Originally a remembrance of an elderly physiologist, this paper illustrates the need for a standardized specification of certain experimental or survey conditions beyond those usually necessarily disclosed in conventional publications, namely calendar-dates, clock-times and geographic locations, to allow reference to helio-ionosphero-geomagnetics along with natural and artificial lighting and temperature. When possible, body times given by a marker rhythm also should be specified. A personalized chronobiologic cybercare can eventually include focus on infradians, beyond circadians. Benefits from longitudinal monitoring are: 1. Chronobiologically-interpreted blood pressure (BP) and heart rate (HR) monitoring enables the diagnosis and treatment of Vascular Variability Anomalies (VVAs) or, if lasting in several 7-day records, Disorders (VVDs), not yet screened for in practice, that increase cardiovascular disease risk independently of an elevated BP. 2. The optimal treatment time for the individual patient can be determined and potential harm avoided, since the same dose of the same medication for the same patient can help or harm depending only on when it is administered. 3. Benefit may be derived in cancer treatment timed according to marker rhythmometry. 4. The change from a spotcheck-based health care to one of internet-aided systematic self-surveillance by the automatic collection and analysis of time series stems from evidence that nonphotic and photic environmental influences affect biota, associations that may depend on geographic and temporal location. 5. Imaging in time includes formatting for time, globally and locally, for the mapping of a transdisciplinary spectrum of cycles involving "good" and "bad" strain in human physiology, versus sudden cardiac death, suicide and terrorism, all latter requiring rational countermeasures.
- MeSH
- biologické hodiny MeSH
- chronobiologie (obor) metody trendy MeSH
- chronoterapie metody normy využití MeSH
- cirkadiánní rytmus MeSH
- financování organizované MeSH
- kardiovaskulární nemoci prevence a kontrola MeSH
- léková chronoterapie MeSH
- lidé MeSH
- měření krevního tlaku MeSH
- nádory terapie MeSH
- náhlá srdeční smrt prevence a kontrola MeSH
- periodicita MeSH
- prevence sebevražd MeSH
- referenční standardy MeSH
- sebevražda MeSH
- srdeční frekvence MeSH
- statistika jako téma MeSH
- terorismus prevence a kontrola MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- chronobiologické jevy imunologie účinky léků MeSH
- chronoterapie metody trendy využití MeSH
- cirkadiánní rytmus genetika imunologie účinky léků MeSH
- experimenty na zvířatech MeSH
- farmaceutická technologie metody MeSH
- farmakologie metody MeSH
- farmakoterapie metody využití MeSH
- léková chronoterapie MeSH
- lidé MeSH
- nádorové biomarkery MeSH
- nádorové procesy MeSH
- sliny enzymologie účinky léků MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- recenze MeSH
- Klíčová slova
- cirkadiánní poruchy endokrinního systému,
- MeSH
- cirkadiánní rytmus * fyziologie genetika imunologie MeSH
- dehydroepiandrosteron fyziologie metabolismus MeSH
- depresivní poruchy enzymologie etiologie komplikace MeSH
- endokrinní systém * abnormality enzymologie patofyziologie MeSH
- estradiol izolace a purifikace metabolismus MeSH
- financování organizované MeSH
- hormony izolace a purifikace metabolismus MeSH
- hydrokortison fyziologie metabolismus MeSH
- krevní oběh - doba MeSH
- krevní tlak fyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- melatonin fyziologie izolace a purifikace metabolismus MeSH
- selen metabolismus MeSH
- statistika jako téma MeSH
- testosteron fyziologie izolace a purifikace metabolismus MeSH
- únava enzymologie etiologie komplikace MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
- Klíčová slova
- délka lunárního dne je 24.84 h, lidské biologické rytmy během a po izolaci v podzemí,
- MeSH
- chronobiologické jevy fyziologie genetika imunologie MeSH
- cirkadiánní rytmus * fyziologie MeSH
- endokrinní systém fyziologie MeSH
- experimenty na lidech MeSH
- experimenty na zvířatech MeSH
- financování organizované MeSH
- kardiovaskulární systém patofyziologie MeSH
- lidé MeSH
- Měsíc MeSH
- metaanalýza jako téma MeSH
- planetární evoluce * MeSH
- příliv a odliv * dějiny klasifikace MeSH
- sociální izolace MeSH
- spánková medicína metody MeSH
- statistika jako téma MeSH
- tělesná teplota fyziologie MeSH
- únava etiologie patofyziologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
In an 89-year-old man (FH), who monitored his blood pressure (BP) and heart rate (HR) aroundthe- clock at half-hour intervals for decades (with interruptions) and continued to do so before, during and after cataract surgery, we seek any alterations in the time structure of BP and/or HR in relation to this intervention (even though FH recognized no anxiety himself). First, we look at BP and HR within the individualized range of the subject at the given time by a sequential test, and second by reference to broader standards derived from clinically healthy peers of the same gender and corresponding age. The sequential test applied to detect any abnormalities used an individualized reference standard and found changes hidden in the normal range of peers, while data remained within that range. In the week following successful mid-week surgery, the circadian amplitude of diastolic BP increased above peer limits, a reason for caution in the interpretation of the results during the week of intervention as possibly related to subconscious anxiety about the surgery. If they were so related at all, these abnormalities were exceeded by the pleasure (in retrospect “tension”) associated with preparations of materials for publication at a conference, including this report. Apart from testing for physical or emotional loads (stress), we advocate, for any and all estimations of health more generally, a chronobiologically interpreted ambulatory automatic 7-day/24-hour BP and HR monitoring (C-ABPM) as soon as an appointment for a preoperative or any other health check is made, including cataract surgery.
The aim of the study was to assess the time structure (chronome) of sudden cardiac death (SCD) in Austria. The daily incidence of SCD (ICD-10 I46.1) in Austria was obtained for the 4-year span from Jan 2002 to Dec 2005. Data were available separately for men and women. This data series was analyzed by linear-nonlinear rhythmometry. The major feature is the detection of a cis-half-year that is validated nonlinearly, the estimated period of the cis-half-year is 0.408 year (95% CI: 0.389, 0.426). It is concluded that the chronobiological analysis of sudden cardiac death in Austria showed the variability of total incidence with the period of a cis-half-year.
- MeSH
- astronomické jevy MeSH
- biofyzikální jevy MeSH
- chronobiologické jevy genetika MeSH
- chronobiologie (obor) MeSH
- dějiny lékařství MeSH
- financování organizované MeSH
- genetika dějiny trendy MeSH
- lidé MeSH
- mezioborová komunikace MeSH
- periodicita MeSH
- statistika jako téma dějiny metody MeSH
- věda dějiny metody trendy MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- Research Support, U.S. Gov't, P.H.S. MeSH
- Geografické názvy
- Česká republika MeSH
- Spojené státy americké MeSH
The aim of the study was to assess the time structure (chronome) of sudden cardiac death (SCD) in Austria. The daily incidence of SCD (ICD-10 I46.1) in Austria was obtained for the 4-year span from Jan 2002 to Dec 2005. Data were available separately for men and women. This data series was analyzed by linear-nonlinear rhythmometry. The major feature is the detection of a cis-half-year that is validated nonlinearly, the estimated period of the cis-half-year is 0.408 year (95% CI: 0.389, 0.426). It is concluded that the chronobiological analysis of sudden cardiac death in Austria showed the variability of total incidence with the period of a cis-half-year.
- MeSH
- chronobiologické jevy genetika MeSH
- financování organizované MeSH
- lidé MeSH
- náhlá srdeční smrt epidemiologie etiologie MeSH
- periodicita MeSH
- statistika jako téma metody MeSH
- výzkumný projekt MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- Research Support, U.S. Gov't, P.H.S. MeSH
- Geografické názvy
- Česká republika MeSH
- Rakousko MeSH
- MeSH
- biodiverzita MeSH
- časové faktory MeSH
- chronobiologické jevy genetika imunologie MeSH
- finanční podpora výzkumu jako téma MeSH
- lidé MeSH
- molekulární biologie trendy MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- srovnávací studie MeSH
- MeSH
- ambulantní monitorování krevního tlaku MeSH
- chronobiologické jevy genetika účinky záření MeSH
- finanční podpora výzkumu jako téma MeSH
- lidé MeSH
- matematické výpočty počítačové MeSH
- náhlá srdeční smrt epidemiologie etiologie prevence a kontrola MeSH
- periodicita MeSH
- prospektivní studie MeSH
- sluneční aktivita MeSH
- srdeční frekvence fyziologie účinky léků MeSH
- Check Tag
- lidé MeSH
