Struhárová, I*
Dotaz
Zobrazit nápovědu
- Klíčová slova
- stres, pracovní prostředí, dotazníkový průzkum, stresory, recenzovaný článek,
- MeSH
- porodní asistentky MeSH
- MeSH
- bylinné čaje MeSH
- fytoterapie * metody MeSH
- komplementární terapie metody MeSH
- léčivé rostliny MeSH
- lidé MeSH
- melasa MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- populární práce MeSH
Aim: The aim of this work was to map awareness and the satisfaction of pregnant women who received psychoprofylactic preparation for childbirth. At the same time, to identify the differences in knowledge, skills and attitudes of pregnant women in terms of age, reached levels of education and parity. Methodology and file: Filed respondents comprised 100 pregnant women hospitalized after the delivery at Gynecology-Obstetrics Clinics in Trencin in the period from January to April 2010. For collection of data own questionnaire was used. The observed characteristics (age, education, parity) were compared in women who underwent psychoprofylactic preparation for childbirth (n = 53) with those which did not undergo psychoprofylactic preparation for childbirth (n = 47). The results were evaluated by Chi-square test. Results: Psychoprofylactic preparation for childbirth was attended by 53 % of respondents from the total number of pregnant women, from which there were significantly more pregnant women who were highly educated (p = 0.001) as well as the women who had given birth for the first time (p = 0.033). Of them stated the use of information about the course of a child delivery 90.6 %, especially proper breathing during childbirth, relieving positions, massage and exercise on fitness balls. We did not record any difference in the method of the child delivery among women who attended prenatal courses and those who did not attend (p = 0.505). Conclusion: The results show the significance of the preparation for the childbirth. Among women who had given birth to the child for the first time, quality preparation for childbirth does not lead to significant reduction of the incidence of adverse obstetric complications. However, women positively evaluate the importance of information obtained during the course of prenatal preparation. It is necessary to raise awareness about the possibility of visiting the PPP and the cooperation between maternity hospitals and providers of prenatal courses. Based on the results obtained is feasible to say that the need for psychoprofylactic preparation for pregnant women is an inherent part of prenatal care.
- MeSH
- lidé MeSH
- odhad potřeb MeSH
- prenatální péče metody statistika a číselné údaje MeSH
- průzkumy a dotazníky MeSH
- spokojenost pacientů statistika a číselné údaje MeSH
- těhotné ženy psychologie MeSH
- vzdělávání pacientů jako téma metody statistika a číselné údaje MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
Merala sa rozpustnost kalciového antagonistu nimodipínu vo vode a vo vodných roztokoch β-cyklodextrínu (β-CD, až 0,014 mol/l) a rozpustnejšieho hydroxypropyl-β-cyklodextrínu (HP-β-CD, až 0,05 mol/l) s priememým stupňom substitúcie 0,8. Zvýšenie rozpustnosti bolo priamoúmerné koncentrácii cyklodextrínu, pričom v roztoku β-CD bola rozpustnost nimodipínu až 2,2 mg/100 ml, v roztoku HP-β-CD až 6 mg/100 ml, za daných podmienok po 14 dňoch rozpúšťania. Riedením vodou sa takto solubilizovaný nimodipín nezráža. Zo smerníc lineárnych fázových diagramov rozpustnosti sa vypočítali príslušné asociačné konštanty tvorby inklúznych komplexov (1:1) v roztoku nimodipínu s β-CD (401 mol-1 1) a s HP-p-CD (268 mol-1 1). Kinetika rozpúšťania substancie nimodipínu v roztoku HP-β-CD sledovaná od 3 min. až po 14 dní sa vyznačovala oscilováním medzi presýteným roztokom a rozpúšťacou rovnováhou, pre prípravu stálych roztokov v rozpúšťacej rovnováhe sa preto odporúča merať disolučnú krivku v dlhšom časovom intervale. Rozotieracou metódou sa pripravili veľmi lahko rozpustné tuhé zmesi nimodipínu s HP-β-CD a termickou analýzou sa dokázala tvorba tuhého komplexu 1:1.
The solubility of the calcium antagonist nimodipine was measured in water and in aqueous solutions of both β-cyclodextrin (β-CD, up to 0.014 mol/l) and the more soluble hydroxypropyl-β-cyclodextrin (HP-β-CD, up to 0.05 mol/l) with an average substitution degree of 0.8. The solubility enhancement of nimodipine was proportional to the cyclodextrin concentration, it was up to 2.2 mg/100 ml and 6 mg/100 ml in the respective solutions of β-CD and HP-β-CD, under the studied conditions, after 14 days of nimodipine dissolution. The solubilized nimodipine does not precipitate on diluting the Solutions with water. The association constant of the inclusion complexes (1:1) were evaluated from the slopes of the linear phase solubility diagrams of nimodipine in the respective solutions of β-CD (401 mol-1 1) and HP-β-CD (268 mol-1 1). The kinetics of dissolution of the solid nimodipine in the solution of HP-β-CD was followed from 3 min till 14 days and oscillations between the supersaturation and the equilibrium solution were observed. Long term measurements of the dissolution curve are thus recommended if stable solutions, in terms of the solubility equilibrium, are to be prepared. Easily soluble solid mixtures of nimodipine with HP-β-CD were prepared by the kneading method and the formation of the solid complex 1:1 was demonstrated by the differential thermal analysis.
