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Article

PubMed

This record comes from PubMed

Population genomics of Bronze Age Eurasia

Nature. 2015 Jun 11 ; 522 (7555) : 167-72.

ISSN 1476-4687 | 0028-0836
Source

Language English Country Great Britain, England Media print

Document type Historical Article, Journal Article, Research Support, Non-U.S. Gov't

Persistent link https://www.medvik.cz/link/pmid26062507

PubMed 26062507
DOI 10.1038/nature14507
PII: nature14507
Knihovny.cz E-resources

MeSH
Archaeology methods MeSH
Asian People genetics MeSH
White People genetics MeSH
History, Ancient MeSH
DNA genetics isolation & purification MeSH
Gene Frequency genetics MeSH
Genome, Human genetics MeSH
Genomics * MeSH
Language history MeSH
Polymorphism, Single Nucleotide genetics MeSH
Cultural Evolution history MeSH
Humans MeSH
Human Migration history MeSH
Lactose Intolerance genetics MeSH
Skin Pigmentation genetics MeSH
Genetics, Population MeSH
Fossils * MeSH
Check Tag
History, Ancient MeSH
Humans MeSH
Publication type
Journal Article MeSH
Historical Article MeSH
Research Support, Non-U.S. Gov't MeSH
Geographicals
Asia ethnology MeSH
Europe ethnology MeSH
Names of Substances
DNA MeSH

The Bronze Age of Eurasia (around 3000-1000 BC) was a period of major cultural changes. However, there is debate about whether these changes resulted from the circulation of ideas or from human migrations, potentially also facilitating the spread of languages and certain phenotypic traits. We investigated this by using new, improved methods to sequence low-coverage genomes from 101 ancient humans from across Eurasia. We show that the Bronze Age was a highly dynamic period involving large-scale population migrations and replacements, responsible for shaping major parts of present-day demographic structure in both Europe and Asia. Our findings are consistent with the hypothesized spread of Indo-European languages during the Early Bronze Age. We also demonstrate that light skin pigmentation in Europeans was already present at high frequency in the Bronze Age, but not lactose tolerance, indicating a more recent onset of positive selection on lactose tolerance than previously thought.

] Center for Biological Sequence Analysis Department of Systems Biology Technical University of Denmark 2800 Kgs Lyngby Denmark [2] Novo Nordisk Foundation Center for Protein Research University of Copenhagen 2200 Copenhagen Denmark

] Centre for GeoGenetics Natural History Museum University of Copenhagen Øster Voldgade 5 7 1350 Copenhagen K Denmark [2] Faculty of Archaeology Leiden University 2300 Leiden The Netherlands

] Department of Biological Anthropology Institute of Biology Eötvös Loránd University H 1117 Budapest Hungary [2] Department of Anthropology Hungarian Natural History Museum H 1083 Budapest Hungary

] Hungarian National Museum H 1083 Budapest Hungary [2] Department of Biological Anthropology University of Szeged H 6726 Szeged Hungary

] Institute of Archaeology and Museology Faculty of Arts Masaryk University CZ 602 00 Brno Czech Republic [2] Department of Vegetation Ecology Institute of Botany of the Czech Academy of Sciences CZ 602 00 Brno Czech Republic

Archaeological Institute University of Zurich CH 8006 Zurich Switzerland

Archaeological Superintendence of Lombardy 20123 Milano Italy

Biocentre of the Ludwig Maximilian University München 82152 Munich Germany

Center for Biological Sequence Analysis Department of Systems Biology Technical University of Denmark 2800 Kgs Lyngby Denmark

Center for Theoretical Evolutionary Genetics University of California Berkeley California 94720 3140 USA

Centre for GeoGenetics Natural History Museum University of Copenhagen Øster Voldgade 5 7 1350 Copenhagen K Denmark

Department of Anatomy Wrocław Medical University 50 368 Wrocław Poland