Due to the limited availability of COVID-19 vaccines, occupational groups with priority access were identified prior to vaccination. The study aimed to analyze motives for vaccination in these occupational groups.METHODS: Members of occupational groups, who were vaccinated at the vaccination center of University Hospital Olomouc before 30 April 2021, were asked to fill in an online questionnaire. RESULTS: A total of 3224 completed questionnaires were obtained from 1332 healthcare workers, 1257 school employees, 363 social service workers, 210 security force members, and 62 critical infrastructure workers. The most frequent motive for vaccination was the effort to protect family members (76.2%), the effort to prevent the spread of COVID-19 in one's profession (72.3%), followed by concerns about COVID-19 itself (49.1%) and exemptions from anti-epidemic measures (36.8%). Only for social services, the motive focused on one's profession was mentioned more often (75.2%) than the motive focused on the family (71.1%). At the level of detailed profession-oriented motives, a collegial effort of security force members to protect co-workers and not to endanger the workplace was dominant. CONCLUSIONS: The effort to prevent the spread of COVID-19 in the professional environment is a strong motive for vaccination, and strongest among social service workers.
OBJECTIVES: The study focused on the relationship between routine clinical characteristics and anti-SARS-CoV-2 specific antibodies in a pilot sample of healthcare workers (HCWs) having suffered COVID-19. The aim was to investigate the existence of readily available predictors of antibodies against COVID-19. METHODS: As part of the recognition of COVID-19 as an occupational disease in 152 HCWs with the mean age of 43.2 years, personal, anthropometric and anamnestic data related to the disease as well as anti-spike immunoglobulin (Ig) levels were obtained. Through descriptive statistics, correlation and regression analyses, relationships of all variables and Ig levels, especially seropositivity of IgG, were investigated. RESULTS: The mean interval between the symptom onset and the determination of antibodies was 58 days. IgG seropositivity and IgM seropositivity were noted in 82 % and 49 % of HCWs, respectively. Symptom duration was the only statistically significant predictor of IgG seropositivity. With each day of symptom duration, the probability of IgG seropositivity increased from 1.078 to 1.092 times (p < 0.05). If symptoms lasted longer than 17 days, a majority (almost 80 %) of the subjects demonstrated seropositivity in the following months. CONCLUSION: The presence of IgG immunity may be assumed from symptom duration. Such easy recognizing of seropositive patients may be a useful tool, e.g. in vaccination strategies (Tab. 3, Fig. 1, Ref. 28).
- Klíčová slova
- séropozitivita, trvání nemoci,
- MeSH
- COVID-19 * imunologie MeSH
- dospělí MeSH
- imunoglobulin G * imunologie krev MeSH
- Kaplanův-Meierův odhad MeSH
- lidé středního věku MeSH
- lidé MeSH
- logistické modely MeSH
- nemoci z povolání imunologie MeSH
- průřezové studie MeSH
- regresní analýza MeSH
- statistika jako téma MeSH
- zdravotnický personál statistika a číselné údaje MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Česká republika MeSH
High vaccination coverage among healthcare workers (HCWs) is crucial for managing the COVID-19 pandemic. The aim was to determine the demand for vaccination among all employees (n = 4553) of a tertiary care hospital after several weeks of the vaccine's availability, and to analyze motives for acceptance and reasons for hesitancy through an anonymous online questionnaire. Upon the completion of data collection, the hospital's vaccination coverage was at 69.8%. A total of 3550 completed questionnaires were obtained (2657 from vaccinated, 893 from unvaccinated employees). Significant predictors of vaccine acceptance were: age (odds ratio (OR) 1.01, 95% confidence interval (CI) 1.01-1.02), sex (OR (females) 0.58, 95% CI 0.45-0.75), job type (OR (non-physician HCWs) 0.54, 95% CI 0.41-0.72; OR (non-HCWs) 0.51, 95% CI 0.37-0.71), fear of COVID-19 (OR 1.4, 95% CI 1.34-1.46), history of COVID-19 (OR 0.41, 95% CI 0.34-0.49) and of influenza vaccination (OR 2.74, 95% CI 2.12-3.57). The most frequent motive for acceptance was the effort to protect family members (84%), while concerns about vaccine safety and side effects (49.4%), followed by distrust in the vaccine's efficacy (41.1%) were the top reasons for hesitancy. To increase vaccination coverage among HCWs, it is necessary to raise awareness of vaccine safety and efficacy.
- Publikační typ
- časopisecké články MeSH
Protection of healthcare workers (HCWs) against influenza is essential for patient health and a functional health system. The study aimed to analyze the demand for seasonal influenza vaccination (SIV) among various groups of HCWs in a tertiary care hospital before and during the COVID-19 pandemic and to identify their motives for this season's SIV. Before this influenza season (2020/21), the hospital management offered free SIV to all HCWs and promoted it on the internal network. Out of 4,167 HCWs, 630 HCWs expressed interest in SIV and were vaccinated in the hospital. They filled in a total of 603 self-administered pen-and-paper questionnaires. The mean age of the respondents (374 females and 229 males) was 45 ± 12 years. Physicians accounted for 48% of the vaccinated persons but for only 24% (p < .001) of all HCWs to whom SIV was offered. Only 16% of respondents vaccinated this year also received SIV before the last season (2019/20), with the proportion of physicians (19%) being statistically significantly higher than that of non-physicians (13%, p = .045) and the proportion of chronically ill HCWs (22%) being higher than that of healthy individuals (13%, p = .004). Most frequently, respondents' motivation to get vaccinated this year was self-protection (61%), that is concerns about contracting influenza together with COVID-19 or alone, followed by family protection (58%) and patient protection (53%). In conclusion, COVID-19 contributed to an increased demand for SIV among HCWs and the threat of contracting it together with influenza was the most frequent motive.
- MeSH
- chřipka lidská * prevence a kontrola MeSH
- COVID-19 * MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- motivace MeSH
- pandemie MeSH
- postoj zdravotnického personálu MeSH
- průřezové studie MeSH
- průzkumy a dotazníky MeSH
- SARS-CoV-2 MeSH
- vakcinace MeSH
- vakcíny proti chřipce * MeSH
- zdravotnický personál MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
OBJECTIVES: Asbestos-related diseases are still a current problem worldwide. What is their occurrence in the Czech Republic? The answer is the subject of this study, which aims to provide a general and regional overview of the situation over the last 20 years with a more detailed focus on mesothelioma, the development of which is highly associated with asbestos exposure and the issue of their recognition as an occupational disease. METHODS: In its retrospective reviews, the study is based on analyses of data from the Institute of Health Information and Statistics of the Czech Republic and data from the Czech National Cancer Registry, which also interconnects. RESULTS: In the last 20 years, 512 new cases of occupational diseases from asbestos have been reported, namely 228 cases of pleural thickening, 133 mesotheliomas, 92 asbestoses, and 59 cases of lung cancer. In the last 5 years, mesotheliomas (n = 39) predominated among the reported diseases with a 45% proportion in the total number of 86 cases. The trend in their incidence, as the only one among asbestos-related diseases, is not declining. There was a significant difference in the overall incidence of mesothelioma in a general population and the incidence of occupational mesotheliomas. At the national level, occupational aetiology was acknowledged in only 11.3% of cases of mesothelioma on average. The highest proportion of occupational mesotheliomas and the highest incidence of all asbestos-related diseases were found in regions where the largest asbestos processing plants were located. CONCLUSION: The authors emphasize the importance of work history for the diagnostic process of asbestos-related diseases and also the need to perform follow-up examinations for their early detection.
- MeSH
- azbest * toxicita MeSH
- lidé MeSH
- mezoteliom * chemicky indukované epidemiologie MeSH
- nemoci z povolání * epidemiologie MeSH
- retrospektivní studie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- přehledy MeSH
- Geografické názvy
- Česká republika MeSH
OBJECTIVES: Malignant mesothelioma (MM) is the most serious asbestos-related disease. Its increasing incidence is alarming, suggesting the need for as early diagnosis as possible. This 4.5-year prospective longitudinal study aimed at assessing the benefit of measuring serum mesothelin as a marker for diagnosing malignant mesothelioma in individuals with previous occupational exposure to asbestos, as a part of their clinical follow-up care. MATERIAL AND METHODS: The study comprised 309 participants (235 males, 74 females) with a mean age of 58.9 years (standard deviation (SD) = 9.8) and a mean duration of exposure to asbestos dust of 13.4 years (SD = 9.3). From 2009 to June 2013, all subjects were followed at a department of occupational medicine in Olomouc. Apart from the standard parts of medical examination (history, physical examination, simple chest radiographs and spirometry), the patients' serum mesothelin levels were determined by the Mesomark immunoenzymatic diagnostic assay. Statistical analysis of the validity of serum mesothelin level measurement was carried out with respect to the diagnosis of MM. RESULTS: Among the participants, 16 (5.2%) individuals (14 males and 2 females) were diagnosed with malignant mesothelioma. Based on the detected mesothelin levels, their validity for prediction of malignant mesothelioma was calculated as follows: sensitivity - 0.75, specificity - 0.962, positive predictive value - 0.706, negative predictive value - 0.969, positive and negative likelihood ratios - 19.95 and 0.26, respectively, and diagnostic odds ratio - 76.8, at a 95% confidence interval. CONCLUSIONS: The high specificity was identified indicating the low false positivity as well. In the case of detecting elevated soluble mesothelin-related peptides (SMRP) levels in formerly asbestos-exposed individuals, the possibility of the presence of MM should be included into the clinical consideration. The high negative predictive value denotes a lower probability of the presence of MM in patients with normal SMRP levels but due to the limiting lower sensitivity this possibility cannot be entirely excluded.
- MeSH
- azbest toxicita MeSH
- GPI-vázané proteiny krev MeSH
- lidé středního věku MeSH
- lidé MeSH
- longitudinální studie MeSH
- mezoteliom krev diagnóza etiologie MeSH
- nádorové biomarkery krev MeSH
- pracovní expozice škodlivé účinky MeSH
- pracovní lékařství metody MeSH
- prediktivní hodnota testů MeSH
- prospektivní studie MeSH
- senioři MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- validační studie MeSH
Úvod a cíl: Syndrom karpálního tunelu je nejčastější periferní neuropatií horní končetiny. Cílem naší práce bylo ověření účinnosti autokinezioterapie s prvky neurodynamické mobilizace středového nervu, jako jedné z možností léčby syndromu karpálního tunelu (SKT). A dále ověřit, zda edukaci pacientů a klientů ohledně cvičení mohou provádět zaškolené všeobecné sestry. Metodika: Soubor tvořilo 27 probandů (54 případů SKT), kteří byli zaškoleni všeobecnou sestrou o způsobu provádění autokinezioterapie třemi specifickými cviky a tyto osoby byly vyzvány, aby samostatně cvičily aspoň jednou denně po dobu 3 měsíců. Sestra je v průběhu studie nejméně 2krát telefonicky kontaktovala a povzbuzovala je. Kontrolní skupinu tvořilo 12 probandů (24 případů SKT), kteří necvičili, ani nebyli jinak léčeni. Před započetím studie a po třech měsících trvání byla u všech pacientů zjišťována míra subjektivních obtíží zvlášť pro každou ruku pomocí dotazníku. Otázky v dotaznících byly zaměřeny na subjektivní obtíže spojené s projevy SKT a jemnou motoriku ruky. Na závěr bylo provedeno srovnání výskytu a míry potíží před cvičením a po něm a srovnání efektu cvičení ve sledované a kontrolní skupině. Dále byl zkoumán efekt cvičení u incipientních a pokročilých forem SKT. Výsledky: K subjektivnímu zlepšení potíží došlo signifikantně častěji u cvičících osob. Subjektivní zlepšení alespoň v jednom ze všech sledovaných parametrů bylo zaznamenáno u 40 případů syndromu karpálního tunelu u cvičících (tj. u 76,9 %), což bylo zlepšení signifikantně častější než u osob necvičících (p < 0,0001), kde zlepšení po třech měsících bylo uváděno pouze u 5 postižených končetin (20,8 %). Při porovnání efektu cvičení podle míry subjektivních obtíží včetně parametrů týkajících se jemné motoriky ruky nebyly statisticky signifikantní rozdíly mezi incipientními a pokročilými formami syndromu karpálního tunelu. Závěr: Autokinezioterapie je jednou z možností prevence a terapie syndromu karpálního tunelu. Pokud je cvičení prováděno, přináší pacientům úlevu. Studie svědčí o tom, že klienti po úvodním zaškolení všeobecnou sestrou dokáží cvičit samostatně.
Introduction and objective: The carpal tunnel syndrome is the most frequent neuropathy of upper extremities. Our work investigated whether auto-kinesiotherapy with elements of neurodynamic mobilization of nervus medianus is effective as one of the possibilities for treating the carpal tunnel syndrome (CTS). Moreover, we wanted to verify, whether education of the patients and clients regarding the exercise can be provided by general nurses. Methods: The cohort included 27 persons (54 cases of CTS), who were educated by a general nurse in the way how to perform auto-kinesiotherapy by three specific exercises and the persons were asked to exercise independently at least once daily for the period of three months. The nurse contacted and stimulated the subjects at least twice by phone during the study. The control group included 12 persons (24 cases of CTS) who did no exercise or were not treated in any way. The extent of subjective complaints regarding each arm was established by a questionnaire survey before and after three months of the study. The questions in the questionnaires were directed to subjective complaints associated with CTS manifestations and fine hand motor. In the conclusion the authors compared the occurrence and degree of the complaints between and after the exercise and compared the effects of exercise in the followed and control groups. Moreover, the effect of exercise in incipient and advanced forms of CTS was investigated. Results: Subjective improvement of the complaints occurred significantly more often in the exercising subjects, A subjective improvement of at least on the followed parameters was detected in 40 cases of the carpal tunnel syndrome in the exercising subjects (76.9%), which was significantly more frequent than in the persons who did not exercise (P = 0.0001), where improvement was reported only in five subjects (20.8%). In comparing the effect of exercise by the extent of subjective complaints including the parameters of fine hand motor, there was not any significant difference between incipient and advanced forms of carpal tunnel syndrome. Conclusion: Auto-kinesiotherapy is one of the possibilities for prevention and therapy of the carpal tunnel syndrome. Whenever the exercise is practiced, the patients encounter a relief. The study indicates that clients are capable to exercise independently after an entry education by a general nurse.
- Klíčová slova
- neurodynamická mobilizace,
- MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- nemoci z povolání MeSH
- péče o sebe * MeSH
- spokojenost pacientů statistika a číselné údaje MeSH
- syndrom karpálního tunelu * diagnóza rehabilitace MeSH
- terapie cvičením * metody MeSH
- výsledek terapie MeSH
- vzdělávání pacientů jako téma MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
