Michl, Martin*
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An article describes diagnostic difficulties in patient with giant renal cyst, erroneously diagnosed as ascites on ultrasonographic examination. Patient was initially suspected to have disseminated intraabdominal malignancy. Abdominal paracentesis of supposed ascites was performed. The diagnosis of giant renal cyst was finally made by CT and patient was treated surgically. The limitations of ultrasonographic examination are pointed out are and a brief review of similar cases is given.
- MeSH
- ascites ultrasonografie MeSH
- břicho ultrasonografie MeSH
- cystická onemocnění ledvin ultrasonografie MeSH
- diferenciální diagnóza MeSH
- lidé MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
Fluorescence anisotropy measurements were performed on a set of multichromophoric compounds, which contain a different number of aminopyrenyl moieties linked to a triazine ring, in order to reveal the nature of both the electronic excited states and relaxation pathways of the compounds. Our experimental results complement quantum chemical calculations. We propose that the lowest excited state from which fluorescence proceeds is localized on a single individual aminopyrene moiety. In contrast, excitation to a higher excited state is likely followed by a migration of energy to another nearby aminopyrene chromophore before the internal conversion to the emitting state takes place. We suggest that this migration is responsible for the experimentally measured decrease of fluorescence anisotropy of the studied compounds.
Souhrn: U ortognátních pacientů není výjimkou, že je vyžadováno komplexnější ošetření pacienta v orofaciální oblasti, nejenom tedy úprava postavení čelistí, ale nejčastěji i úprava samotného chrupu (změna tvaru korunek, náhrada chybějících zubů atd.). Proto je nutné do léčebného plánu zapojit více specialistů, mimo ortodontisty a maxilofaciálního chirurga také např. parodontologa, implantologa, protetika, ORL lékaře, plastického chirurga atd. Úspěšnost výsledku komplexní léčby závisí na precizním plánování postupu léčby ještě před začátkem terapie a na úzké spolupráci mezi uvedenými odborníky. Cílem autorů není demonstrace nového postupu či přístupu, pouze chtějí poukázat na – z jejich pohledu – uspokojivou spolupráci mezi jednotlivými specialisty.
Summary: It is not an exception in orthognatic patients that complex treatment of the patient is required. We don´t need only to modify position of the jaws but sometimes even the dentition itself (by changing the shape of the crown, replacing the missing teeth etc.). Therefore, it is necessary to involve more specialists, not only the orthodontist and maxillofacial surgeon but also an implantologist, prosthodontist, ENT physician, plastic surgeon, etc. The success of the complex treatment depends on the precise planning of the treatment procedure before the therapy is started and furthermore on close cooperation among those experts. The key message of the article is not to show new method or access to the treatment of patients but to demonstrate successful cooperation amongst specialties.
New N-triazinyl derivatives were synthesized by reaction of cyanuric chloride with 1- and 9-aminoanthracenes and subsequent nucleophilic substitution of chlorine atoms on triazinyl ring with methoxy and/or phenylamino groups. The compounds were characterized by (1)H and (13)C NMR and mass spectra. The influence of the chemical structure and solvent polarity on the UV/Vis absorption and fluorescence spectra and fluorescence quantum yields were investigated. Semi-empirical computations revealed highly polar CT states in singlet excited state manifold connected with charge-transfer from the hydrocarbon moiety to the triazinyl ring. The relationships between the CT-to-emitting state energy gap, solvent polarity and fluorescence quantum yield were discussed.
BACKGROUND: For more than 20 years, infection with the human papillomavirus (HPV) has been of a matter of interest not only to gynecologists but also to maxillofacial surgeons and othorhinolaryngologists. HPV is generally known to be involved in cervical cancer. Recently, there are many clinical studies pointed out the potentially dangerous connection between HPV infection and head and neck carcinomas (HNC). HPV infection was identified as a possible etiological factor in 15-30% of HNC. METHODS: Aim of this article is to summarize the recent knowledge about the HPV infection with regards to etiology of head and neck cancer. RESULTS: It has been proven that HPV infection is related to development of head and neck cancer and that the sexual behavior has played an important role in the viral transmission. HNC of viral etiology have been observed mostly in younger people; their curability is difficult and prognosis serious. CONCLUSION: Beside the well known correlation between developing of new head and neck cancer and bad habits (smoking, alcohol abuse, poor oral hygiene etc.) we should take into consideration the sexual promiscuity and alternative sexual practices. Vaccination against cervical cancer, recommended to young women, should be extended to their male partners to prevent the virus transmission and decrease the HNC incidence.
- MeSH
- financování organizované MeSH
- infekce papilomavirem diagnóza komplikace MeSH
- lidé MeSH
- nádory hlavy a krku diagnóza patofyziologie virologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
OBJECTIVE: Oropharyngeal cancers are a biologically heterogenous group of tumors with diverse risk factors including tobacco, alcohol, HPV, inherited disorders, the acquired immunodeficiency of Karposi's Sarcoma and non Hodgkin's lymphoma. In the Czech Republic, oropharyngeal cancers represent around 2% of all cancers. The treatment of these tumors is long and complex. Reconstructive procedures in maxillofacial oncosurgery demand good interdisciplinary collaboration and great professional preparedness of the surgical and nursing team. Patient age and stage of disease, including the presence of metastases are of key importance. A prerequisite for the success of surgical treatment is removal of the tumor with a sufficient safety margin. Reconstructive procedures then follow. AIM: To highlight the importance of radical tumor resection and describe reconstruction of the defect in a group of our patients. METHODS AND RESULTS: From 2008 to 2013, 23 patients with oropharyngeal carcinoma underwent radical surgical removal of tumor, followed by reconstruction of postoperative defects using distant and free flaps. The histopathology showed predominantly squamous cell carcinomas and one of Merkel cell carcinoma. 16 patients had malignant disease detected in III-IV. In only 7 cases was treatment initiated in the first and second stages of the disease. In these patients, the tumors were removed with a safety margin of healthy tissue and in none, did the basic cancer recur . The postoperative course in terms of flap engraftment and overall condition of the patient was uneventful. All of these patients still enjoy a good life quality with a current mean survival in range 5 - 76 months. Radical surgical removal of a malignant tumor in the early stages of the disease is associated with fewer postoperative complications and longer survival. CONCLUSION: To avoid the risk of local and/or systemic postoperative complications, appropriate patient selection is important. Overall, the traditional, classic reconstructive procedures with the use of prostheses, in many cases is still the best option in our experience.
- MeSH
- chirurgické laloky MeSH
- lidé MeSH
- Merkelův nádor chirurgie MeSH
- nádory kůže chirurgie MeSH
- nádory orofaryngu chirurgie MeSH
- reoperace MeSH
- spinocelulární karcinom chirurgie MeSH
- stomatochirurgické výkony metody MeSH
- výsledek terapie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
