Q95167044 Dotaz Zobrazit nápovědu

Přesná shoda Sémantické

Cílem této prospektivní studie je pomocí analýzy videostroboskopických záznamů porovnat pacienty s benigními a maligními lézemi hlasivek zařazené do skupin A (7 pacientů) s dlaždicobuněčným karcinomem, B (10 pacientů) s dysplázií I.-III. stupně, C (11 pacientů) s edémy hlasivek, D (15 pacientů) s cystou na hlasivce, E (26 pacientů) s polypem hlasivky a do kontrolní skupiny F (11 pacientů). Celkem se studie zúčastnilo 80 pacientů, 31 mužů a 49 žen. Pro vyhodnocení záznamů byla vybrána maximální šíře štěrbiny v oblasti zadní komisury na amplituda slizniční vlny. Průměrná maximální šíře štěrbiny byla zvětšená nejméně u skupiny B a dále v pořadí skupina A, C, E a D. U kontrolní skupiny nabývala maximální šíře štěrbiny nejnižší průměrné hodnoty. Slizniční vlna byla nejméně postižena u skupiny pacientů s cystou na hlasivce. Největší postižení slizniční vlny bylo ve vzestupném pořadí u skupiny pacientů s edémem nebo polypem hlasivek.

The objective of this prospective study is to use videostroboscopic recordings for comparing probands with benign and malignant lesions of vocal cords with a control group of patients. According to null hypothesis there is no difference between videostroboscopic recordings of the groups A, B, C, D, E and F. A total of 80 patients were included in the study, 31 men and 49 women. The probands were accordingly divided into 5 groups: Group A included 7 patients with squamous cell carcinoma of vocal cord at the T1 or T2 stage, group B included 10 patients with dysplasia of I-III degree, group C encompassed 11 patients with vocal cord oedema, group D included 15 patients with a cyst on vocal fold and group E contained 26 patients with a benign polyp on one of the folds. The control group F embraced 11 patients with negative laryngological anamnesis and a normal voice. In order to evaluated videostroboscopic recordings and their quantification for statistical evaluation, two parameters were selected: maximum width of the opening (rima glottis) in the region of comissura posterior during phonation and amplitude of mucous wave during phonation. The width was evaluated as none, 1 mm, 2-3 mm, or more than 3 mm. The amplitude of mucous wave was evaluated as increased, normal, decreased or completely absent. It is possible to say that the mean maximum width of the opening in the area of comissura posterior was enlarged especially in group B (dysplasia) and further in the order of group A (carcinomas), group C (oedemas), groups E (polyps) and group D (cysts). In the control group F the maximum width of opening in the comissura posterior region reached the lowest mean value. The mucous wave was the least affected one in control group F without any disease of larynx and in group D of patients with vocal folds affected by cysts, where it was normal in 100%. The mucous wave was increasingly affected in the order of group E with polyps, in group A with oedemas, in group B with dysplasia and in group A of patients with carcinoma of vocal folds.