PURPOSE: The study evaluates the rate of postoperative formation of a pupillary membrane (PM) and posterior visual axis opacification (PVAO) in infants with and without primary IOL implantation during the first 4 months of infancy. METHODS: Medical records for 144 eyes (101 infants) operated between 2005 and 2014 were evaluated. A posterior capsulectomy and anterior vitrectomy were performed. Primary IOL implantation was performed in 68 eyes, while 76 eyes were left aphakic. There were 16 bilateral cases in the pseudophakic group and 27 in the aphakic group. The follow-up period was 54.3 ± 21.05 months and 49.1 ± 18.60 months, respectively. Fisher's exact test was used for statistical analysis. The two-sample t-test with equal variance was used to compare surgery age, follow-up period and time intervals of complications. RESULTS: The mean age of surgery was 2.1 ± 0.85 months in the pseudophakic and 2.2 ± 1.01 months in the aphakic group. PM was diagnosed in 40% pseudophakic and 7% aphakic eyes. A second surgery for PVAO was performed in 72% pseudophakic and 16% aphakic eyes. Both were significantly higher in the pseudophakic group. In the pseudophakic group, the number of PVAO was significantly higher in infants operated before 8 weeks of age compared to surgery age 9-16 weeks. The frequency of PM was not age-dependent. CONCLUSION: Although it remains feasible to implant an IOL during the primary surgery, even in very young infants, there should always be solid arguments for this decision since it puts the child at higher risk of repeated surgeries under general anaesthesia.
- MeSH
- Aphakia * complications MeSH
- Child MeSH
- Cataract Extraction * adverse effects MeSH
- Lens Implantation, Intraocular adverse effects MeSH
- Cataract * congenital MeSH
- Infant MeSH
- Humans MeSH
- Follow-Up Studies MeSH
- Lenses, Intraocular * adverse effects MeSH
- Postoperative Complications epidemiology MeSH
- Retrospective Studies MeSH
- Visual Acuity MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Publication type
- Journal Article MeSH
- MeSH
- Aphakia * therapy MeSH
- Lens Implantation, Intraocular * MeSH
- Data Interpretation, Statistical MeSH
- Cataract MeSH
- Infant MeSH
- Contact Lenses * utilization MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Postoperative Complications MeSH
- Postoperative Care MeSH
- Prospective Studies MeSH
- Randomized Controlled Trials as Topic MeSH
- Parents MeSH
- Statistics as Topic MeSH
- Strabismus MeSH
- Vision, Binocular MeSH
- Treatment Outcome MeSH
- Visual Acuity MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Infant, Newborn MeSH
- MeSH
- Aphakia MeSH
- Demography MeSH
- Diagnostic Techniques, Ophthalmological MeSH
- Child MeSH
- Glaucoma * diagnosis surgery MeSH
- Data Interpretation, Statistical MeSH
- Infant MeSH
- Humans MeSH
- Mitomycin * therapeutic use MeSH
- Adolescent MeSH
- Intraocular Pressure MeSH
- Postoperative Complications MeSH
- Child, Preschool MeSH
- Retrospective Studies MeSH
- Risk Factors MeSH
- Statistics as Topic MeSH
- Trabeculectomy * MeSH
- Visual Acuity MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Adolescent MeSH
- Male MeSH
- Child, Preschool MeSH
- Female MeSH
- MeSH
- Aphakia, Postcataract MeSH
- Child MeSH
- Glaucoma Drainage Implants MeSH
- Drug Therapy contraindications utilization MeSH
- Glaucoma, Open-Angle * etiology complications therapy MeSH
- Glaucoma MeSH
- Lens Implantation, Intraocular MeSH
- Incidence MeSH
- Infant MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
- Risk Factors MeSH
- Cornea MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
PURPOSE: To determine the central corneal thickness (CCT) in microphthalmic aphakic or pseudophakic eyes as well as in microphthalmic eyes without any history of eye surgery. METHODS: Thirty-two patients with a mean age of 6.41±5.24 years after congenital cataract surgery with absolute microcornea, i.e., horizontal corneal diameter (HCD)<10 mm, or relative microcornea, i.e., HCD 10-11 mm but in the affected eye at least 0.5 mm smaller compared to the fellow eye, formed group A. Thirteen patients of mean age 0.94±1.22 years with absolute or relative microcornea plus another developmental anomaly of an eye without any history of eye surgery formed group B. The patients with corneal edema or scars were excluded. The control group consisted of 124 healthy school-aged children. Horizontal corneal diameter was measured with caliper and CCT with an ultrasound pachymeter. In infants, these measurements were performed under general anesthesia. RESULTS: In 48 eyes in group A and in 16 eyes in group B, the mean CCT was 635.13±65.35 µm and 642.31±93.07 µm, respectively, which was significantly greater (p<0.0001 and p=0.0018) in comparison with the mean CCT (553.58±33.12 µm) in the control group. Regression curve demonstrated the significant increase of CCT values along with the decrease of HCD in microphthalmic eyes. CONCLUSIONS: Small corneas in microphthalmic eyes either with or without congenital cataract surgery have significantly higher CCT. The results demonstrate significant negative correlation between horizontal corneal diameter and CCT.
- MeSH
- Aphakia, Postcataract pathology MeSH
- Diagnostic Techniques, Ophthalmological MeSH
- Child MeSH
- Cataract Extraction MeSH
- Cataract congenital MeSH
- Infant MeSH
- Humans MeSH
- Microphthalmos pathology MeSH
- Child, Preschool MeSH
- Pseudophakia pathology MeSH
- Cornea abnormalities pathology MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Male MeSH
- Child, Preschool MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- MeSH
- Aphakia, Postcataract MeSH
- Child MeSH
- Cataract Extraction MeSH
- Lens Implantation, Intraocular MeSH
- Cataract therapy congenital MeSH
- Infant MeSH
- Contact Lenses MeSH
- Humans MeSH
- Check Tag
- Child MeSH
- Infant MeSH
- Humans MeSH
- Publication type
- Meeting Abstract MeSH
- MeSH
- Aphakia, Postcataract MeSH
- Child MeSH
- Cataract Extraction MeSH
- Lens Implantation, Intraocular MeSH
- Cataract congenital MeSH
- Contact Lenses MeSH
- Humans MeSH
- Infant, Premature, Diseases MeSH
- Infant, Newborn MeSH
- Eye Diseases congenital MeSH
- Child, Preschool MeSH
- Prospective Studies MeSH
- Vision, Binocular MeSH
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities MeSH
- Visual Acuity MeSH
- Check Tag
- Child MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Child, Preschool MeSH
- Publication type
- Comparative Study MeSH
