therapy MeSH
- Streptokinase administration & dosage MeSH
- Thrombosis diagnosis drug therapy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Case Reports MeSH
- Comparative Study MeSH
- MeSH
- Biomedical Research MeSH
- Pancreatic Neoplasms surgery MeSH
- Pancreatectomy mortality MeSH
- Publication type
- Case Reports MeSH
