Chromatin dynamics of plant telomeres and ribosomal genes
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
25752316
DOI
10.1111/tpj.12822
Knihovny.cz E-resources
- Keywords
- Arabidopsis thaliana, Nicotiana tabacum, chromatin, epigenetics, rDNA, telomere,
- MeSH
- Chromatin chemistry metabolism MeSH
- DNA, Plant chemistry metabolism MeSH
- Epigenesis, Genetic MeSH
- Histones genetics metabolism MeSH
- Genomic Instability MeSH
- DNA Replication MeSH
- DNA, Ribosomal chemistry metabolism MeSH
- Plants genetics MeSH
- Telomere genetics metabolism MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Chromatin MeSH
- DNA, Plant MeSH
- Histones MeSH
- DNA, Ribosomal MeSH
Telomeres and genes encoding 45S ribosomal RNA (rDNA) are frequently located adjacent to each other on eukaryotic chromosomes. Although their primary roles are different, they show striking similarities with respect to their features and additional functions. Both genome domains have remarkably dynamic chromatin structures. Both are hypersensitive to dysfunctional histone chaperones, responding at the genomic and epigenomic levels. Both generate non-coding transcripts that, in addition to their epigenetic roles, may induce gross chromosomal rearrangements. Both give rise to chromosomal fragile sites, as their replication is intrinsically problematic. However, at the same time, both are essential for maintenance of genomic stability and integrity. Here we discuss the structural and functional inter-connectivity of telomeres and rDNA, with a focus on recent results obtained in plants.
References provided by Crossref.org
Identification of the Sequence and the Length of Telomere DNA
Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
G4 Structures in Control of Replication and Transcription of rRNA Genes
Tidying-up the plant nuclear space: domains, functions, and dynamics
An armadillo-domain protein participates in a telomerase interaction network
Variation of 45S rDNA intergenic spacers in Arabidopsis thaliana
Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant Cell
Telomere binding protein TRB1 is associated with promoters of translation machinery genes in vivo
