polyamide
Dotaz
Zobrazit nápovědu
- MeSH
- dimethylpolysiloxany chemie MeSH
- nylony chemie MeSH
- ortopedie * MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- MeSH
- celulosa farmakologie MeSH
- chronické selhání ledvin terapie MeSH
- dospělí MeSH
- kardiovaskulární nemoci diagnóza etiologie mortalita MeSH
- lidé MeSH
- nylony farmakologie MeSH
- peritoneální dialýza metody MeSH
- těhotenský plazmatický protein A metabolismus MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
The injured or otherwise damaged cornea is healed by limbal stem cells (LSC). If the limbus where LSC reside is also damaged or nonfunctional, the cornea cannot heal properly and this defect leads to impaired vision that can result in blindness. The only way to treat total LSC deficiency is by transplantation of limbal tissue or a transfer of LSC. Recently, mesenchymal stem cells (MSC) have been shown as another promising source of stem cells for corneal healing and regeneration. Here, we describe a protocol for the use of polyamide 6/12 nanofiber scaffolds for the growth of MSC and LSC, and for their transfer onto a mechanically damaged ocular surface in the experimental mouse model.
- MeSH
- buněčné kultury MeSH
- CD antigeny metabolismus MeSH
- dospělé kmenové buňky metabolismus transplantace MeSH
- kultivované buňky MeSH
- lidé MeSH
- limbus corneae cytologie MeSH
- mezenchymální kmenové buňky fyziologie MeSH
- myši inbrední BALB C MeSH
- myši MeSH
- nanovlákna chemie MeSH
- nylony chemie MeSH
- separace buněk MeSH
- tkáňové podpůrné struktury chemie MeSH
- transplantace mezenchymálních kmenových buněk * MeSH
- tvar buňky MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
Contributions to nephrology ; 96
1st ed. ix, 148 s.
- MeSH
- membrány umělé MeSH
- nefrologie MeSH
- polyaminy MeSH
- Publikační typ
- monografie MeSH
- Konspekt
- Patologie. Klinická medicína
- NLK Obory
- nefrologie
Contributions to nephrology ; 96
1st ed. IX, 148 s. : 64 obr., 14 tab., přeruš.lit., věc.rejstř. ; 24 cm
An open randomised prospectively controlled trial was performed to assess the healing efficacy, slippage rate and degree of discomfort on removal of calcium alginate and a silicone-coated polyamide net dressing on split skin graft donor sites. Sixteen patients were randomised to the calcium alginate group and 14 to the silicone-coated group. The donor sites were assessed at days 7, 10, 14 and up to day 21. The mean time to healing in the cal- cium alginate group was 8.75 ± 0.78 days (range 7 to 14 days) compared to 12 ± 0.62 days (range 7 to 16 days) for the silicone-coated group (p < 0.01). Although more silicone-coated dressings slipped (5 versus 1), the differ- ence was not statistically significant. Pain during the first dressing change was assessed using a visual analogue pain scale. Although no significant differences were found between the groups, it was necessary to change the dressing protocol in the silicone-coated arm of the trial after entering the first two patients. Overlaid absorbent gauze adhered to the donor site through the fenestrations in the dressing necessitating the placement of paraffin gauze between the experimental dressing and the overlying cotton gauze. There was one infection in the study, occuring in the alginate group. Based on these results we recommend calcium alginate as the dressing of choice for spilt skin graft donor sites.
