99 s. : 5 tab.
- MeSH
- Aerosols therapeutic use MeSH
- Administration, Inhalation methods standards MeSH
- Respiratory Therapy microbiology instrumentation MeSH
- Aerosol Propellants standards MeSH
- Humans MeSH
- Nebulizers and Vaporizers MeSH
- Powders therapeutic use MeSH
- Particle Size MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
Nechtík lekársky obsahuje komplex látok, ktoré sa do extraktov a následne potom do dermálnych prípravkov dostávajú v množstve, ktoré závisí od ich polarity a polarity vyluhovadla. Prípravky s obsahom nechtíkových extraktov potom obsahujú prednostne buď v tukoch rozpustné karotenoidy, alebo hydrofúnejšie flavonoidy. V práci sa overovala možnosť prípravy dermálneho prípravku, ktorý by obsahoval celý komplex obsahových látok drogy. Pripravili sa hydro- a oleokrémy, v ktorých obidve fázy emulzného systému sú obohatené o príslušné obsahové látky nechtíka. Krémy sa hodnotili z aspektu ich tokových parametrov. Státím sa viskozita hydrokrémov mierne znižovala, oleokrémov zvyšovala. Modifikáciou zloženia a výberom emulgátora dá sa modifikovať štruktúra, typ krému, ako aj jeho viskozita z aspektu dosiahnutia optimálnej aplikácie a účinku.
Calendula officinalis L. contains a complex of substances which enter extracts and then dermal preparations in an amount dependent on their polarity and the polarity of the extraction agent. Preparations containing Calendula extracts then contain preferentially either fat-soluble carotenoids, or more hydrophilic flavonoids. The paper has verified possible preparation of a dermal preparation which would contain the whole complex of the drug constituents. Hydro- and oleocreams have been prepared, in which both phases of the emulsion system are enriched by the pertinent Calendula constituents. Creams were evaluated from the aspect of its flow parameters. Standing slightly decreased the viscosity of hydrocreams and increased that of oleocreams. A modification of the composition and a selection of the emulsifier can modify the structure, type of cream, as well as its viscosity from the aspect of achieving optimal application and effect.
- MeSH
- Antifungal Agents pharmacology therapeutic use MeSH
- Administration, Cutaneous MeSH
- Gels MeSH
- Drug Evaluation MeSH
- Immunodiffusion MeSH
- Dosage Forms MeSH
- Humans MeSH
- Viscosity MeSH
- Check Tag
- Humans MeSH
- Publication type
- Comparative Study MeSH
- MeSH
- Antifungal Agents pharmacology therapeutic use MeSH
- Administration, Cutaneous MeSH
- Gels MeSH
- Drug Evaluation MeSH
- Immunodiffusion MeSH
- Dosage Forms MeSH
- Humans MeSH
- Viscosity MeSH
- Check Tag
- Humans MeSH
- Publication type
- Comparative Study MeSH
