BACKGROUND: The metabolic syndrome (MS) is a clustering of cardiovascular risk. The high prevalence of metabolic syndrome among populations of lower socioeconomic status is a cause of concern and calls for an effective public health response. OBJECTIVES: The aim of this study was to determine the prevalence of metabolic syndrome in the Roma population compared with the non-Roma population in the eastern part of Slovakia and to determine the parameter which has the strongest association with metabolic syndrome. RESULTS: 123 Roma and 79 non-Roma patients with metabolic syndrome were evaluated. In the subgroup of Roma men, we found that waist circumference conferred the highest chance of MS (more than 12-times), followed by triglycerides (TG) (3.670-times). In the subgroup of non-Roma men, we found that waist circumference conferred the highest chance of MS (more than 16-times), followed by high-density lipoprotein (HDL) (4.348-times increased risk per one unit decrease in HDL). In the subgroup of Roma women as well as non-Roma women, we found that serum TG conferred the highest chance of MS, followed by waist circumference for Roma women. Comparing non-classical risk factors for MS we found that only age (with OR 1.977) and high-sensitivity C-reactive protein (hsCRP) (OR 1.887) were significant and independent predictors of MS in Roma men. Among Roma women apolipoprotein B100 was also found to be an independent predictor of MS, besides age and hsCRP. CONCLUSION: Our study confirmed that the prevalence of metabolic syndrome is strongly associated with hypertriglyceridemic waist, besides other risk factors, a marker of the atherogenic metabolic triad among younger Roma population, which may be the reason for the increased cardiovascular (CV) morbidity and mortality in elderly Roma compared with non-Roma. In light of these results, better prevention of CV events for Roma minority settlements in Slovakia should be provided.
- MeSH
- apolipoprotein B-100 krev MeSH
- biologické markery krev MeSH
- C-reaktivní protein MeSH
- charakteristiky bydlení statistika a číselné údaje MeSH
- dospělí MeSH
- index tělesné hmotnosti MeSH
- lidé středního věku MeSH
- lidé MeSH
- lipidy krev MeSH
- lipoproteiny HDL krev MeSH
- metabolický syndrom krev etnologie MeSH
- mladiství MeSH
- mladý dospělý MeSH
- obezita krev etnologie MeSH
- obvod pasu etnologie fyziologie MeSH
- odds ratio MeSH
- prevalence MeSH
- rizikové faktory MeSH
- Romové etnologie statistika a číselné údaje MeSH
- rozložení podle pohlaví MeSH
- triglyceridy krev MeSH
- věkové rozložení MeSH
- venkovské obyvatelstvo statistika a číselné údaje MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Slovenská republika MeSH
BACKGROUND: Obesity-induced metabolic syndrome is a multiple risk factor for cardiovascular (CV) risk factors and type 2 diabetes, and ethnic minorities seem to have unfavourable medical risk factors in general more frequently than majority populations. OBJECTIVE: The aim of this study was to evaluate the prevalence of cardiovascular risk factors in relation to metabolic syndrome in the Roma population compared with the non-Roma population residing in the eastern part of Slovakia. RESULTS: 123 Roma and 79 non-Roma patients with metabolic syndrome were evaluated. Men between 40-55 years of age had 4.76-times higher odds and women 5.26-times higher odds for metabolic sydrome compared with the younger population. We found statistically significant higher waist circumference in the Roma subpopulation and higher body mass index as well, although in selected population with metabolic syndrome. HDL cholesterol was significantly lower in both Roma men and women, and LDL cholesterol was not significant in men and women with metabolic syndrome. Triglycerides levels were significantly higher in non-Roma women only. High-sensitivity C-reactive protein (hsCRP) values were not in correlation with age but were associated with the increasing number of fulfilled criteria for metabolic syndrome in both subgroups (Roma, non-Roma), independently of gender. CONCLUSION: Our study confirmed higher prevalence of obesity, metabolic syndrome and other CV risk factors associated with metabolic syndrome among younger Roma population, which may be associated with increased cardiovascular disease (CVD) morbidity and mortality among elderly Roma compared with non-Roma.
- MeSH
- charakteristiky bydlení statistika a číselné údaje MeSH
- dospělí MeSH
- dyslipidemie etnologie MeSH
- index tělesné hmotnosti MeSH
- kardiovaskulární nemoci etnologie MeSH
- komorbidita MeSH
- lidé středního věku MeSH
- lidé MeSH
- metabolický syndrom etnologie MeSH
- mladiství MeSH
- mladý dospělý MeSH
- prevalence MeSH
- rizikové faktory MeSH
- Romové etnologie statistika a číselné údaje MeSH
- rozložení podle pohlaví MeSH
- věkové rozložení MeSH
- venkovské obyvatelstvo statistika a číselné údaje MeSH
- zánět etnologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Geografické názvy
- Slovenská republika MeSH
- MeSH
- echokardiografie využití MeSH
- kardiovaskulární nemoci diagnóza prevence a kontrola MeSH
- lehká atletika MeSH
- lidé MeSH
- mladiství MeSH
- náhlá srdeční smrt prevence a kontrola MeSH
- plošný screening etika trendy zákonodárství a právo MeSH
- prediktivní hodnota testů MeSH
- programy Healthy People MeSH
- riziko MeSH
- senzitivita a specificita MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
Práca sa zameriava na akútne metabolické komplikácie diabetes mellitus u seniorov, najmä na hyperosmolárny hyperglykemický syndróm (HHS). V priebehu roka 2008 bolo na Internú kliniku I. vo FNsP Prešov prijatých 14 pacientov pre HHS (priemerný vek 73,7 roka, SD ? 8,1 roka). Ako závažná komorbidita u týchto pacientov bola v siedmi prípadoch zistená jednostranná rozvinutá bronchopneumonia, v šiesti prípadoch urosepsa, jedna príčina vzniku HHS nebola známa. Štyria pacienti napriek intenzívnej liečbe zomreli ? pre srdcové zlyhanie dvaja pacienti, jeden pre embolizáciu do pľúc a jeden pacient pre malígnu poruchu rytmu. V odbornej literatúre je úmrtnosť na HHS v závislosti od komplikácií popisovaná od 10 % do 50 %. V geriatrickom veku je problematika HHS stále aktuálna, pretože štatisticky rastie pravdepodobnosť poruchy glukózovej tolerancie, prejavy diabetes mellitus môžu byť menej výrazné a okolie ich nevníma náležitým spôsobom. Seniori sa dostávajú do nemocnice zvyčajne pozde a liečba je potom finančne i časovo veľmi náročná.
In observation we shoot for the appearence of the metabolic complications of diabetes mellitus in senior? hyperglycemy hyperosmolary syndrom (HHS). During 2008 was in the Internal clinis and Clinic of geriatrics FNsP Prešov 14 patients with HHS hospitalized (average age 73.7 years, SD ? 8.1 years). As a major co-morbidity in these patients was in seven cases uniletarale bronchopneumony detected, in six cases was urosepsis detected, one cause of HHS was unknown, four patients died despite intensive treatment ? two patient died of heart failure, one patient died of tromboembolic disease and one patient died of maligny dysrytmy. In special literature is the mortality of HHS 10? 50%, depending of the complications. The problem of HHS is in the seniors always actual because in this age is statistic advanced appereance of the PGT and the showings of diabetes mellitus are lessmarkedly. The senior comes to the hospital usually later and than the treatment is challenge for the time an for the many.
- Publikační typ
- abstrakt z konference MeSH